AutismKB 2.0

Annotation Detail for TOX2


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Basic Information Top
Gene Symbol:TOX2 ( C20orf100,GCX-1,MGC15880,dJ1108D11.2,dJ495O3.1 )
Gene Full Name: TOX high mobility group box family member 2
Band: 20q13.12
Quick LinksEntrez ID:84969; OMIM: 611163; Uniprot ID:TOX2_HUMAN; ENSEMBL ID: ENSG00000124191; HGNC ID: 16095
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus9 / 56401215
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult18 / 19391219
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor5 / 26384518
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal52 / 336030715
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone0 / 716550 
bone marrow0 / 488010 
brain30 / 110098927
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine1 / 2344724
kidney4 / 21177718
larynx0 / 241450 
liver0 / 2077430 
lung12 / 33697435
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate1 / 1893455
salivary gland1 / 2015549
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis6 / 33044218
thymus8 / 8113198
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13736_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.18 ± 0.77
Basal Forebrain6.59 ± 0.29
Basal Part of Pons5.37 ± 0.59
Cerebellar Cortex5.71 ± 0.63
Cerebellar Nuclei6.23 ± 0.67
Claustrum7.03 ± 1.26
Epithalamus5.54 ± 0.86
Frontal Lobe6.61 ± 0.98
Globus Pallidus7.94 ± 0.54
Hypothalamus6.92 ± 1.16
Insula6.26 ± 0.94
Limbic Lobe6.88 ± 1.13
Mesencephalon7.44 ± 0.73
Myelencephalon6.87 ± 1.16
Occipital Lobe7.99 ± 0.83
Parietal Lobe7.25 ± 0.86
Pontine Tegmentum7.16 ± 0.56
Striatum6.82 ± 1.26
Subthalamus7.12 ± 0.22
Temporal Lobe6.61 ± 0.87
Thalamus7.56 ± 0.68
White Matter5.47 ± 0.72
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00071073 14 288 301 IVASMWDSLGEEQK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018