AutismKB 2.0

Annotation Detail for CDC14B


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Basic Information Top
Gene Symbol:CDC14B ( CDC14B3,Cdc14B1,Cdc14B2,hCDC14B )
Gene Full Name: CDC14 cell division cycle 14 homolog B (S. cerevisiae)
Band: 9q22.32-q22.33
Quick LinksEntrez ID:8555; OMIM: 603505; Uniprot ID:CC14B_HUMAN; ENSEMBL ID: ENSG00000081377; HGNC ID: 1719
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst6 / 6231996
fetus30 / 56401253
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult55 / 193912128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor10 / 26384537
glioma2 / 10688318
head and neck tumor6 / 13630244
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor5 / 9635951
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal147 / 336030743
ovarian tumor5 / 7668265
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone3 / 7165541
bone marrow0 / 488010 
brain40 / 110098936
cervix0 / 481710 
connective tissue3 / 14925520
ear3 / 16212185
embryonic tissue12 / 21572255
esophagus0 / 202090 
eye6 / 21105428
heart3 / 8962633
intestine7 / 23447229
kidney12 / 21177756
larynx1 / 2414541
liver7 / 20774333
lung8 / 33697423
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth5 / 6705274
muscle4 / 10771537
nerve1 / 1576863
ovary5 / 10205148
pancreas11 / 21481251
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta2 / 2808257
prostate7 / 18934536
salivary gland0 / 201550 
skin5 / 21057423
spleen2 / 5395237
stomach5 / 9661951
testis23 / 33044269
thymus2 / 8113124
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus12 / 23287851
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208022_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6
Adipocyte9.1
AdrenalCortex5.4
Adrenalgland4.45
Amygdala8.7
Appendix5.3
AtrioventricularNode4.05
BDCA4+_DentriticCells5.4
Bonemarrow5.1
BronchialEpithelialCells5.2
CD105+_Endothelial5.45
CD14+_Monocytes5.35
CD19+_BCells(neg._sel.)5.65
CD33+_Myeloid6.05
CD34+6.65
CD4+_Tcells6.15
CD56+_NKCells5.9
CD71+_EarlyErythroid4.5
CD8+_Tcells5.05
CardiacMyocytes6.85
Caudatenucleus4.7
Cerebellum4.1
CerebellumPeduncles5.8
CiliaryGanglion3.75
CingulateCortex6.1
Colorectaladenocarcinoma5.3
DorsalRootGanglion4.05
FetalThyroid7
Fetalbrain5.2
Fetalliver4.5
Fetallung4.25
GlobusPallidus3.8
Heart6.85
Hypothalamus8.25
Kidney5.9
Leukemia_chronicMyelogenousK-5624.65
Leukemia_promyelocytic-HL-604.6
Leukemialymphoblastic(MOLT-4)4
Liver10.45
Lung6.15
Lymphnode4.5
Lymphoma_burkitts(Daudi)6.7
Lymphoma_burkitts(Raji)7.1
MedullaOblongata6
OccipitalLobe5.75
OlfactoryBulb7.65
Ovary3.5
Pancreas4.3
PancreaticIslet5.65
ParietalLobe5.6
Pituitary6.05
Placenta5.45
Pons4.85
PrefrontalCortex18.65
Prostate17.75
Salivarygland3.95
SkeletalMuscle6.5
Skin4
SmoothMuscle5.7
Spinalcord5.3
SubthalamicNucleus4.8
SuperiorCervicalGanglion5.95
TemporalLobe4.8
Testis9.85
TestisGermCell12.85
TestisIntersitial6.25
TestisLeydigCell5.2
TestisSeminiferousTubule5.7
Thalamus5.25
Thymus4.1
Thyroid17.7
Tongue5.2
Tonsil4.95
Trachea8.6
TrigeminalGanglion5.4
Uterus5.3
UterusCorpus4.65
WholeBlood5.6
Wholebrain8.25
colon11.45
pineal_day20.34
pineal_night57.06
retina16.925
small_intestine13.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P20622
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.98 ± 0.21
Basal Forebrain9.46 ± 0.42
Basal Part of Pons8.43 ± 0.27
Cerebellar Cortex8.46 ± 0.23
Cerebellar Nuclei9.08 ± 0.28
Claustrum9.52 ± 0.33
Epithalamus8.91 ± 0.24
Frontal Lobe8.8 ± 0.36
Globus Pallidus9.75 ± 0.21
Hypothalamus8.87 ± 0.36
Insula8.77 ± 0.21
Limbic Lobe8.88 ± 0.51
Mesencephalon9.11 ± 0.35
Myelencephalon9.01 ± 0.48
Occipital Lobe9.37 ± 0.59
Parietal Lobe8.85 ± 0.36
Pontine Tegmentum9.05 ± 0.38
Striatum9.47 ± 0.29
Subthalamus8.79 ± 0.24
Temporal Lobe8.82 ± 0.31
Thalamus9.13 ± 0.26
White Matter10.5 ± 0.32
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cdc14bCBCerebellum0.33
0.44
Cdc14bCTXCerebral cortex0.87
0.72
Cdc14bHIPHippocampal region0.45
0.5
Cdc14bHPFHippocampal formation0.58
0.61
Cdc14bHYHypothalamus0.19
0.24
Cdc14bLSXLateral septal complex0.02
0
Cdc14bMBMidbrain0.29
0.51
Cdc14bMYMedulla6.25
8.82
Cdc14bOLFOlfactory bulb0.64
0.45
Cdc14bPPons0.23
0.18
Cdc14bPALPallidum0.44
0.24
Cdc14bRHPRetrohippocampal region0.85
0.76
Cdc14bsAMYStriatum-like amygdalar nuclei2.3
1.74
Cdc14bSTRStriatum1.54
1.16
Cdc14bSTRdStriatum dorsal region2.26
1.71
Cdc14bSTRvStriatum ventral region0.16
0.18
Cdc14bTHThalamus0.68
0.55
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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