AutismKB 2.0

Annotation Detail for SSH2


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Basic Information Top
Gene Symbol:SSH2 ( KIAA1725,MGC78588,SSH-2 )
Gene Full Name: slingshot homolog 2 (Drosophila)
Band: 17q11.2
Quick LinksEntrez ID:85464; OMIM: 606779; Uniprot ID:SSH2_HUMAN; ENSEMBL ID: ENSG00000141298; HGNC ID: 30580
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus18 / 56401231
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult66 / 193912134
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor9 / 26384534
glioma4 / 10688337
head and neck tumor7 / 13630251
kidney tumor0 / 689590 
leukemia18 / 95842187
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma6 / 7175583
non-neoplasia2 / 9725020
normal97 / 336030728
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood17 / 123478137
bone0 / 716550 
bone marrow1 / 4880120
brain42 / 110098938
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye5 / 21105423
heart1 / 8962611
intestine8 / 23447234
kidney4 / 21177718
larynx1 / 2414541
liver2 / 2077439
lung10 / 33697429
lymph5 / 44270112
lymph node10 / 91610109
mammary gland0 / 1532710 
mouth2 / 6705229
muscle6 / 10771555
nerve0 / 157680 
ovary0 / 1020510 
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx4 / 4132896
pituitary gland0 / 165850 
placenta4 / 28082514
prostate1 / 1893455
salivary gland0 / 201550 
skin6 / 21057428
spleen2 / 5395237
stomach2 / 9661920
testis8 / 33044224
thymus1 / 8113112
thyroid2 / 4747342
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8148_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.65 ± 0.63
Basal Forebrain4.67 ± 0.41
Basal Part of Pons4.44 ± 0.47
Cerebellar Cortex4.81 ± 0.33
Cerebellar Nuclei4.19 ± 0.58
Claustrum4.07 ± 0.95
Epithalamus4.29 ± 0.64
Frontal Lobe4.6 ± 0.42
Globus Pallidus4.55 ± 0.31
Hypothalamus4.29 ± 0.45
Insula4.71 ± 0.23
Limbic Lobe4.56 ± 0.48
Mesencephalon4.52 ± 0.53
Myelencephalon4.49 ± 0.56
Occipital Lobe4.15 ± 0.53
Parietal Lobe4.49 ± 0.52
Pontine Tegmentum4.5 ± 0.55
Striatum4.09 ± 0.58
Subthalamus4.61 ± 0.24
Temporal Lobe4.66 ± 0.48
Thalamus4.33 ± 0.54
White Matter5.88 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ssh2CBCerebellum89.41
100
Ssh2CTXCerebral cortex100
89.55
Ssh2HIPHippocampal region55.3
84.22
Ssh2HPFHippocampal formation70.81
85.91
Ssh2HYHypothalamus56.5
49.18
Ssh2LSXLateral septal complex60.68
47.2
Ssh2MBMidbrain42.83
41.14
Ssh2MYMedulla50.64
50.04
Ssh2OLFOlfactory bulb93.19
93.32
Ssh2PPons52.28
55.87
Ssh2PALPallidum75.36
71.26
Ssh2RHPRetrohippocampal region99.68
91.07
Ssh2sAMYStriatum-like amygdalar nuclei69.04
52.97
Ssh2STRStriatum100
87.37
Ssh2STRdStriatum dorsal region100
91.77
Ssh2STRvStriatum ventral region100
100
Ssh2THThalamus34.1
29.34
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018