AutismKB 2.0

Annotation Detail for DIXDC1


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Basic Information Top
Gene Symbol:DIXDC1 ( CCD1,KIAA1735 )
Gene Full Name: DIX domain containing 1
Band: 11q23.1
Quick LinksEntrez ID:85458; OMIM: 610493; Uniprot ID:DIXC1_HUMAN; ENSEMBL ID: ENSG00000150764; HGNC ID: 23695
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst5 / 6231980
fetus27 / 56401247
neonate1 / 3109732
infant2 / 2362084
juvenile1 / 5555617
adult56 / 193912128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor4 / 26384515
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal142 / 336030742
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone11 / 71655153
bone marrow1 / 4880120
brain79 / 110098971
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue15 / 21572269
esophagus0 / 202090 
eye6 / 21105428
heart1 / 8962611
intestine2 / 2344728
kidney1 / 2117774
larynx0 / 241450 
liver6 / 20774328
lung7 / 33697420
lymph0 / 442700 
lymph node0 / 916100 
mammary gland5 / 15327132
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary2 / 10205119
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta4 / 28082514
prostate2 / 18934510
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach2 / 9661920
testis12 / 33044236
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus11 / 23287847
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214724_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.2
Adipocyte40.6
AdrenalCortex12.45
Adrenalgland10.6
Amygdala195.5
Appendix19.55
AtrioventricularNode10
BDCA4+_DentriticCells9.05
Bonemarrow10.7
BronchialEpithelialCells8.05
CD105+_Endothelial8.95
CD14+_Monocytes8.9
CD19+_BCells(neg._sel.)8.9
CD33+_Myeloid9.9
CD34+11.85
CD4+_Tcells8.6
CD56+_NKCells9.75
CD71+_EarlyErythroid8.4
CD8+_Tcells7.9
CardiacMyocytes12.3
Caudatenucleus20.55
Cerebellum41.15
CerebellumPeduncles37.8
CiliaryGanglion10.55
CingulateCortex20.6
Colorectaladenocarcinoma8.3
DorsalRootGanglion11.05
FetalThyroid9.8
Fetalbrain84
Fetalliver8.35
Fetallung12.2
GlobusPallidus8.95
Heart13.8
Hypothalamus106.8
Kidney9.3
Leukemia_chronicMyelogenousK-5629.1
Leukemia_promyelocytic-HL-607.45
Leukemialymphoblastic(MOLT-4)6.55
Liver19.2
Lung14.6
Lymphnode8.1
Lymphoma_burkitts(Daudi)11.4
Lymphoma_burkitts(Raji)14.6
MedullaOblongata26.45
OccipitalLobe80.5
OlfactoryBulb33.6
Ovary8.4
Pancreas7.75
PancreaticIslet11
ParietalLobe44.8
Pituitary16
Placenta14.65
Pons10.25
PrefrontalCortex71.85
Prostate29.85
Salivarygland8.2
SkeletalMuscle13.55
Skin9.25
SmoothMuscle11.3
Spinalcord66.6
SubthalamicNucleus10.65
SuperiorCervicalGanglion18.65
TemporalLobe10.65
Testis20.45
TestisGermCell16.4
TestisIntersitial13.75
TestisLeydigCell10.75
TestisSeminiferousTubule11.5
Thalamus31.6
Thymus7
Thyroid53.9
Tongue11
Tonsil8.6
Trachea17.6
TrigeminalGanglion12.15
Uterus95.3
UterusCorpus16.15
WholeBlood8.75
Wholebrain50.7
colon35.95
pineal_day12.18
pineal_night19.32
retina159.575
small_intestine16.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12427_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.94 ± 0.4
Basal Forebrain7.18 ± 0.26
Basal Part of Pons6.8 ± 0.49
Cerebellar Cortex7.19 ± 0.23
Cerebellar Nuclei7.25 ± 0.46
Claustrum7.76 ± 0.39
Epithalamus6.9 ± 0.3
Frontal Lobe6.94 ± 0.49
Globus Pallidus7.6 ± 0.31
Hypothalamus6.95 ± 0.31
Insula6.97 ± 0.31
Limbic Lobe6.95 ± 0.6
Mesencephalon7.16 ± 0.43
Myelencephalon7.01 ± 0.5
Occipital Lobe6.95 ± 0.41
Parietal Lobe6.94 ± 0.48
Pontine Tegmentum7.07 ± 0.34
Striatum6.58 ± 0.39
Subthalamus6.91 ± 0.31
Temporal Lobe6.99 ± 0.39
Thalamus7.15 ± 0.41
White Matter8.95 ± 0.51
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dixdc1CBCerebellum14.88
14.08
Dixdc1CTXCerebral cortex12.91
8.96
Dixdc1HIPHippocampal region15.08
15.5
Dixdc1HPFHippocampal formation13.12
12.24
Dixdc1HYHypothalamus1.01
0.72
Dixdc1LSXLateral septal complex1.1
0.77
Dixdc1MBMidbrain3.92
3.28
Dixdc1MYMedulla8.16
8.31
Dixdc1OLFOlfactory bulb5.85
3.95
Dixdc1PPons6.82
6.41
Dixdc1PALPallidum1.89
1.42
Dixdc1RHPRetrohippocampal region9.6
7.4
Dixdc1sAMYStriatum-like amygdalar nuclei1.93
1.52
Dixdc1STRStriatum3.15
2.18
Dixdc1STRdStriatum dorsal region3.81
2.71
Dixdc1STRvStriatum ventral region2.38
1.41
Dixdc1THThalamus13.43
10.45
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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