AutismKB 2.0

Annotation Detail for C8orf76


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Basic Information Top
Gene Symbol:C8orf76 ( FLJ14825,MGC9784 )
Gene Full Name: chromosome 8 open reading frame 76
Band: 8q24.13
Quick LinksEntrez ID:84933; OMIM: NA; Uniprot ID:CH076_HUMAN; ENSEMBL ID: ENSG00000189376; HGNC ID: 25924
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst4 / 6231964
fetus23 / 56401240
neonate0 / 310970 
infant1 / 2362042
juvenile3 / 5555653
adult45 / 193912123
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor5 / 26384518
glioma2 / 10688318
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia4 / 9584241
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal87 / 336030725
ovarian tumor4 / 7668252
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood4 / 12347832
bone5 / 7165569
bone marrow0 / 488010 
brain10 / 11009899
cervix1 / 4817120
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye10 / 21105447
heart5 / 8962655
intestine6 / 23447225
kidney8 / 21177737
larynx0 / 241450 
liver7 / 20774333
lung10 / 33697429
lymph0 / 442700 
lymph node6 / 9161065
mammary gland2 / 15327113
mouth2 / 6705229
muscle4 / 10771537
nerve0 / 157680 
ovary4 / 10205139
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta11 / 28082539
prostate3 / 18934515
salivary gland0 / 201550 
skin8 / 21057437
spleen1 / 5395218
stomach5 / 9661951
testis1 / 3304423
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_2286_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.31 ± 0.52
Basal Forebrain6.28 ± 0.17
Basal Part of Pons6.39 ± 0.46
Cerebellar Cortex6.83 ± 0.22
Cerebellar Nuclei6.39 ± 0.43
Claustrum6.23 ± 0.59
Epithalamus6.8 ± 0.51
Frontal Lobe6.64 ± 0.31
Globus Pallidus6.02 ± 0.39
Hypothalamus6.45 ± 0.34
Insula6.64 ± 0.3
Limbic Lobe6.56 ± 0.41
Mesencephalon6.56 ± 0.4
Myelencephalon6.48 ± 0.43
Occipital Lobe6.16 ± 0.31
Parietal Lobe6.48 ± 0.37
Pontine Tegmentum6.55 ± 0.4
Striatum6.37 ± 0.35
Subthalamus6.31 ± 0.97
Temporal Lobe6.59 ± 0.34
Thalamus6.39 ± 0.29
White Matter6.07 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
9130401M01RikCBCerebellum5.57
6.57
9130401M01RikCTXCerebral cortex1.02
0.94
9130401M01RikHIPHippocampal region1.5
2.04
9130401M01RikHPFHippocampal formation1.39
1.68
9130401M01RikHYHypothalamus0.19
0.25
9130401M01RikLSXLateral septal complex0.05
0
9130401M01RikMBMidbrain1.98
3.06
9130401M01RikMYMedulla0.95
0.97
9130401M01RikOLFOlfactory bulb2.51
1.95
9130401M01RikPPons0.26
0.47
9130401M01RikPALPallidum0.12
0.1
9130401M01RikRHPRetrohippocampal region1.22
1.22
9130401M01RiksAMYStriatum-like amygdalar nuclei0.13
0.18
9130401M01RikSTRStriatum0.27
0.27
9130401M01RikSTRdStriatum dorsal region0.31
0.3
9130401M01RikSTRvStriatum ventral region0.21
0.23
9130401M01RikTHThalamus1.18
2.01
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018