AutismKB 2.0

Annotation Detail for KLF7


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Basic Information Top
Gene Symbol:KLF7 ( UKLF )
Gene Full Name: Kruppel-like factor 7 (ubiquitous)
Band: 2q33.3
Quick LinksEntrez ID:8609; OMIM: 604865; Uniprot ID:KLF7_HUMAN; ENSEMBL ID: ENSG00000118263; HGNC ID: 6350
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus79 / 564012140
neonate0 / 310970 
infant3 / 23620127
juvenile0 / 555560 
adult74 / 193912138
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor2 / 3436658
chondrosarcoma6 / 8282372
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor19 / 26384572
glioma4 / 10688337
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia5 / 9584252
liver tumor1 / 9635910
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal189 / 336030756
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood7 / 12347856
bone2 / 7165527
bone marrow2 / 4880140
brain107 / 110098997
cervix2 / 4817141
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye7 / 21105433
heart0 / 896260 
intestine4 / 23447217
kidney7 / 21177733
larynx1 / 2414541
liver5 / 20774324
lung14 / 33697441
lymph0 / 442700 
lymph node0 / 916100 
mammary gland6 / 15327139
mouth2 / 6705229
muscle5 / 10771546
nerve1 / 1576863
ovary1 / 1020519
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate4 / 18934521
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach0 / 966190 
testis19 / 33044257
thymus4 / 8113149
thyroid0 / 474730 
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord2 / 13680146
uterus8 / 23287834
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204334_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.65
Adipocyte13.85
AdrenalCortex10.55
Adrenalgland8.75
Amygdala11.1
Appendix18.15
AtrioventricularNode9.4
BDCA4+_DentriticCells11.8
Bonemarrow11.65
BronchialEpithelialCells102.5
CD105+_Endothelial7.95
CD14+_Monocytes12.05
CD19+_BCells(neg._sel.)31.4
CD33+_Myeloid113.95
CD34+11.35
CD4+_Tcells19.5
CD56+_NKCells13.7
CD71+_EarlyErythroid9.6
CD8+_Tcells14.05
CardiacMyocytes26.4
Caudatenucleus9.3
Cerebellum13.05
CerebellumPeduncles37.9
CiliaryGanglion12.15
CingulateCortex19.15
Colorectaladenocarcinoma9.35
DorsalRootGanglion7.85
FetalThyroid12.95
Fetalbrain30.45
Fetalliver9.6
Fetallung7.2
GlobusPallidus7.55
Heart12.9
Hypothalamus11.8
Kidney8.35
Leukemia_chronicMyelogenousK-5629.2
Leukemia_promyelocytic-HL-607.3
Leukemialymphoblastic(MOLT-4)8.45
Liver13.6
Lung11.2
Lymphnode8.3
Lymphoma_burkitts(Daudi)12.55
Lymphoma_burkitts(Raji)11.65
MedullaOblongata17.5
OccipitalLobe13.05
OlfactoryBulb15.2
Ovary7.05
Pancreas9.85
PancreaticIslet13.45
ParietalLobe14.7
Pituitary13.7
Placenta11.7
Pons14.05
PrefrontalCortex22.65
Prostate9.55
Salivarygland9.25
SkeletalMuscle28.55
Skin7.6
SmoothMuscle25.2
Spinalcord11.4
SubthalamicNucleus9.35
SuperiorCervicalGanglion26.8
TemporalLobe11.65
Testis8.95
TestisGermCell8.75
TestisIntersitial8.7
TestisLeydigCell10.4
TestisSeminiferousTubule9.1
Thalamus10.35
Thymus8.35
Thyroid9.3
Tongue16.55
Tonsil9.9
Trachea8.75
TrigeminalGanglion17.4
Uterus13.9
UterusCorpus18.3
WholeBlood10.55
Wholebrain9
colon10.45
pineal_day9.04
pineal_night7.96
retina15.325
small_intestine9.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14740_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.89 ± 0.49
Basal Forebrain4.9 ± 0.31
Basal Part of Pons5.43 ± 0.33
Cerebellar Cortex5.38 ± 0.21
Cerebellar Nuclei4.9 ± 0.46
Claustrum5.45 ± 0.42
Epithalamus4.99 ± 0.59
Frontal Lobe4.92 ± 0.47
Globus Pallidus4.87 ± 0.49
Hypothalamus4.89 ± 0.39
Insula4.9 ± 0.5
Limbic Lobe4.96 ± 0.45
Mesencephalon4.83 ± 0.47
Myelencephalon4.95 ± 0.52
Occipital Lobe5.06 ± 0.45
Parietal Lobe4.8 ± 0.49
Pontine Tegmentum4.87 ± 0.43
Striatum4.52 ± 0.4
Subthalamus4.87 ± 0.48
Temporal Lobe4.93 ± 0.4
Thalamus5.05 ± 0.53
White Matter5.86 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Klf7CBCerebellum100
100
Klf7CTXCerebral cortex100
100
Klf7HIPHippocampal region100
100
Klf7HPFHippocampal formation100
100
Klf7HYHypothalamus100
100
Klf7LSXLateral septal complex100
100
Klf7MBMidbrain100
100
Klf7MYMedulla100
100
Klf7OLFOlfactory bulb100
100
Klf7PPons100
100
Klf7PALPallidum100
100
Klf7RHPRetrohippocampal region100
100
Klf7sAMYStriatum-like amygdalar nuclei100
100
Klf7STRStriatum100
100
Klf7STRdStriatum dorsal region100
100
Klf7STRvStriatum ventral region100
100
Klf7THThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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