AutismKB 2.0

Annotation Detail for GTPBP10


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Basic Information Top
Gene Symbol:GTPBP10 ( DKFZp686A10121,FLJ38242,MGC104191,ObgH2 )
Gene Full Name: GTP-binding protein 10 (putative)
Band: 7q21.13
Quick LinksEntrez ID:85865; OMIM: 610920; Uniprot ID:GTPBA_HUMAN; ENSEMBL ID: ENSG00000105793; HGNC ID: 25106
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst1 / 6231916
fetus9 / 56401215
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult37 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor6 / 26384522
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor1 / 1031279
lymphoma3 / 7175541
non-neoplasia0 / 972500 
normal75 / 336030722
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor11 / 12494988
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain22 / 110098919
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye8 / 21105437
heart0 / 896260 
intestine8 / 23447234
kidney5 / 21177723
larynx0 / 241450 
liver5 / 20774324
lung10 / 33697429
lymph1 / 4427022
lymph node6 / 9161065
mammary gland4 / 15327126
mouth0 / 670520 
muscle3 / 10771527
nerve0 / 157680 
ovary1 / 1020519
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta3 / 28082510
prostate1 / 1893455
salivary gland0 / 201550 
skin16 / 21057475
spleen0 / 539520 
stomach3 / 9661931
testis8 / 33044224
thymus5 / 8113161
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus3 / 23287812
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6365_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.57 ± 0.38
Basal Forebrain5.62 ± 0.3
Basal Part of Pons5.78 ± 0.31
Cerebellar Cortex6.03 ± 0.17
Cerebellar Nuclei5.67 ± 0.46
Claustrum5.34 ± 0.46
Epithalamus5.66 ± 0.29
Frontal Lobe5.73 ± 0.46
Globus Pallidus5.48 ± 0.29
Hypothalamus5.21 ± 1.13
Insula5.62 ± 0.36
Limbic Lobe5.63 ± 0.4
Mesencephalon5.75 ± 0.36
Myelencephalon5.6 ± 0.45
Occipital Lobe5.69 ± 0.45
Parietal Lobe5.73 ± 0.42
Pontine Tegmentum5.68 ± 0.5
Striatum5.3 ± 0.33
Subthalamus6.13 ± 0.08
Temporal Lobe5.67 ± 0.34
Thalamus5.67 ± 0.42
White Matter6.38 ± 0.12
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gtpbp10CBCerebellum5.87
6.12
Gtpbp10CTXCerebral cortex0.55
0.64
Gtpbp10HIPHippocampal region3.1
2.89
Gtpbp10HPFHippocampal formation2.14
1.87
Gtpbp10HYHypothalamus0.41
1.12
Gtpbp10LSXLateral septal complex0.13
0.1
Gtpbp10MBMidbrain0.98
1.24
Gtpbp10MYMedulla0.98
1.19
Gtpbp10OLFOlfactory bulb0.8
0.76
Gtpbp10PPons0.65
1
Gtpbp10PALPallidum0.13
0.27
Gtpbp10RHPRetrohippocampal region0.2
0.18
Gtpbp10sAMYStriatum-like amygdalar nuclei0.27
0.44
Gtpbp10STRStriatum0.45
0.54
Gtpbp10STRdStriatum dorsal region0.48
0.66
Gtpbp10STRvStriatum ventral region0.5
0.39
Gtpbp10THThalamus0.89
1.05
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00028245 26 315 340 TVEFQHIIPISAVTGEGIEELKNCIR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018