AutismKB 2.0

Annotation Detail for ARHGAP19


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Basic Information Top
Gene Symbol:ARHGAP19 ( DKFZp313K217,MGC138804,MGC138805,MGC14258 )
Gene Full Name: Rho GTPase activating protein 19
Band: 10q24.1
Quick LinksEntrez ID:84986; OMIM: 611587; Uniprot ID:RHG19_HUMAN; ENSEMBL ID: ENSG00000213390; HGNC ID: 23724
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst7 / 62319112
fetus30 / 56401253
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult52 / 193912126
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor17 / 26384564
glioma0 / 1068830 
head and neck tumor8 / 13630258
kidney tumor0 / 689590 
leukemia11 / 95842114
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma2 / 7175527
non-neoplasia2 / 9725020
normal122 / 336030736
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer6 / 10268058
retinoblastoma2 / 4635643
skin tumor2 / 12494916
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites1 / 4001524
bladder1 / 2975733
blood14 / 123478113
bone4 / 7165555
bone marrow0 / 488010 
brain14 / 110098912
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue22 / 215722101
esophagus0 / 202090 
eye7 / 21105433
heart4 / 8962644
intestine0 / 2344720 
kidney3 / 21177714
larynx0 / 241450 
liver0 / 2077430 
lung11 / 33697432
lymph2 / 4427045
lymph node17 / 91610185
mammary gland2 / 15327113
mouth1 / 6705214
muscle3 / 10771527
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta2 / 2808257
prostate8 / 18934542
salivary gland3 / 20155148
skin3 / 21057414
spleen0 / 539520 
stomach0 / 966190 
testis29 / 33044287
thymus4 / 8113149
thyroid3 / 4747363
tonsil2 / 16999117
trachea1 / 5241319
umbilical cord0 / 136800 
uterus9 / 23287838
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212738_at
Cell line Expression level Expression bar
721_B_lymphoblasts151.35
Adipocyte10.1
AdrenalCortex12.9
Adrenalgland10.3
Amygdala11.8
Appendix13.75
AtrioventricularNode17.2
BDCA4+_DentriticCells20.05
Bonemarrow13.65
BronchialEpithelialCells12.5
CD105+_Endothelial84
CD14+_Monocytes14.45
CD19+_BCells(neg._sel.)19.1
CD33+_Myeloid38.95
CD34+48.3
CD4+_Tcells15.45
CD56+_NKCells21.9
CD71+_EarlyErythroid120.2
CD8+_Tcells17.2
CardiacMyocytes17.85
Caudatenucleus10.3
Cerebellum9.1
CerebellumPeduncles14.6
CiliaryGanglion10
CingulateCortex12.8
Colorectaladenocarcinoma12.6
DorsalRootGanglion35.2
FetalThyroid12.4
Fetalbrain12.3
Fetalliver11
Fetallung10.2
GlobusPallidus9.4
Heart15.7
Hypothalamus13.75
Kidney10.25
Leukemia_chronicMyelogenousK-56217.1
Leukemia_promyelocytic-HL-6013.45
Leukemialymphoblastic(MOLT-4)32.9
Liver16.35
Lung13.95
Lymphnode11.4
Lymphoma_burkitts(Daudi)18.5
Lymphoma_burkitts(Raji)19.15
MedullaOblongata10.45
OccipitalLobe10.2
OlfactoryBulb142
Ovary8.8
Pancreas10
PancreaticIslet13.75
ParietalLobe13.2
Pituitary14.55
Placenta11
Pons12.4
PrefrontalCortex15.6
Prostate14.85
Salivarygland10.1
SkeletalMuscle14.05
Skin10.05
SmoothMuscle12.25
Spinalcord13.95
SubthalamicNucleus12
SuperiorCervicalGanglion16.1
TemporalLobe11.8
Testis18.9
TestisGermCell21.8
TestisIntersitial17.25
TestisLeydigCell17.2
TestisSeminiferousTubule14.85
Thalamus12.25
Thymus18.1
Thyroid15.15
Tongue12.6
Tonsil12.7
Trachea8.55
TrigeminalGanglion18.3
Uterus10.35
UterusCorpus12.2
WholeBlood21.95
Wholebrain8.95
colon17.4
pineal_day16.16
pineal_night15.28
retina16.125
small_intestine13
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P1387
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.87 ± 0.74
Basal Forebrain3.02 ± 0.31
Basal Part of Pons2.42 ± 0.5
Cerebellar Cortex2.91 ± 0.65
Cerebellar Nuclei2.87 ± 0.83
Claustrum3.08 ± 0.51
Epithalamus3.05 ± 0.52
Frontal Lobe2.85 ± 0.65
Globus Pallidus3.53 ± 0.44
Hypothalamus2.64 ± 0.56
Insula2.75 ± 0.64
Limbic Lobe2.77 ± 0.54
Mesencephalon2.97 ± 0.74
Myelencephalon2.96 ± 0.62
Occipital Lobe2.97 ± 0.5
Parietal Lobe2.82 ± 0.64
Pontine Tegmentum2.94 ± 0.62
Striatum3.02 ± 0.58
Subthalamus3.01 ± 0.23
Temporal Lobe2.71 ± 0.66
Thalamus3.05 ± 0.57
White Matter4.1 ± 0.56
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Arhgap19CBCerebellum1.41
1.55
Arhgap19CTXCerebral cortex4.93
3
Arhgap19HIPHippocampal region2.06
2.2
Arhgap19HPFHippocampal formation2.16
1.86
Arhgap19HYHypothalamus0.84
0.78
Arhgap19LSXLateral septal complex8.57
8.12
Arhgap19MBMidbrain1.69
1.89
Arhgap19MYMedulla0.77
0.71
Arhgap19OLFOlfactory bulb3.08
1.73
Arhgap19PPons0.62
0.38
Arhgap19PALPallidum2.03
1.62
Arhgap19RHPRetrohippocampal region2.5
1.51
Arhgap19sAMYStriatum-like amygdalar nuclei6.74
6.91
Arhgap19STRStriatum3.16
2.22
Arhgap19STRdStriatum dorsal region2.11
1
Arhgap19STRvStriatum ventral region1.27
0.51
Arhgap19THThalamus1.81
1.57
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00502186 19 356 374 VDSCPHQEETQHHTEEALR Peptide Atlas
RHG19_HUMAN_2 13 2 14 ATEAQSEGEVPAR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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