AutismKB 2.0

Annotation Detail for FBXL20


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Basic Information Top
Gene Symbol:FBXL20 ( DKFZp564O2364,FLJ21037,Fbl2,Fbl20,MGC15482 )
Gene Full Name: F-box and leucine-rich repeat protein 20
Band: 17q12
Quick LinksEntrez ID:84961; OMIM: 609086; Uniprot ID:FXL20_HUMAN; ENSEMBL ID: ENSG00000108306; HGNC ID: 24679
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus26 / 56401246
neonate2 / 3109764
infant0 / 236200 
juvenile1 / 5555617
adult228 / 1939121117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor139 / 941781475
cervical tumor1 / 3436629
chondrosarcoma4 / 8282348
colorectal tumor14 / 114246122
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor2 / 2638457
glioma4 / 10688337
head and neck tumor29 / 136302212
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor2 / 9635920
lung tumor4 / 10312738
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal91 / 336030727
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma4 / 4635686
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood8 / 12347864
bone4 / 7165555
bone marrow0 / 488010 
brain25 / 110098922
cervix1 / 4817120
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye10 / 21105447
heart2 / 8962622
intestine15 / 23447263
kidney2 / 2117779
larynx2 / 2414582
liver3 / 20774314
lung16 / 33697447
lymph1 / 4427022
lymph node6 / 9161065
mammary gland140 / 153271913
mouth26 / 67052387
muscle3 / 10771527
nerve1 / 1576863
ovary5 / 10205148
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate1 / 1893455
salivary gland0 / 201550 
skin4 / 21057418
spleen2 / 5395237
stomach4 / 9661941
testis5 / 33044215
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11546_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.56 ± 0.72
Basal Forebrain4.42 ± 0.33
Basal Part of Pons4.53 ± 0.59
Cerebellar Cortex4.92 ± 0.34
Cerebellar Nuclei4.22 ± 0.55
Claustrum4.51 ± 0.77
Epithalamus4.4 ± 0.35
Frontal Lobe4.59 ± 0.45
Globus Pallidus3.48 ± 0.6
Hypothalamus4.52 ± 1.33
Insula4.57 ± 0.42
Limbic Lobe4.57 ± 0.47
Mesencephalon4.57 ± 0.58
Myelencephalon4.48 ± 0.54
Occipital Lobe4.58 ± 0.56
Parietal Lobe4.64 ± 0.44
Pontine Tegmentum4.6 ± 0.57
Striatum4.11 ± 0.59
Subthalamus4.49 ± 0.37
Temporal Lobe4.66 ± 0.52
Thalamus4.48 ± 0.52
White Matter3.15 ± 1.04
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
FXL20_HUMAN_275 8 275 282 LRILEVAR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018