AutismKB 2.0

Annotation Detail for CGNL1


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Basic Information Top
Gene Symbol:CGNL1 ( FLJ14957,JACOP,KIAA1749,MGC138254 )
Gene Full Name: cingulin-like 1
Band: 15q21.3
Quick LinksEntrez ID:84952; OMIM: 607856; Uniprot ID:CGNL1_HUMAN; ENSEMBL ID: ENSG00000128849; HGNC ID: 25931
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst5 / 6231980
fetus30 / 56401253
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult66 / 193912134
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor4 / 26384515
glioma0 / 1068830 
head and neck tumor5 / 13630236
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor6 / 9635962
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal109 / 336030732
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain9 / 11009898
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye7 / 21105433
heart5 / 8962655
intestine1 / 2344724
kidney13 / 21177761
larynx0 / 241450 
liver6 / 20774328
lung9 / 33697426
lymph0 / 442700 
lymph node0 / 916100 
mammary gland5 / 15327132
mouth0 / 670520 
muscle5 / 10771546
nerve0 / 157680 
ovary1 / 1020519
pancreas1 / 2148124
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta17 / 28082560
prostate4 / 18934521
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach1 / 9661910
testis12 / 33044236
thymus1 / 8113112
thyroid8 / 47473168
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus5 / 23287821
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P135319
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.89 ± 0.4
Basal Forebrain7.16 ± 0.48
Basal Part of Pons6.24 ± 0.33
Cerebellar Cortex6.37 ± 0.22
Cerebellar Nuclei7.35 ± 0.39
Claustrum7.07 ± 0.43
Epithalamus7.18 ± 0.38
Frontal Lobe6.75 ± 0.49
Globus Pallidus8.38 ± 0.46
Hypothalamus6.91 ± 0.35
Insula6.68 ± 0.53
Limbic Lobe6.6 ± 0.61
Mesencephalon7.12 ± 0.54
Myelencephalon6.99 ± 0.54
Occipital Lobe7.05 ± 0.55
Parietal Lobe6.9 ± 0.46
Pontine Tegmentum7.01 ± 0.44
Striatum7.51 ± 0.43
Subthalamus7.03 ± 0.64
Temporal Lobe6.7 ± 0.39
Thalamus7.11 ± 0.4
White Matter7.37 ± 0.44
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cgnl1CBCerebellum7.79
9.44
Cgnl1CTXCerebral cortex12.92
9.03
Cgnl1HIPHippocampal region10.01
9.84
Cgnl1HPFHippocampal formation12.22
10.93
Cgnl1HYHypothalamus6.75
5.52
Cgnl1LSXLateral septal complex3.85
2.83
Cgnl1MBMidbrain11.49
13.51
Cgnl1MYMedulla14.71
24.15
Cgnl1OLFOlfactory bulb9.32
7.93
Cgnl1PPons15.26
20.87
Cgnl1PALPallidum6.95
8.08
Cgnl1RHPRetrohippocampal region17.86
13.95
Cgnl1sAMYStriatum-like amygdalar nuclei8.68
8.34
Cgnl1STRStriatum5.02
4.75
Cgnl1STRdStriatum dorsal region3.89
3.7
Cgnl1STRvStriatum ventral region6.21
5.69
Cgnl1THThalamus11.12
12.24
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018