AutismKB 2.0

Annotation Detail for DISP1


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Basic Information Top
Gene Symbol:DISP1 ( DISPA,DKFZp434I0428,FLJ43740,MGC104180,MGC13130,MGC16796 )
Gene Full Name: dispatched homolog 1 (Drosophila)
Band: 1q41
Quick LinksEntrez ID:84976; OMIM: 607502; Uniprot ID:DISP1_HUMAN; ENSEMBL ID: ENSG00000154309; HGNC ID: 19711
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst0 / 623190 
fetus17 / 56401230
neonate1 / 3109732
infant1 / 2362042
juvenile0 / 555560 
adult48 / 193912124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor2 / 11424617
esophageal tumor1 / 1729057
gastrointestinal tumor3 / 11936925
germ cell tumor9 / 26384534
glioma1 / 1068839
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal82 / 336030724
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood2 / 12347816
bone2 / 7165527
bone marrow1 / 4880120
brain26 / 110098923
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus1 / 2020949
eye7 / 21105433
heart0 / 896260 
intestine4 / 23447217
kidney3 / 21177714
larynx0 / 241450 
liver0 / 2077430 
lung9 / 33697426
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth1 / 6705214
muscle8 / 10771574
nerve0 / 157680 
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta10 / 28082535
prostate4 / 18934521
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach2 / 9661920
testis31 / 33044293
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord1 / 1368073
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9443_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.21 ± 1.17
Basal Forebrain3.08 ± 0.41
Basal Part of Pons2.45 ± 0.59
Cerebellar Cortex2.8 ± 1.11
Cerebellar Nuclei2.99 ± 0.68
Claustrum3.43 ± 0.89
Epithalamus2.86 ± 1.08
Frontal Lobe2.71 ± 0.98
Globus Pallidus3.58 ± 0.62
Hypothalamus2.76 ± 0.75
Insula2.66 ± 1.31
Limbic Lobe2.83 ± 0.96
Mesencephalon2.94 ± 0.78
Myelencephalon2.82 ± 0.93
Occipital Lobe2.68 ± 0.76
Parietal Lobe2.91 ± 0.95
Pontine Tegmentum2.95 ± 0.9
Striatum3.06 ± 0.79
Subthalamus3.94 ± 2.06
Temporal Lobe2.56 ± 0.87
Thalamus2.7 ± 0.7
White Matter2.87 ± 0.5
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Disp1CBCerebellum16.67
19.81
Disp1CTXCerebral cortex13.19
9.12
Disp1HIPHippocampal region6.97
6.38
Disp1HPFHippocampal formation7.58
6.8
Disp1HYHypothalamus3.3
2.65
Disp1LSXLateral septal complex6.89
4.86
Disp1MBMidbrain16.96
15.3
Disp1MYMedulla14.91
15.87
Disp1OLFOlfactory bulb25.06
22.72
Disp1PPons15.67
17.3
Disp1PALPallidum7.53
6.18
Disp1RHPRetrohippocampal region8.56
7.14
Disp1sAMYStriatum-like amygdalar nuclei2.83
2.67
Disp1STRStriatum7.69
5.8
Disp1STRdStriatum dorsal region5.68
4.24
Disp1STRvStriatum ventral region16.55
11.6
Disp1THThalamus5.69
4.78
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018