AutismKB 2.0

Annotation Detail for DNAH17


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Basic Information Top
Gene Symbol:DNAH17 ( DNAHL1,DNEL2,FLJ40457,MGC132767,MGC138489 )
Gene Full Name: dynein, axonemal, heavy chain 17
Band: 17q25.3
Quick LinksEntrez ID:8632; OMIM: 610063; Uniprot ID:; ENSEMBL ID: ENSG00000187775; HGNC ID: 2946
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult10 / 19391215
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor4 / 26384515
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal47 / 336030713
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone0 / 716550 
bone marrow0 / 488010 
brain8 / 11009897
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye5 / 21105423
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx1 / 2414541
liver0 / 2077430 
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach1 / 9661910
testis20 / 33044260
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214229_at
Cell line Expression level Expression bar
721_B_lymphoblasts21.9
Adipocyte4.55
AdrenalCortex4.7
Adrenalgland3.85
Amygdala4.95
Appendix4.8
AtrioventricularNode3.5
BDCA4+_DentriticCells5.05
Bonemarrow4.7
BronchialEpithelialCells4.6
CD105+_Endothelial4.65
CD14+_Monocytes4.8
CD19+_BCells(neg._sel.)4.75
CD33+_Myeloid5.95
CD34+5.65
CD4+_Tcells4.85
CD56+_NKCells5.5
CD71+_EarlyErythroid4.45
CD8+_Tcells4.25
CardiacMyocytes6.05
Caudatenucleus8.55
Cerebellum3.75
CerebellumPeduncles6.1
CiliaryGanglion3.2
CingulateCortex4.75
Colorectaladenocarcinoma4.7
DorsalRootGanglion3.45
FetalThyroid5.25
Fetalbrain4.65
Fetalliver3.95
Fetallung3.65
GlobusPallidus3.65
Heart6.2
Hypothalamus16.1
Kidney3.6
Leukemia_chronicMyelogenousK-5624.25
Leukemia_promyelocytic-HL-604.05
Leukemialymphoblastic(MOLT-4)5.85
Liver6.4
Lung5.05
Lymphnode3.95
Lymphoma_burkitts(Daudi)5.9
Lymphoma_burkitts(Raji)6.7
MedullaOblongata4.25
OccipitalLobe4.7
OlfactoryBulb3.85
Ovary3.2
Pancreas3.8
PancreaticIslet5
ParietalLobe14.9
Pituitary5.4
Placenta4.65
Pons4.4
PrefrontalCortex6.4
Prostate5.5
Salivarygland3.7
SkeletalMuscle7.15
Skin3.45
SmoothMuscle5.2
Spinalcord62.05
SubthalamicNucleus4.2
SuperiorCervicalGanglion5.15
TemporalLobe4.2
Testis77.05
TestisGermCell32.4
TestisIntersitial57.6
TestisLeydigCell19.55
TestisSeminiferousTubule18.1
Thalamus11.7
Thymus3.6
Thyroid5.85
Tongue5.15
Tonsil4.55
Trachea3.85
TrigeminalGanglion5
Uterus3.85
UterusCorpus4.4
WholeBlood5.05
Wholebrain9.65
colon4.7
pineal_day5.68
pineal_night5.6
retina12.975
small_intestine4.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P195272
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.4 ± 0.92
Basal Forebrain3.37 ± 0.66
Basal Part of Pons2.98 ± 0.5
Cerebellar Cortex2.9 ± 0.78
Cerebellar Nuclei3.53 ± 0.74
Claustrum3.52 ± 1.01
Epithalamus3 ± 0.65
Frontal Lobe3.06 ± 0.79
Globus Pallidus3.34 ± 0.76
Hypothalamus2.84 ± 0.4
Insula3.07 ± 1.02
Limbic Lobe3.23 ± 0.79
Mesencephalon3.26 ± 0.8
Myelencephalon3.31 ± 0.78
Occipital Lobe3.36 ± 0.78
Parietal Lobe3.16 ± 0.79
Pontine Tegmentum3.18 ± 0.82
Striatum3.74 ± 0.68
Subthalamus3 ± 0.64
Temporal Lobe3.08 ± 0.81
Thalamus3.44 ± 0.63
White Matter2.49 ± 0.44
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018