AutismKB 2.0

Annotation Detail for UNK


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Basic Information Top
Gene Symbol:UNK ( KIAA1753,ZC3H5,ZC3HDC5 )
Gene Full Name: unkempt homolog (Drosophila)
Band: 17q25.3
Quick LinksEntrez ID:85451; OMIM: NA; Uniprot ID:UNK_HUMAN; ENSEMBL ID: ENSG00000132478; HGNC ID: 29369
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst5 / 6231980
fetus13 / 56401223
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult59 / 193912130
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor14 / 26384553
glioma2 / 10688318
head and neck tumor14 / 136302102
kidney tumor3 / 6895943
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal82 / 336030724
ovarian tumor3 / 7668239
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer1 / 1026809
retinoblastoma3 / 4635664
skin tumor7 / 12494956
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone2 / 7165527
bone marrow0 / 488010 
brain26 / 110098923
cervix0 / 481710 
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye12 / 21105456
heart0 / 896260 
intestine4 / 23447217
kidney5 / 21177723
larynx0 / 241450 
liver2 / 2077439
lung9 / 33697426
lymph0 / 442700 
lymph node5 / 9161054
mammary gland5 / 15327132
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary2 / 10205119
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta8 / 28082528
prostate1 / 1893455
salivary gland0 / 201550 
skin7 / 21057433
spleen4 / 5395274
stomach3 / 9661931
testis8 / 33044224
thymus1 / 8113112
thyroid13 / 47473273
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus11 / 23287847
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_181_PI416573500
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.46 ± 1.06
Basal Forebrain2.14 ± 0.59
Basal Part of Pons1.62 ± 0.31
Cerebellar Cortex2.18 ± 0.51
Cerebellar Nuclei2.28 ± 0.76
Claustrum2.64 ± 0.73
Epithalamus1.7 ± 0.75
Frontal Lobe1.78 ± 0.76
Globus Pallidus2.34 ± 0.75
Hypothalamus1.91 ± 0.67
Insula1.76 ± 0.53
Limbic Lobe1.94 ± 0.67
Mesencephalon2.08 ± 0.68
Myelencephalon2.01 ± 0.7
Occipital Lobe2.08 ± 0.59
Parietal Lobe2.06 ± 0.84
Pontine Tegmentum2.11 ± 0.92
Striatum1.88 ± 0.74
Subthalamus2.11 ± 0.75
Temporal Lobe1.93 ± 0.76
Thalamus1.9 ± 0.63
White Matter2.53 ± 0.47
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00499855 11 361 371 TEQQFHPEIYK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018