AutismKB 2.0

Annotation Detail for ASMTL


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Basic Information Top
Gene Symbol:ASMTL ( ASMTLX,ASMTLY,ASTML )
Gene Full Name: acetylserotonin O-methyltransferase-like
Band: Xp22.3 and Yp11.3
Quick LinksEntrez ID:8623; OMIM: 300162,400011; Uniprot ID:ASML_HUMAN; ENSEMBL ID: ENSG00000169093; HGNC ID: 751
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst5 / 6231980
fetus16 / 56401228
neonate4 / 31097128
infant2 / 2362084
juvenile6 / 55556107
adult119 / 193912161
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma9 / 82823108
colorectal tumor3 / 11424626
esophageal tumor1 / 1729057
gastrointestinal tumor16 / 119369134
germ cell tumor25 / 26384594
glioma9 / 10688384
head and neck tumor4 / 13630229
kidney tumor8 / 68959116
leukemia15 / 95842156
liver tumor5 / 9635951
lung tumor4 / 10312738
lymphoma5 / 7175569
non-neoplasia9 / 9725092
normal223 / 336030766
ovarian tumor11 / 76682143
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS18 / 125680143
prostate cancer4 / 10268038
retinoblastoma2 / 4635643
skin tumor2 / 12494916
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland6 / 33197180
ascites13 / 40015324
bladder2 / 2975767
blood16 / 123478129
bone5 / 7165569
bone marrow10 / 48801204
brain86 / 110098978
cervix1 / 4817120
connective tissue14 / 14925593
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus1 / 2020949
eye15 / 21105471
heart11 / 89626122
intestine13 / 23447255
kidney21 / 21177799
larynx1 / 2414541
liver9 / 20774343
lung18 / 33697453
lymph0 / 442700 
lymph node1 / 9161010
mammary gland8 / 15327152
mouth3 / 6705244
muscle9 / 10771583
nerve0 / 157680 
ovary17 / 102051166
pancreas14 / 21481265
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta10 / 28082535
prostate15 / 18934579
salivary gland1 / 2015549
skin6 / 21057428
spleen7 / 53952129
stomach3 / 9661931
testis15 / 33044245
thymus17 / 81131209
thyroid3 / 4747363
tonsil6 / 16999352
trachea3 / 5241357
umbilical cord1 / 1368073
uterus18 / 23287877
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 36554_at
Cell line Expression level Expression bar
721_B_lymphoblasts116.75
Adipocyte16.6
AdrenalCortex30.3
Adrenalgland19.85
Amygdala54.4
Appendix25.1
AtrioventricularNode19.35
BDCA4+_DentriticCells130.3
Bonemarrow31.75
BronchialEpithelialCells22.1
CD105+_Endothelial29.4
CD14+_Monocytes29.35
CD19+_BCells(neg._sel.)53
CD33+_Myeloid44.75
CD34+68.05
CD4+_Tcells39.15
CD56+_NKCells145.85
CD71+_EarlyErythroid45.2
CD8+_Tcells43.3
CardiacMyocytes33.45
Caudatenucleus18.7
Cerebellum20
CerebellumPeduncles26.55
CiliaryGanglion18.7
CingulateCortex25.45
Colorectaladenocarcinoma28
DorsalRootGanglion18.95
FetalThyroid27.45
Fetalbrain21.1
Fetalliver29
Fetallung23.85
GlobusPallidus17.6
Heart101.65
Hypothalamus30.95
Kidney20.65
Leukemia_chronicMyelogenousK-56219.5
Leukemia_promyelocytic-HL-60149
Leukemialymphoblastic(MOLT-4)26.25
Liver282
Lung123.2
Lymphnode23.95
Lymphoma_burkitts(Daudi)25.9
Lymphoma_burkitts(Raji)234.4
MedullaOblongata21.2
OccipitalLobe18.1
OlfactoryBulb18.55
Ovary16.15
Pancreas16.1
PancreaticIslet19.4
ParietalLobe25.05
Pituitary33.5
Placenta25
Pons21.15
PrefrontalCortex34
Prostate137.85
Salivarygland19.2
SkeletalMuscle38.55
Skin19.15
SmoothMuscle26.15
Spinalcord29.1
SubthalamicNucleus22.4
SuperiorCervicalGanglion35.55
TemporalLobe31.65
Testis16.5
TestisGermCell17.2
TestisIntersitial16.45
TestisLeydigCell20.95
TestisSeminiferousTubule18.75
Thalamus22.3
Thymus39.5
Thyroid265.7
Tongue21.45
Tonsil22.1
Trachea18.1
TrigeminalGanglion33.5
Uterus27.75
UterusCorpus27.25
WholeBlood58.9
Wholebrain63.95
colon20.2
pineal_day71.88
pineal_night73.84
retina84.05
small_intestine18.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P159544
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.52 ± 0.55
Basal Forebrain4.59 ± 0.46
Basal Part of Pons5.19 ± 0.55
Cerebellar Cortex5.2 ± 0.49
Cerebellar Nuclei4.38 ± 0.33
Claustrum4 ± 0.78
Epithalamus5.04 ± 0.6
Frontal Lobe4.97 ± 0.53
Globus Pallidus4.54 ± 0.24
Hypothalamus4.83 ± 0.61
Insula5 ± 0.44
Limbic Lobe4.55 ± 0.67
Mesencephalon4.72 ± 0.49
Myelencephalon4.72 ± 0.65
Occipital Lobe4.31 ± 0.56
Parietal Lobe4.65 ± 0.63
Pontine Tegmentum4.65 ± 0.59
Striatum4.22 ± 0.48
Subthalamus5.24 ± 0.61
Temporal Lobe4.86 ± 0.54
Thalamus4.9 ± 0.5
White Matter5.07 ± 0.62
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ASML_HUMAN_172 34 172 205 AGGYGIQALGGMLVESVHGDFLNVVGFPLNHFCK PRIDE
ASML_HUMAN_251 25 251 275 DAGSRDEKAEAGEAGQATAEAECHR PRIDE
ASML_HUMAN_287 12 287 298 LLELIEGFMLSK PRIDE
ASML_HUMAN_541 23 541 563 VAESCKPGAGLLLVETLLDEEKR PRIDE
PAp00000276 17 260 276 AEAGEAGQATAEAECHR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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