AutismKB 2.0

Annotation Detail for TP63


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TP63 ( AIS,B(p51A),B(p51B),EEC3,KET,LMS,NBP,OFC8,RHS,SHFM4,TP53CP,TP53L,TP73L,p40,p51,p53CP,p63,p73H,p73L )
Gene Full Name: tumor protein p63
Band: 3q28
Quick LinksEntrez ID:8626; OMIM: 603273; Uniprot ID:P63_HUMAN; ENSEMBL ID: ENSG00000073282; HGNC ID: 15979
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus23 / 56401240
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult76 / 193912139
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor2 / 17290115
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor61 / 136302447
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia3 / 9725030
normal55 / 336030716
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor7 / 12494956
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder4 / 29757134
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus2 / 2020998
eye3 / 21105414
heart12 / 89626133
intestine1 / 2344724
kidney0 / 2117770 
larynx2 / 2414582
liver0 / 2077430 
lung8 / 33697423
lymph1 / 4427022
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth54 / 67052805
muscle4 / 10771537
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx5 / 41328120
pituitary gland0 / 165850 
placenta3 / 28082510
prostate8 / 18934542
salivary gland0 / 201550 
skin14 / 21057466
spleen0 / 539520 
stomach0 / 966190 
testis5 / 33044215
thymus6 / 8113173
thyroid1 / 4747321
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211194_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6
Adipocyte4.8
AdrenalCortex5.45
Adrenalgland4.25
Amygdala5.1
Appendix5.3
AtrioventricularNode4.6
BDCA4+_DentriticCells5.15
Bonemarrow5.05
BronchialEpithelialCells76.95
CD105+_Endothelial4.95
CD14+_Monocytes5.25
CD19+_BCells(neg._sel.)5.2
CD33+_Myeloid6.25
CD34+6.1
CD4+_Tcells5.35
CD56+_NKCells5.85
CD71+_EarlyErythroid4.65
CD8+_Tcells4.6
CardiacMyocytes6.85
Caudatenucleus4.4
Cerebellum3.95
CerebellumPeduncles5.75
CiliaryGanglion3.6
CingulateCortex5.05
Colorectaladenocarcinoma4.9
DorsalRootGanglion4.1
FetalThyroid4.8
Fetalbrain4.8
Fetalliver4.35
Fetallung4
GlobusPallidus3.8
Heart6.75
Hypothalamus5.3
Kidney4.15
Leukemia_chronicMyelogenousK-5624.4
Leukemia_promyelocytic-HL-604.35
Leukemialymphoblastic(MOLT-4)3.85
Liver6.75
Lung5.3
Lymphnode4.15
Lymphoma_burkitts(Daudi)6.4
Lymphoma_burkitts(Raji)7.15
MedullaOblongata4.45
OccipitalLobe4.4
OlfactoryBulb3.85
Ovary3.4
Pancreas4.05
PancreaticIslet5.2
ParietalLobe5.4
Pituitary5.75
Placenta5.05
Pons4.75
PrefrontalCortex6.05
Prostate5.65
Salivarygland4
SkeletalMuscle6.3
Skin4.6
SmoothMuscle5.5
Spinalcord5.2
SubthalamicNucleus4.55
SuperiorCervicalGanglion8.35
TemporalLobe4.5
Testis4.2
TestisGermCell3.95
TestisIntersitial4.1
TestisLeydigCell4.9
TestisSeminiferousTubule4.2
Thalamus5.05
Thymus3.85
Thyroid6
Tongue5.05
Tonsil4.85
Trachea4.1
TrigeminalGanglion5.45
Uterus3.9
UterusCorpus4.6
WholeBlood5.35
Wholebrain4.05
colon4.95
pineal_day6.02
pineal_night5.98
retina5.925
small_intestine4.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P273756
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.4 ± 1.16
Basal Forebrain2.8 ± 0.41
Basal Part of Pons2.54 ± 0.71
Cerebellar Cortex2.54 ± 0.98
Cerebellar Nuclei2.92 ± 0.72
Claustrum3.8 ± 1.01
Epithalamus3.21 ± 1.02
Frontal Lobe2.75 ± 0.97
Globus Pallidus3.56 ± 0.9
Hypothalamus2.72 ± 0.79
Insula2.24 ± 0.35
Limbic Lobe2.8 ± 0.89
Mesencephalon2.94 ± 0.87
Myelencephalon2.85 ± 0.85
Occipital Lobe2.64 ± 0.79
Parietal Lobe2.85 ± 0.96
Pontine Tegmentum2.69 ± 0.78
Striatum2.9 ± 0.75
Subthalamus2.82 ± 0.92
Temporal Lobe2.7 ± 0.93
Thalamus2.7 ± 0.72
White Matter2.9 ± 0.23
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00131832 33 556 588 LGCSSCLDYFTTQGLTTIYQIEHYSMDDLASLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved