AutismKB 2.0

Annotation Detail for TMEM141


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Basic Information Top
Gene Symbol:TMEM141 ( MGC14141,RP11-216L13.7 )
Gene Full Name: transmembrane protein 141
Band: 9q34.3
Quick LinksEntrez ID:85014; OMIM: NA; Uniprot ID:TM141_HUMAN; ENSEMBL ID: ENSG00000213213; HGNC ID: 28211
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst0 / 623190 
fetus17 / 56401230
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult88 / 193912145
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor12 / 94178127
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor9 / 26384534
glioma5 / 10688346
head and neck tumor2 / 13630214
kidney tumor9 / 68959130
leukemia0 / 958420 
liver tumor4 / 9635941
lung tumor8 / 10312777
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal90 / 336030726
ovarian tumor2 / 7668226
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer21 / 102680204
retinoblastoma0 / 463560 
skin tumor17 / 124949136
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood2 / 12347816
bone2 / 7165527
bone marrow0 / 488010 
brain17 / 110098915
cervix1 / 4817120
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye17 / 21105480
heart2 / 8962622
intestine19 / 23447281
kidney11 / 21177751
larynx0 / 241450 
liver6 / 20774328
lung19 / 33697456
lymph1 / 4427022
lymph node1 / 9161010
mammary gland12 / 15327178
mouth0 / 670520 
muscle3 / 10771527
nerve0 / 157680 
ovary2 / 10205119
pancreas17 / 21481279
parathyroid7 / 20539340
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta12 / 28082542
prostate35 / 189345184
salivary gland3 / 20155148
skin17 / 21057480
spleen0 / 539520 
stomach4 / 9661941
testis3 / 3304429
thymus3 / 8113136
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1105_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.06 ± 0.26
Basal Forebrain8.16 ± 0.3
Basal Part of Pons8.5 ± 0.26
Cerebellar Cortex8.04 ± 0.23
Cerebellar Nuclei8.66 ± 0.26
Claustrum8.1 ± 0.28
Epithalamus7.77 ± 0.22
Frontal Lobe8.34 ± 0.36
Globus Pallidus8.52 ± 0.38
Hypothalamus8.03 ± 0.34
Insula8.22 ± 0.26
Limbic Lobe8.09 ± 0.43
Mesencephalon8.28 ± 0.48
Myelencephalon8.17 ± 0.4
Occipital Lobe7.78 ± 0.27
Parietal Lobe8.17 ± 0.36
Pontine Tegmentum8.1 ± 0.24
Striatum7.77 ± 0.25
Subthalamus8.44 ± 0.12
Temporal Lobe8.27 ± 0.33
Thalamus8.31 ± 0.28
White Matter8.65 ± 0.09
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018