AutismKB 2.0

Annotation Detail for LRP11


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Basic Information Top
Gene Symbol:LRP11 ( FLJ14735,MANSC3,MGC39092,bA350J20.3 )
Gene Full Name: low density lipoprotein receptor-related protein 11
Band: 6q25.1
Quick LinksEntrez ID:84918; OMIM: NA; Uniprot ID:LRP11_HUMAN; ENSEMBL ID: ENSG00000120256; HGNC ID: 16936
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus22 / 56401239
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult60 / 193912130
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor4 / 34366116
chondrosarcoma7 / 8282384
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor6 / 26384522
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal74 / 336030722
ovarian tumor3 / 7668239
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone2 / 7165527
bone marrow2 / 4880140
brain14 / 110098912
cervix4 / 4817183
connective tissue9 / 14925560
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye3 / 21105414
heart2 / 8962622
intestine9 / 23447238
kidney10 / 21177747
larynx0 / 241450 
liver4 / 20774319
lung44 / 336974130
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary3 / 10205129
pancreas10 / 21481246
parathyroid8 / 20539389
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta7 / 28082524
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis2 / 3304426
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1842_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.82 ± 0.35
Basal Forebrain4.43 ± 0.44
Basal Part of Pons5.23 ± 0.22
Cerebellar Cortex4.45 ± 0.26
Cerebellar Nuclei4.59 ± 0.47
Claustrum4.71 ± 0.71
Epithalamus4.98 ± 0.45
Frontal Lobe4.83 ± 0.42
Globus Pallidus4.48 ± 0.47
Hypothalamus4.39 ± 0.6
Insula4.66 ± 0.4
Limbic Lobe4.83 ± 0.43
Mesencephalon4.65 ± 0.48
Myelencephalon4.73 ± 0.5
Occipital Lobe4.77 ± 0.36
Parietal Lobe4.75 ± 0.48
Pontine Tegmentum4.65 ± 0.42
Striatum4.67 ± 0.53
Subthalamus4.83 ± 0.49
Temporal Lobe4.81 ± 0.43
Thalamus4.56 ± 0.49
White Matter4.27 ± 0.99
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lrp11CBCerebellum50.86
100
Lrp11CTXCerebral cortex100
100
Lrp11HIPHippocampal region100
100
Lrp11HPFHippocampal formation100
100
Lrp11HYHypothalamus100
100
Lrp11LSXLateral septal complex100
100
Lrp11MBMidbrain100
100
Lrp11MYMedulla100
100
Lrp11OLFOlfactory bulb100
100
Lrp11PPons91.07
100
Lrp11PALPallidum100
100
Lrp11RHPRetrohippocampal region100
100
Lrp11sAMYStriatum-like amygdalar nuclei100
100
Lrp11STRStriatum100
100
Lrp11STRdStriatum dorsal region100
100
Lrp11STRvStriatum ventral region100
100
Lrp11THThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018