AutismKB 2.0

Annotation Detail for DGKD


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Basic Information Top
Gene Symbol:DGKD ( DGKdelta,FLJ26930,KIAA0145,dgkd-2 )
Gene Full Name: diacylglycerol kinase, delta 130kDa
Band: 2q37.1
Quick LinksEntrez ID:8527; OMIM: 601826; Uniprot ID:DGKD_HUMAN; ENSEMBL ID: ENSG00000077044; HGNC ID: 2851
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst4 / 6231964
fetus22 / 56401239
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult79 / 193912140
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor16 / 114246140
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor11 / 26384541
glioma4 / 10688337
head and neck tumor5 / 13630236
kidney tumor5 / 6895972
leukemia9 / 9584293
liver tumor1 / 9635910
lung tumor13 / 103127126
lymphoma12 / 71755167
non-neoplasia3 / 9725030
normal123 / 336030736
ovarian tumor0 / 766820 
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer4 / 10268038
retinoblastoma3 / 4635664
skin tumor2 / 12494916
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites0 / 400150 
bladder2 / 2975767
blood6 / 12347848
bone7 / 7165597
bone marrow0 / 488010 
brain31 / 110098928
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye14 / 21105466
heart1 / 8962611
intestine20 / 23447285
kidney8 / 21177737
larynx2 / 2414582
liver5 / 20774324
lung19 / 33697456
lymph8 / 44270180
lymph node23 / 91610251
mammary gland4 / 15327126
mouth1 / 6705214
muscle7 / 10771564
nerve1 / 1576863
ovary0 / 1020510 
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate6 / 18934531
salivary gland1 / 2015549
skin2 / 2105749
spleen0 / 539520 
stomach7 / 9661972
testis11 / 33044233
thymus4 / 8113149
thyroid2 / 4747342
tonsil2 / 16999117
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208072_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts91.85
Adipocyte47
AdrenalCortex55.25
Adrenalgland22.75
Amygdala66.8
Appendix55.5
AtrioventricularNode45.5
BDCA4+_DentriticCells184.85
Bonemarrow54.25
BronchialEpithelialCells42.3
CD105+_Endothelial76.4
CD14+_Monocytes115.5
CD19+_BCells(neg._sel.)524.75
CD33+_Myeloid207.55
CD34+99.35
CD4+_Tcells354.95
CD56+_NKCells292.2
CD71+_EarlyErythroid34.45
CD8+_Tcells410.4
CardiacMyocytes38.35
Caudatenucleus65.05
Cerebellum156.45
CerebellumPeduncles178.7
CiliaryGanglion37.2
CingulateCortex41.5
Colorectaladenocarcinoma61.9
DorsalRootGanglion37.75
FetalThyroid60.4
Fetalbrain108.55
Fetalliver27.2
Fetallung61.95
GlobusPallidus37.15
Heart67.55
Hypothalamus82.7
Kidney23.35
Leukemia_chronicMyelogenousK-56264.5
Leukemia_promyelocytic-HL-60122.35
Leukemialymphoblastic(MOLT-4)56.25
Liver74.2
Lung96.7
Lymphnode104.75
Lymphoma_burkitts(Daudi)289.05
Lymphoma_burkitts(Raji)337.7
MedullaOblongata56.9
OccipitalLobe39.15
OlfactoryBulb38.9
Ovary30.45
Pancreas37.45
PancreaticIslet31.35
ParietalLobe59.8
Pituitary52.65
Placenta52.95
Pons49
PrefrontalCortex67.25
Prostate116.85
Salivarygland33.75
SkeletalMuscle122.8
Skin18.3
SmoothMuscle37.2
Spinalcord68.1
SubthalamicNucleus47.6
SuperiorCervicalGanglion40.9
TemporalLobe38.05
Testis135.35
TestisGermCell129.6
TestisIntersitial95.85
TestisLeydigCell73.1
TestisSeminiferousTubule97.85
Thalamus49.2
Thymus61.55
Thyroid79.05
Tongue47.35
Tonsil76.8
Trachea24.05
TrigeminalGanglion38.35
Uterus49.95
UterusCorpus58.05
WholeBlood146.25
Wholebrain52.15
colon54.6
pineal_day79.84
pineal_night87.82
retina79.525
small_intestine75.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8404_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.47 ± 0.74
Basal Forebrain2.67 ± 0.56
Basal Part of Pons3.06 ± 0.5
Cerebellar Cortex3.73 ± 0.4
Cerebellar Nuclei2.98 ± 0.5
Claustrum3.5 ± 0.7
Epithalamus2.62 ± 0.63
Frontal Lobe3 ± 0.74
Globus Pallidus3.26 ± 0.76
Hypothalamus3.01 ± 0.71
Insula3.31 ± 0.51
Limbic Lobe3.26 ± 0.69
Mesencephalon3.14 ± 0.88
Myelencephalon3.16 ± 0.75
Occipital Lobe3.23 ± 0.76
Parietal Lobe3.18 ± 0.67
Pontine Tegmentum3.14 ± 0.73
Striatum2.87 ± 0.72
Subthalamus3.47 ± 0.19
Temporal Lobe3.09 ± 0.67
Thalamus3.03 ± 0.62
White Matter3.27 ± 0.44
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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