AutismKB 2.0

Annotation Detail for PAQR8


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Basic Information Top
Gene Symbol:PAQR8 ( C6orf33,FLJ32521,FLJ46206,LMPB1,MPRB )
Gene Full Name: progestin and adipoQ receptor family member VIII
Band: 6p12.2
Quick LinksEntrez ID:85315; OMIM: 607780; Uniprot ID:MPRB_HUMAN; ENSEMBL ID: ENSG00000170915; HGNC ID: 15708
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus22 / 56401239
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult65 / 193912133
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor20 / 114246175
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor9 / 26384534
glioma7 / 10688365
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma2 / 7175527
non-neoplasia4 / 9725041
normal150 / 336030744
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain86 / 110098978
cervix0 / 481710 
connective tissue2 / 14925513
ear1 / 1621261
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye13 / 21105461
heart1 / 8962611
intestine29 / 234472123
kidney5 / 21177723
larynx0 / 241450 
liver0 / 2077430 
lung8 / 33697423
lymph1 / 4427022
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve3 / 15768190
ovary2 / 10205119
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta4 / 28082514
prostate4 / 18934521
salivary gland0 / 201550 
skin5 / 21057423
spleen0 / 539520 
stomach4 / 9661941
testis16 / 33044248
thymus6 / 8113173
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P214281
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.55 ± 0.49
Basal Forebrain9.08 ± 0.3
Basal Part of Pons8.63 ± 0.28
Cerebellar Cortex8.62 ± 0.19
Cerebellar Nuclei9.69 ± 0.36
Claustrum8.5 ± 0.32
Epithalamus8.74 ± 0.54
Frontal Lobe8.92 ± 0.56
Globus Pallidus10.32 ± 0.32
Hypothalamus8.74 ± 0.25
Insula8.54 ± 0.33
Limbic Lobe8.48 ± 0.52
Mesencephalon9.12 ± 0.52
Myelencephalon9.01 ± 0.52
Occipital Lobe9.28 ± 0.48
Parietal Lobe9.02 ± 0.43
Pontine Tegmentum9.18 ± 0.48
Striatum9.41 ± 0.52
Subthalamus9.32 ± 0.21
Temporal Lobe8.64 ± 0.38
Thalamus9.43 ± 0.31
White Matter10.94 ± 0.27
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Paqr8CBCerebellum17.64
24.91
Paqr8CTXCerebral cortex3.86
3.27
Paqr8HIPHippocampal region5.77
6.34
Paqr8HPFHippocampal formation4.46
4.26
Paqr8HYHypothalamus0.87
0.85
Paqr8LSXLateral septal complex1.21
1.32
Paqr8MBMidbrain2.45
2.78
Paqr8MYMedulla12.19
13.34
Paqr8OLFOlfactory bulb2.72
2.87
Paqr8PPons9.07
9.4
Paqr8PALPallidum0.9
0.87
Paqr8RHPRetrohippocampal region3.28
2.47
Paqr8sAMYStriatum-like amygdalar nuclei0.72
0.74
Paqr8STRStriatum0.85
0.89
Paqr8STRdStriatum dorsal region0.87
0.83
Paqr8STRvStriatum ventral region0.74
1.11
Paqr8THThalamus14.03
14.4
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018