AutismKB 2.0

Annotation Detail for TSPYL5


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Basic Information Top
Gene Symbol:TSPYL5 ( KIAA1750 )
Gene Full Name: TSPY-like 5
Band: 8q22.1
Quick LinksEntrez ID:85453; OMIM: NA; Uniprot ID:TSYL5_HUMAN; ENSEMBL ID: ENSG00000180543; HGNC ID: 29367
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus36 / 56401263
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult18 / 19391219
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor3 / 26384511
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal104 / 336030730
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain33 / 110098929
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye7 / 21105433
heart3 / 8962633
intestine0 / 2344720 
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung5 / 33697414
lymph0 / 442700 
lymph node3 / 9161032
mammary gland4 / 15327126
mouth2 / 6705229
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate3 / 18934515
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach0 / 966190 
testis16 / 33044248
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213122_at
Cell line Expression level Expression bar
721_B_lymphoblasts90.5
Adipocyte18.7
AdrenalCortex23.25
Adrenalgland32.65
Amygdala119.85
Appendix42.7
AtrioventricularNode14.9
BDCA4+_DentriticCells29.35
Bonemarrow16.7
BronchialEpithelialCells10.2
CD105+_Endothelial9.65
CD14+_Monocytes11.3
CD19+_BCells(neg._sel.)64.35
CD33+_Myeloid16.75
CD34+68.75
CD4+_Tcells13.55
CD56+_NKCells19.8
CD71+_EarlyErythroid12.5
CD8+_Tcells11.75
CardiacMyocytes29.95
Caudatenucleus65.8
Cerebellum61.05
CerebellumPeduncles22.4
CiliaryGanglion20.75
CingulateCortex43.15
Colorectaladenocarcinoma10.7
DorsalRootGanglion21.7
FetalThyroid20.9
Fetalbrain102.9
Fetalliver32.85
Fetallung25.4
GlobusPallidus41.35
Heart22.5
Hypothalamus168
Kidney34.6
Leukemia_chronicMyelogenousK-56225.25
Leukemia_promyelocytic-HL-6010.5
Leukemialymphoblastic(MOLT-4)7.55
Liver20.8
Lung31.25
Lymphnode13.2
Lymphoma_burkitts(Daudi)16.75
Lymphoma_burkitts(Raji)16.15
MedullaOblongata68.85
OccipitalLobe80.35
OlfactoryBulb37.15
Ovary28.65
Pancreas11.45
PancreaticIslet50
ParietalLobe56.9
Pituitary391.55
Placenta17.35
Pons46.25
PrefrontalCortex179.25
Prostate62.9
Salivarygland15.9
SkeletalMuscle29.25
Skin15.45
SmoothMuscle26.6
Spinalcord45.65
SubthalamicNucleus33.15
SuperiorCervicalGanglion26.95
TemporalLobe53.45
Testis554.8
TestisGermCell534.2
TestisIntersitial313.3
TestisLeydigCell261.05
TestisSeminiferousTubule331.35
Thalamus50.4
Thymus21.8
Thyroid33.1
Tongue17.45
Tonsil15.85
Trachea24.05
TrigeminalGanglion20.5
Uterus58.45
UterusCorpus28.55
WholeBlood12.5
Wholebrain86.2
colon40.65
pineal_day345.56
pineal_night1182.38
retina150.825
small_intestine55.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5052_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.16 ± 0.69
Basal Forebrain3.94 ± 0.49
Basal Part of Pons4.3 ± 0.59
Cerebellar Cortex3.84 ± 0.36
Cerebellar Nuclei3.7 ± 0.4
Claustrum3.69 ± 0.61
Epithalamus3.8 ± 0.66
Frontal Lobe4.08 ± 0.46
Globus Pallidus2.8 ± 0.89
Hypothalamus3.85 ± 0.7
Insula4.02 ± 0.43
Limbic Lobe4.11 ± 0.55
Mesencephalon4.05 ± 0.62
Myelencephalon3.98 ± 0.52
Occipital Lobe3.99 ± 0.65
Parietal Lobe4.13 ± 0.53
Pontine Tegmentum3.98 ± 0.53
Striatum4.03 ± 0.71
Subthalamus3.84 ± 0.35
Temporal Lobe4.26 ± 0.46
Thalamus3.91 ± 0.54
White Matter3.39 ± 0.84
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tspyl5CBCerebellum2.06
2.19
Tspyl5CTXCerebral cortex8.13
5.42
Tspyl5HIPHippocampal region5.51
4.91
Tspyl5HPFHippocampal formation6.37
5.27
Tspyl5HYHypothalamus0.34
0.23
Tspyl5LSXLateral septal complex0.28
0.24
Tspyl5MBMidbrain1.02
1.03
Tspyl5MYMedulla5.99
6.56
Tspyl5OLFOlfactory bulb6.13
4.75
Tspyl5PPons2.55
2.74
Tspyl5PALPallidum0.52
0.4
Tspyl5RHPRetrohippocampal region8.06
5.99
Tspyl5sAMYStriatum-like amygdalar nuclei0.58
0.37
Tspyl5STRStriatum1.44
0.98
Tspyl5STRdStriatum dorsal region1.6
1.14
Tspyl5STRvStriatum ventral region1.73
0.94
Tspyl5THThalamus0.66
0.51
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00073782 10 81 90 LPLDCGLALR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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