AutismKB 2.0

Annotation Detail for ITGA10


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Basic Information Top
Gene Symbol:ITGA10 ( PRO827 )
Gene Full Name: integrin, alpha 10
Band: 1q21.1
Quick LinksEntrez ID:8515; OMIM: 604042; Uniprot ID:ITA10_HUMAN; ENSEMBL ID: ENSG00000143127; HGNC ID: 6135
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult30 / 193912115
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia8 / 9725082
normal47 / 336030713
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone5 / 7165569
bone marrow0 / 488010 
brain13 / 110098911
cervix0 / 481710 
connective tissue10 / 14925566
ear2 / 16212123
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye0 / 2110540 
heart1 / 8962611
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung2 / 3369745
lymph0 / 442700 
lymph node2 / 9161021
mammary gland2 / 15327113
mouth0 / 670520 
muscle11 / 107715102
nerve0 / 157680 
ovary0 / 1020510 
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate2 / 18934510
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach1 / 9661910
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea7 / 52413133
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206766_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.65
Adipocyte5.8
AdrenalCortex6.2
Adrenalgland4.95
Amygdala6.25
Appendix6.5
AtrioventricularNode18.6
BDCA4+_DentriticCells6.6
Bonemarrow5.75
BronchialEpithelialCells5.7
CD105+_Endothelial5.85
CD14+_Monocytes6.25
CD19+_BCells(neg._sel.)6.1
CD33+_Myeloid7.65
CD34+7.7
CD4+_Tcells6.05
CD56+_NKCells6.65
CD71+_EarlyErythroid5.4
CD8+_Tcells5.6
CardiacMyocytes7.2
Caudatenucleus5.25
Cerebellum4.7
CerebellumPeduncles6.6
CiliaryGanglion11.2
CingulateCortex6.2
Colorectaladenocarcinoma5.75
DorsalRootGanglion11.35
FetalThyroid5.8
Fetalbrain5.9
Fetalliver5.1
Fetallung5.1
GlobusPallidus4.35
Heart7.8
Hypothalamus6.5
Kidney4.85
Leukemia_chronicMyelogenousK-5625.3
Leukemia_promyelocytic-HL-605.1
Leukemialymphoblastic(MOLT-4)4.75
Liver7.55
Lung6.3
Lymphnode5.1
Lymphoma_burkitts(Daudi)7.4
Lymphoma_burkitts(Raji)7.95
MedullaOblongata5.4
OccipitalLobe5.3
OlfactoryBulb33.8
Ovary4.05
Pancreas4.65
PancreaticIslet6.15
ParietalLobe6.25
Pituitary6.9
Placenta6
Pons6.45
PrefrontalCortex7.45
Prostate6.7
Salivarygland4.95
SkeletalMuscle7.95
Skin4.65
SmoothMuscle6.6
Spinalcord6.3
SubthalamicNucleus5.2
SuperiorCervicalGanglion17.45
TemporalLobe5.25
Testis5.25
TestisGermCell5
TestisIntersitial4.95
TestisLeydigCell5.8
TestisSeminiferousTubule5.05
Thalamus5.9
Thymus4.5
Thyroid7.35
Tongue7.65
Tonsil5.65
Trachea9.45
TrigeminalGanglion12.9
Uterus4.7
UterusCorpus6.2
WholeBlood6.5
Wholebrain5.05
colon5.9
pineal_day7.14
pineal_night7.16
retina7.55
small_intestine5.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_2029_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.04 ± 1
Basal Forebrain1.59 ± 0.17
Basal Part of Pons1.48 ± 0.63
Cerebellar Cortex1.55 ± 0.69
Cerebellar Nuclei1.88 ± 0.7
Claustrum2.48 ± 0.87
Epithalamus1.27 ± 0.74
Frontal Lobe1.42 ± 0.56
Globus Pallidus2.51 ± 0.54
Hypothalamus1.75 ± 0.83
Insula1.65 ± 0.85
Limbic Lobe1.58 ± 0.65
Mesencephalon1.74 ± 0.66
Myelencephalon1.64 ± 0.66
Occipital Lobe1.86 ± 0.72
Parietal Lobe1.5 ± 0.64
Pontine Tegmentum1.66 ± 0.64
Striatum1.84 ± 0.63
Subthalamus1.7 ± 0.63
Temporal Lobe1.54 ± 0.64
Thalamus1.6 ± 0.57
White Matter1.97 ± 0.18
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Itga10CBCerebellum1.84
1.74
Itga10CTXCerebral cortex2.02
0.95
Itga10HIPHippocampal region0.48
0.47
Itga10HPFHippocampal formation0.58
0.48
Itga10HYHypothalamus1.44
0.82
Itga10LSXLateral septal complex0.64
0.27
Itga10MBMidbrain1.67
1.02
Itga10MYMedulla5.07
2.63
Itga10OLFOlfactory bulb5.79
4.46
Itga10PPons3.17
1.5
Itga10PALPallidum0.93
0.3
Itga10RHPRetrohippocampal region0.72
0.44
Itga10sAMYStriatum-like amygdalar nuclei1.6
0.92
Itga10STRStriatum0.96
0.45
Itga10STRdStriatum dorsal region0.33
0.16
Itga10STRvStriatum ventral region3.39
1.4
Itga10THThalamus0.38
0.39
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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