AutismKB 2.0

Annotation Detail for MASTL


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Basic Information Top
Gene Symbol:MASTL ( FLJ14813,RP11-85G18.2,THC2 )
Gene Full Name: microtubule associated serine/threonine kinase-like
Band: 10p12.1
Quick LinksEntrez ID:84930; OMIM: 608221; Uniprot ID:MASTL_HUMAN; ENSEMBL ID: ENSG00000120539; HGNC ID: 19042
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst6 / 6231996
fetus14 / 56401224
neonate2 / 3109764
infant4 / 23620169
juvenile2 / 5555635
adult73 / 193912137
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor3 / 3436687
chondrosarcoma4 / 8282348
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor22 / 26384583
glioma0 / 1068830 
head and neck tumor10 / 13630273
kidney tumor3 / 6895943
leukemia2 / 9584220
liver tumor4 / 9635941
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal97 / 336030728
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites4 / 4001599
bladder0 / 297570 
blood2 / 12347816
bone7 / 7165597
bone marrow1 / 4880120
brain23 / 110098920
cervix3 / 4817162
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue14 / 21572264
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine5 / 23447221
kidney8 / 21177737
larynx0 / 241450 
liver12 / 20774357
lung3 / 3369748
lymph0 / 442700 
lymph node4 / 9161043
mammary gland9 / 15327158
mouth8 / 67052119
muscle8 / 10771574
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta11 / 28082539
prostate1 / 1893455
salivary gland0 / 201550 
skin8 / 21057437
spleen2 / 5395237
stomach2 / 9661920
testis27 / 33044281
thymus5 / 8113161
thyroid2 / 4747342
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus7 / 23287830
vascular3 / 5178057
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P201988
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.22 ± 0.75
Basal Forebrain3.54 ± 0.69
Basal Part of Pons4.16 ± 0.49
Cerebellar Cortex3.88 ± 0.57
Cerebellar Nuclei4.72 ± 0.89
Claustrum4.25 ± 0.63
Epithalamus3.88 ± 0.35
Frontal Lobe4 ± 0.46
Globus Pallidus4.27 ± 0.41
Hypothalamus3.96 ± 0.57
Insula3.81 ± 0.49
Limbic Lobe3.93 ± 0.47
Mesencephalon3.98 ± 0.56
Myelencephalon3.96 ± 0.57
Occipital Lobe3.91 ± 0.63
Parietal Lobe4.05 ± 0.47
Pontine Tegmentum3.91 ± 0.51
Striatum3.69 ± 0.71
Subthalamus4.24 ± 0.2
Temporal Lobe3.97 ± 0.58
Thalamus3.81 ± 0.44
White Matter4.19 ± 0.51
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00424016 12 446 457 NFELVDSSPCKK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018