AutismKB 2.0

Annotation Detail for CAMK1


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Basic Information Top
Gene Symbol:CAMK1 ( CAMKI,MGC120317,MGC120318 )
Gene Full Name: calcium/calmodulin-dependent protein kinase I
Band: 3p25.3
Quick LinksEntrez ID:8536; OMIM: 604998; Uniprot ID:KCC1A_HUMAN; ENSEMBL ID: ENSG00000134072; HGNC ID: 1459
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus17 / 56401230
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult79 / 193912140
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma6 / 8282372
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor7 / 26384526
glioma11 / 106883102
head and neck tumor4 / 13630229
kidney tumor3 / 6895943
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal107 / 336030731
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma3 / 4635664
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone5 / 7165569
bone marrow1 / 4880120
brain52 / 110098947
cervix4 / 4817183
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye9 / 21105442
heart1 / 8962611
intestine8 / 23447234
kidney6 / 21177728
larynx0 / 241450 
liver1 / 2077434
lung8 / 33697423
lymph0 / 442700 
lymph node10 / 91610109
mammary gland8 / 15327152
mouth3 / 6705244
muscle3 / 10771527
nerve0 / 157680 
ovary7 / 10205168
pancreas1 / 2148124
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate4 / 18934521
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach2 / 9661920
testis5 / 33044215
thymus0 / 811310 
thyroid1 / 4747321
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204392_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.9
Adipocyte15.95
AdrenalCortex56.05
Adrenalgland31.25
Amygdala56.05
Appendix8.4
AtrioventricularNode6.65
BDCA4+_DentriticCells9.75
Bonemarrow8.25
BronchialEpithelialCells8.35
CD105+_Endothelial8.55
CD14+_Monocytes84.4
CD19+_BCells(neg._sel.)7.35
CD33+_Myeloid39.05
CD34+9.3
CD4+_Tcells9.15
CD56+_NKCells10.35
CD71+_EarlyErythroid4.65
CD8+_Tcells5.9
CardiacMyocytes10.55
Caudatenucleus13.3
Cerebellum6.9
CerebellumPeduncles9.75
CiliaryGanglion5.85
CingulateCortex17.75
Colorectaladenocarcinoma8.65
DorsalRootGanglion6.65
FetalThyroid8.25
Fetalbrain14.95
Fetalliver7.2
Fetallung7.2
GlobusPallidus6.4
Heart10.85
Hypothalamus11.25
Kidney6.8
Leukemia_chronicMyelogenousK-5627.65
Leukemia_promyelocytic-HL-607.45
Leukemialymphoblastic(MOLT-4)6.75
Liver16.25
Lung29.15
Lymphnode7.4
Lymphoma_burkitts(Daudi)10.7
Lymphoma_burkitts(Raji)11.6
MedullaOblongata12.35
OccipitalLobe24.4
OlfactoryBulb6.7
Ovary5.75
Pancreas6.8
PancreaticIslet9.05
ParietalLobe15.9
Pituitary11.35
Placenta7.05
Pons9.85
PrefrontalCortex59
Prostate50.85
Salivarygland6.7
SkeletalMuscle9.3
Skin6.3
SmoothMuscle9.75
Spinalcord9.1
SubthalamicNucleus11.55
SuperiorCervicalGanglion9.4
TemporalLobe29.7
Testis13.75
TestisGermCell12.95
TestisIntersitial7.1
TestisLeydigCell8.35
TestisSeminiferousTubule7.3
Thalamus12.1
Thymus6.8
Thyroid28.6
Tongue7.35
Tonsil8.35
Trachea7.1
TrigeminalGanglion8.15
Uterus7.1
UterusCorpus7.5
WholeBlood24.75
Wholebrain94.45
colon8.6
pineal_day10.1
pineal_night10.34
retina11.625
small_intestine9.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9918_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.38 ± 0.44
Basal Forebrain9.48 ± 0.18
Basal Part of Pons9.25 ± 0.3
Cerebellar Cortex9.24 ± 0.2
Cerebellar Nuclei8.79 ± 0.3
Claustrum10.01 ± 0.39
Epithalamus9.07 ± 0.56
Frontal Lobe9.58 ± 0.45
Globus Pallidus8.86 ± 0.71
Hypothalamus9.35 ± 0.45
Insula9.57 ± 0.34
Limbic Lobe10.25 ± 0.57
Mesencephalon9.57 ± 0.51
Myelencephalon9.69 ± 0.39
Occipital Lobe10.55 ± 0.62
Parietal Lobe9.81 ± 0.47
Pontine Tegmentum9.87 ± 0.47
Striatum10.22 ± 0.44
Subthalamus9.23 ± 0.08
Temporal Lobe9.86 ± 0.4
Thalamus9.59 ± 0.42
White Matter7.97 ± 0.5
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Camk1CBCerebellum17.79
24.48
Camk1CTXCerebral cortex52.38
40.37
Camk1HIPHippocampal region16.36
17.01
Camk1HPFHippocampal formation28.97
27.4
Camk1HYHypothalamus12.82
9.47
Camk1LSXLateral septal complex7.34
4.78
Camk1MBMidbrain16.77
14.7
Camk1MYMedulla18.73
19.96
Camk1OLFOlfactory bulb57.56
51.65
Camk1PPons12.38
12.93
Camk1PALPallidum14.52
12.53
Camk1RHPRetrohippocampal region49.98
41.71
Camk1sAMYStriatum-like amygdalar nuclei25.82
18.18
Camk1STRStriatum11.5
8.87
Camk1STRdStriatum dorsal region10.46
8.69
Camk1STRvStriatum ventral region8
5.29
Camk1THThalamus23.78
18.52
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00005523 30 168 197 MEDPGSVLSTACGTPGYVAPEVLAQKPYSK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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