AutismKB 2.0

Annotation Detail for RHPN2


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Basic Information Top
Gene Symbol:RHPN2 ( P76RBE,RHOBP )
Gene Full Name: rhophilin, Rho GTPase binding protein 2
Band: 19q13.12
Quick LinksEntrez ID:85415; OMIM: NA; Uniprot ID:RHPN2_HUMAN; ENSEMBL ID: ENSG00000131941; HGNC ID: 19974
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst1 / 6231916
fetus7 / 56401212
neonate1 / 3109732
infant0 / 236200 
juvenile2 / 5555635
adult52 / 193912126
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor8 / 26384530
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor2 / 9635920
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal56 / 336030716
ovarian tumor8 / 76682104
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer4 / 10268038
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain24 / 110098921
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye5 / 21105423
heart1 / 8962611
intestine9 / 23447238
kidney4 / 21177718
larynx0 / 241450 
liver2 / 2077439
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary8 / 10205178
pancreas0 / 2148120 
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate9 / 18934547
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach9 / 9661993
testis9 / 33044227
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea18 / 52413343
umbilical cord0 / 136800 
uterus14 / 23287860
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15286_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.18 ± 0.62
Basal Forebrain6.39 ± 0.18
Basal Part of Pons5.53 ± 0.56
Cerebellar Cortex6.69 ± 0.29
Cerebellar Nuclei5.78 ± 0.57
Claustrum5.99 ± 0.59
Epithalamus7.32 ± 0.55
Frontal Lobe6.14 ± 0.59
Globus Pallidus5.96 ± 0.67
Hypothalamus6.15 ± 0.5
Insula6.24 ± 0.47
Limbic Lobe5.78 ± 0.66
Mesencephalon6.43 ± 0.51
Myelencephalon6.26 ± 0.71
Occipital Lobe6.22 ± 0.6
Parietal Lobe6.05 ± 0.59
Pontine Tegmentum6.45 ± 0.61
Striatum7.06 ± 0.96
Subthalamus5.49 ± 0.46
Temporal Lobe6.14 ± 0.45
Thalamus6.71 ± 0.53
White Matter4.62 ± 0.42
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018