AutismKB 2.0

Annotation Detail for PPIL4


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PPIL4 ( HDCME13P )
Gene Full Name: peptidylprolyl isomerase (cyclophilin)-like 4
Band: 6q25.1
Quick LinksEntrez ID:85313; OMIM: 607609; Uniprot ID:PPIL4_HUMAN; ENSEMBL ID: ENSG00000131013; HGNC ID: 15702
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst1 / 6231916
fetus6 / 56401210
neonate1 / 3109732
infant0 / 236200 
juvenile2 / 5555635
adult48 / 193912124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor4 / 26384515
glioma1 / 1068839
head and neck tumor4 / 13630229
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal84 / 336030724
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone4 / 7165555
bone marrow1 / 4880120
brain19 / 110098917
cervix0 / 481710 
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye6 / 21105428
heart4 / 8962644
intestine11 / 23447246
kidney4 / 21177718
larynx1 / 2414541
liver6 / 20774328
lung6 / 33697417
lymph0 / 442700 
lymph node1 / 9161010
mammary gland1 / 1532716
mouth1 / 6705214
muscle5 / 10771546
nerve1 / 1576863
ovary1 / 1020519
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx6 / 41328145
pituitary gland1 / 1658560
placenta3 / 28082510
prostate5 / 18934526
salivary gland0 / 201550 
skin2 / 2105749
spleen1 / 5395218
stomach5 / 9661951
testis6 / 33044218
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord1 / 1368073
uterus6 / 23287825
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7683_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.95 ± 0.32
Basal Forebrain7.64 ± 0.21
Basal Part of Pons7.28 ± 0.25
Cerebellar Cortex7.45 ± 0.3
Cerebellar Nuclei7.16 ± 0.12
Claustrum7.89 ± 0.32
Epithalamus7.96 ± 0.34
Frontal Lobe7.49 ± 0.32
Globus Pallidus7.8 ± 0.2
Hypothalamus7.68 ± 0.2
Insula7.66 ± 0.32
Limbic Lobe7.69 ± 0.32
Mesencephalon7.62 ± 0.33
Myelencephalon7.54 ± 0.35
Occipital Lobe7.61 ± 0.3
Parietal Lobe7.55 ± 0.34
Pontine Tegmentum7.57 ± 0.37
Striatum7.79 ± 0.26
Subthalamus7.61 ± 0.21
Temporal Lobe7.53 ± 0.33
Thalamus7.33 ± 0.26
White Matter8.12 ± 0.1
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ppil4CBCerebellum2.93
3.31
Ppil4CTXCerebral cortex1.71
1.31
Ppil4HIPHippocampal region3.03
3.34
Ppil4HPFHippocampal formation2.69
2.53
Ppil4HYHypothalamus0.2
0.2
Ppil4LSXLateral septal complex0.09
0.1
Ppil4MBMidbrain1.73
2.48
Ppil4MYMedulla1.4
1.89
Ppil4OLFOlfactory bulb3.89
3.8
Ppil4PPons0.82
0.82
Ppil4PALPallidum0.17
0.14
Ppil4RHPRetrohippocampal region2.3
1.7
Ppil4sAMYStriatum-like amygdalar nuclei0.23
0.33
Ppil4STRStriatum1.62
1.53
Ppil4STRdStriatum dorsal region2.19
2.19
Ppil4STRvStriatum ventral region1.25
0.84
Ppil4THThalamus0.64
0.63
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00003900 14 34 47 IKYYNYCLIHNVQR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018