AutismKB 2.0

Annotation Detail for RAB2B


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Basic Information Top
Gene Symbol:RAB2B ( FLJ14824 )
Gene Full Name: RAB2B, member RAS oncogene family
Band: 14q11.2
Quick LinksEntrez ID:84932; OMIM: 607466; Uniprot ID:RAB2B_HUMAN; ENSEMBL ID: ENSG00000129472; HGNC ID: 20246
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst0 / 623190 
fetus12 / 56401221
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult70 / 193912136
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma6 / 8282372
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor7 / 26384526
glioma3 / 10688328
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia4 / 9725041
normal105 / 336030731
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer6 / 10268058
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood3 / 12347824
bone3 / 7165541
bone marrow0 / 488010 
brain38 / 110098934
cervix1 / 4817120
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye6 / 21105428
heart2 / 8962622
intestine7 / 23447229
kidney2 / 2117779
larynx1 / 2414541
liver5 / 20774324
lung10 / 33697429
lymph0 / 442700 
lymph node1 / 9161010
mammary gland4 / 15327126
mouth0 / 670520 
muscle2 / 10771518
nerve1 / 1576863
ovary2 / 10205119
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta8 / 28082528
prostate8 / 18934542
salivary gland0 / 201550 
skin6 / 21057428
spleen0 / 539520 
stomach0 / 966190 
testis11 / 33044233
thymus2 / 8113124
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus4 / 23287817
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1376_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.13 ± 0.43
Basal Forebrain7.03 ± 0.35
Basal Part of Pons7.26 ± 0.21
Cerebellar Cortex7.07 ± 0.29
Cerebellar Nuclei7.16 ± 0.41
Claustrum7.05 ± 0.42
Epithalamus6.88 ± 0.47
Frontal Lobe7.19 ± 0.4
Globus Pallidus6.93 ± 0.29
Hypothalamus7.44 ± 0.4
Insula7.08 ± 0.43
Limbic Lobe7.09 ± 0.48
Mesencephalon7.13 ± 0.34
Myelencephalon7.05 ± 0.41
Occipital Lobe7.05 ± 0.4
Parietal Lobe7.16 ± 0.38
Pontine Tegmentum7.16 ± 0.38
Striatum7.13 ± 0.4
Subthalamus7.19 ± 0.38
Temporal Lobe7.08 ± 0.46
Thalamus7.12 ± 0.28
White Matter7.47 ± 0.32
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rab2bCBCerebellum1.25
1.47
Rab2bCTXCerebral cortex0.49
0.46
Rab2bHIPHippocampal region0.71
0.75
Rab2bHPFHippocampal formation0.7
0.74
Rab2bHYHypothalamus0.05
0.04
Rab2bLSXLateral septal complex0.06
0.13
Rab2bMBMidbrain0.32
0.44
Rab2bMYMedulla2.13
2.59
Rab2bOLFOlfactory bulb1.62
2.23
Rab2bPPons1.73
2.29
Rab2bPALPallidum0.42
0.36
Rab2bRHPRetrohippocampal region0.68
0.74
Rab2bsAMYStriatum-like amygdalar nuclei0.36
0.25
Rab2bSTRStriatum0.21
0.19
Rab2bSTRdStriatum dorsal region0.19
0.18
Rab2bSTRvStriatum ventral region0.27
0.22
Rab2bTHThalamus0.18
0.12
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00002050 12 140 151 EHGLIFMETSAK Peptide Atlas
RAB2B_HUMAN_19 11 19 29 SCLLLQFTDKR PRIDE
RAB2B_HUMAN_56 13 56 68 LQIWDTAGQESFR PRIDE
RAB2B_HUMAN_77 14 77 90 GAAGALLVYDITRR PRIDE
RAB2B_HUMAN_8 11 8 18 YIIIGDTGVGK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018