AutismKB 2.0

Annotation Detail for UBASH3B


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:UBASH3B ( KIAA1959,MGC15437,STS-1,STS1,p70 )
Gene Full Name: ubiquitin associated and SH3 domain containing B
Band: 11q24.1
Quick LinksEntrez ID:84959; OMIM: 609201; Uniprot ID:UBS3B_HUMAN; ENSEMBL ID: ENSG00000154127; HGNC ID: 29884
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst0 / 623190 
fetus15 / 56401226
neonate4 / 31097128
infant0 / 236200 
juvenile5 / 5555689
adult65 / 193912133
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor42 / 263845159
glioma3 / 10688328
head and neck tumor2 / 13630214
kidney tumor6 / 6895987
leukemia8 / 9584283
liver tumor13 / 96359134
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal143 / 336030742
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor7 / 12494956
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood5 / 12347840
bone7 / 7165597
bone marrow5 / 48801102
brain51 / 110098946
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus1 / 2020949
eye0 / 2110540 
heart0 / 896260 
intestine4 / 23447217
kidney30 / 211777141
larynx0 / 241450 
liver16 / 20774377
lung17 / 33697450
lymph1 / 4427022
lymph node2 / 9161021
mammary gland2 / 15327113
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta18 / 28082564
prostate0 / 1893450 
salivary gland0 / 201550 
skin16 / 21057475
spleen8 / 53952148
stomach1 / 9661910
testis20 / 33044260
thymus7 / 8113186
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus20 / 23287885
vascular6 / 51780115
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_607_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.48 ± 0.77
Basal Forebrain2.96 ± 0.54
Basal Part of Pons4.09 ± 0.31
Cerebellar Cortex3.9 ± 0.42
Cerebellar Nuclei3.78 ± 0.62
Claustrum3.7 ± 0.94
Epithalamus2.75 ± 0.91
Frontal Lobe3.06 ± 0.79
Globus Pallidus2.37 ± 0.82
Hypothalamus3.36 ± 0.34
Insula2.68 ± 0.57
Limbic Lobe3.03 ± 0.71
Mesencephalon3.31 ± 0.75
Myelencephalon3.16 ± 0.79
Occipital Lobe3.29 ± 0.89
Parietal Lobe3.24 ± 0.72
Pontine Tegmentum2.86 ± 0.66
Striatum2.67 ± 0.69
Subthalamus4.24 ± 0.38
Temporal Lobe3.04 ± 0.79
Thalamus2.76 ± 0.84
White Matter2.45 ± 0.45
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
2810457I06RikCBCerebellum69.54
100
2810457I06RikCTXCerebral cortex39.47
39.25
2810457I06RikHIPHippocampal region41.09
67.93
2810457I06RikHPFHippocampal formation38.84
52.66
2810457I06RikHYHypothalamus23.06
23.58
2810457I06RikLSXLateral septal complex3.77
3.79
2810457I06RikMBMidbrain24.67
27.48
2810457I06RikMYMedulla51.9
69.88
2810457I06RikOLFOlfactory bulb68.07
75.97
2810457I06RikPPons38.3
52.53
2810457I06RikPALPallidum23.09
23.74
2810457I06RikRHPRetrohippocampal region36.76
35.96
2810457I06RiksAMYStriatum-like amygdalar nuclei24.4
22.71
2810457I06RikSTRStriatum14.73
11.44
2810457I06RikSTRdStriatum dorsal region13.95
10.25
2810457I06RikSTRvStriatum ventral region14.8
10.68
2810457I06RikTHThalamus17.36
34.09
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00096542 23 451 473 LVGEALLESNTIIDHVYCSPSLR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018