AutismKB 2.0

Annotation Detail for IFITM1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:IFITM1 ( 9-27,CD225,IFI17,LEU13 )
Gene Full Name: interferon induced transmembrane protein 1 (9-27)
Band: 11p15.5
Quick LinksEntrez ID:8519; OMIM: 604456; Uniprot ID:IFM1_HUMAN; ENSEMBL ID: ENSG00000185885; HGNC ID: 5412
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst12 / 62319192
fetus23 / 56401240
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult240 / 1939121123
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor4 / 12794312
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor6 / 34366174
chondrosarcoma13 / 82823156
colorectal tumor12 / 114246105
esophageal tumor0 / 172900 
gastrointestinal tumor11 / 11936992
germ cell tumor6 / 26384522
glioma0 / 1068830 
head and neck tumor8 / 13630258
kidney tumor3 / 6895943
leukemia19 / 95842198
liver tumor15 / 96359155
lung tumor3 / 10312729
lymphoma3 / 7175541
non-neoplasia7 / 9725071
normal298 / 336030788
ovarian tumor28 / 76682365
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor21 / 125191167
uterine tumor20 / 90257221
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland4 / 33197120
ascites7 / 40015174
bladder0 / 297570 
blood18 / 123478145
bone13 / 71655181
bone marrow45 / 48801922
brain20 / 110098918
cervix6 / 48171124
connective tissue23 / 149255154
ear1 / 1621261
embryonic tissue55 / 215722254
esophagus0 / 202090 
eye27 / 211054127
heart3 / 8962633
intestine19 / 23447281
kidney6 / 21177728
larynx5 / 24145207
liver19 / 20774391
lung19 / 33697456
lymph0 / 442700 
lymph node8 / 9161087
mammary gland10 / 15327165
mouth3 / 6705244
muscle4 / 10771537
nerve1 / 1576863
ovary30 / 102051293
pancreas15 / 21481269
parathyroid3 / 20539146
pharynx31 / 41328750
pituitary gland1 / 1658560
placenta10 / 28082535
prostate20 / 189345105
salivary gland16 / 20155793
skin1 / 2105744
spleen4 / 5395274
stomach7 / 9661972
testis6 / 33044218
thymus2 / 8113124
thyroid2 / 4747342
tonsil1 / 1699958
trachea1 / 5241319
umbilical cord0 / 136800 
uterus40 / 232878171
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214022_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts1467.15
Adipocyte204.8
AdrenalCortex115.25
Adrenalgland246
Amygdala51.1
Appendix559.45
AtrioventricularNode196.65
BDCA4+_DentriticCells171.8
Bonemarrow312.3
BronchialEpithelialCells116.4
CD105+_Endothelial45.55
CD14+_Monocytes63.3
CD19+_BCells(neg._sel.)247.85
CD33+_Myeloid45.9
CD34+24.4
CD4+_Tcells1677.2
CD56+_NKCells2309.75
CD71+_EarlyErythroid3.65
CD8+_Tcells1424.15
CardiacMyocytes15.05
Caudatenucleus33.85
Cerebellum19.95
CerebellumPeduncles28.1
CiliaryGanglion162.15
CingulateCortex32.05
Colorectaladenocarcinoma134.75
DorsalRootGanglion136.75
FetalThyroid185.25
Fetalbrain16.8
Fetalliver5.45
Fetallung288.5
GlobusPallidus15.8
Heart1618.65
Hypothalamus118.95
Kidney94.15
Leukemia_chronicMyelogenousK-5621871.75
Leukemia_promyelocytic-HL-603.95
Leukemialymphoblastic(MOLT-4)198.9
Liver759.7
Lung1187.3
Lymphnode722.55
Lymphoma_burkitts(Daudi)24.8
Lymphoma_burkitts(Raji)6.2
MedullaOblongata28.25
OccipitalLobe22.4
OlfactoryBulb605.65
Ovary612.55
Pancreas420.8
PancreaticIslet415.55
ParietalLobe23.4
Pituitary75
Placenta391.95
Pons19.3
PrefrontalCortex301.75
Prostate558.65
Salivarygland235.5
SkeletalMuscle34
Skin142.7
SmoothMuscle54.45
Spinalcord297.25
SubthalamicNucleus17.55
SuperiorCervicalGanglion95.7
TemporalLobe69.8
Testis198.9
TestisGermCell152.15
TestisIntersitial49.65
TestisLeydigCell95.05
TestisSeminiferousTubule105.15
Thalamus60.15
Thymus790.7
Thyroid181.2
Tongue176.1
Tonsil612.95
Trachea295.5
TrigeminalGanglion229.65
Uterus705.35
UterusCorpus281.9
WholeBlood2378.85
Wholebrain47.05
colon490.25
pineal_day73.8
pineal_night103.94
retina778.575
small_intestine942.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9073_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.52 ± 0.5
Basal Forebrain9.13 ± 0.13
Basal Part of Pons8.52 ± 0.43
Cerebellar Cortex8.64 ± 0.21
Cerebellar Nuclei9.51 ± 0.27
Claustrum8.1 ± 0.5
Epithalamus9.51 ± 0.48
Frontal Lobe9.04 ± 0.46
Globus Pallidus10.24 ± 0.38
Hypothalamus9.09 ± 0.59
Insula9.05 ± 0.29
Limbic Lobe8.84 ± 0.54
Mesencephalon9.25 ± 0.52
Myelencephalon9.2 ± 0.57
Occipital Lobe9.36 ± 0.54
Parietal Lobe8.89 ± 0.47
Pontine Tegmentum9.24 ± 0.5
Striatum10.05 ± 0.47
Subthalamus9.28 ± 0.39
Temporal Lobe8.99 ± 0.4
Thalamus9.36 ± 0.39
White Matter8.9 ± 1.12
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ifitm1CBCerebellum2.68
4.8
Ifitm1CTXCerebral cortex0.71
0.97
Ifitm1HIPHippocampal region0.75
0.75
Ifitm1HPFHippocampal formation0.81
0.73
Ifitm1HYHypothalamus1.29
1.6
Ifitm1LSXLateral septal complex0.22
1.25
Ifitm1MBMidbrain2.03
3.13
Ifitm1MYMedulla13.41
19.89
Ifitm1OLFOlfactory bulb1.44
1.88
Ifitm1PPons3.62
5.94
Ifitm1PALPallidum0.61
0.95
Ifitm1RHPRetrohippocampal region0.9
0.7
Ifitm1sAMYStriatum-like amygdalar nuclei3.09
3.7
Ifitm1STRStriatum0.95
1.21
Ifitm1STRdStriatum dorsal region0.26
0.23
Ifitm1STRvStriatum ventral region3.14
4.46
Ifitm1THThalamus2.01
2.34
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
IFM1_HUMAN_67 16 67 82 MVGDVTGAQAYASTAK PRIDE
PAp00075019 16 73 88 MVGDVTGAQAYASTAK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved