AutismKB 2.0

Annotation Detail for DGCR6L


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Basic Information Top
Gene Symbol:DGCR6L ( FLJ10666 )
Gene Full Name: DiGeorge syndrome critical region gene 6-like
Band: 22q11.21
Quick LinksEntrez ID:85359; OMIM: 609459; Uniprot ID:DGC6L_HUMAN; ENSEMBL ID: ENSG00000128185; HGNC ID: 18551
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst3 / 6231948
fetus26 / 56401246
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult61 / 193912131
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor8 / 11424670
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor2 / 2638457
glioma6 / 10688356
head and neck tumor4 / 13630229
kidney tumor6 / 6895987
leukemia2 / 9584220
liver tumor6 / 9635962
lung tumor2 / 10312719
lymphoma3 / 7175541
non-neoplasia2 / 9725020
normal94 / 336030727
ovarian tumor4 / 7668252
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone4 / 7165555
bone marrow2 / 4880140
brain22 / 110098919
cervix2 / 4817141
connective tissue2 / 14925513
ear1 / 1621261
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye6 / 21105428
heart1 / 8962611
intestine12 / 23447251
kidney15 / 21177770
larynx0 / 241450 
liver6 / 20774328
lung22 / 33697465
lymph2 / 4427045
lymph node1 / 9161010
mammary gland1 / 1532716
mouth0 / 670520 
muscle12 / 107715111
nerve0 / 157680 
ovary5 / 10205148
pancreas6 / 21481227
parathyroid5 / 20539243
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate5 / 18934526
salivary gland3 / 20155148
skin5 / 21057423
spleen1 / 5395218
stomach3 / 9661931
testis6 / 33044218
thymus2 / 8113124
thyroid2 / 4747342
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus5 / 23287821
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208024_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts52.55
Adipocyte115.05
AdrenalCortex31.25
Adrenalgland94.05
Amygdala156.7
Appendix51.35
AtrioventricularNode26.85
BDCA4+_DentriticCells81.25
Bonemarrow67
BronchialEpithelialCells78.95
CD105+_Endothelial78.85
CD14+_Monocytes111.9
CD19+_BCells(neg._sel.)32.6
CD33+_Myeloid65.7
CD34+107.3
CD4+_Tcells166.6
CD56+_NKCells89.05
CD71+_EarlyErythroid29.05
CD8+_Tcells129.8
CardiacMyocytes87.15
Caudatenucleus148.9
Cerebellum59.95
CerebellumPeduncles152.15
CiliaryGanglion14.25
CingulateCortex90.85
Colorectaladenocarcinoma144.05
DorsalRootGanglion36.4
FetalThyroid114.75
Fetalbrain110.15
Fetalliver54.35
Fetallung90.5
GlobusPallidus39.1
Heart462.1
Hypothalamus149
Kidney115.5
Leukemia_chronicMyelogenousK-562148.5
Leukemia_promyelocytic-HL-6044.5
Leukemialymphoblastic(MOLT-4)151.75
Liver911.05
Lung396.95
Lymphnode65.95
Lymphoma_burkitts(Daudi)28.05
Lymphoma_burkitts(Raji)60.3
MedullaOblongata80.3
OccipitalLobe97.65
OlfactoryBulb72.8
Ovary20.05
Pancreas83.7
PancreaticIslet90.55
ParietalLobe78.25
Pituitary159.7
Placenta64.25
Pons97.3
PrefrontalCortex157.65
Prostate211.15
Salivarygland14.9
SkeletalMuscle98.45
Skin36.05
SmoothMuscle78.7
Spinalcord140.05
SubthalamicNucleus44.25
SuperiorCervicalGanglion43
TemporalLobe206.85
Testis458.6
TestisGermCell359.15
TestisIntersitial331.2
TestisLeydigCell231.95
TestisSeminiferousTubule221.8
Thalamus151
Thymus118.7
Thyroid472.7
Tongue118.3
Tonsil37.15
Trachea50.95
TrigeminalGanglion77.75
Uterus108.95
UterusCorpus36.85
WholeBlood84.3
Wholebrain267.4
colon45.8
pineal_day216.62
pineal_night228.28
retina195.625
small_intestine38.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P143569
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.72 ± 0.53
Basal Forebrain8.01 ± 0.27
Basal Part of Pons8.14 ± 0.49
Cerebellar Cortex7.81 ± 0.41
Cerebellar Nuclei7.88 ± 0.32
Claustrum7.42 ± 0.66
Epithalamus8.2 ± 0.34
Frontal Lobe8.09 ± 0.42
Globus Pallidus7.7 ± 0.53
Hypothalamus8.16 ± 0.46
Insula8.1 ± 0.39
Limbic Lobe7.79 ± 0.56
Mesencephalon7.87 ± 0.42
Myelencephalon7.91 ± 0.49
Occipital Lobe7.38 ± 0.48
Parietal Lobe7.87 ± 0.43
Pontine Tegmentum7.87 ± 0.47
Striatum7.74 ± 0.47
Subthalamus8.27 ± 0.32
Temporal Lobe8.13 ± 0.41
Thalamus7.92 ± 0.39
White Matter7.15 ± 0.26
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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