AutismKB 2.0

Annotation Detail for AOC3


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Basic Information Top
Gene Symbol:AOC3 ( HPAO,SSAO,VAP-1,VAP1 )
Gene Full Name: amine oxidase, copper containing 3 (vascular adhesion protein 1)
Band: 17q21.31
Quick LinksEntrez ID:8639; OMIM: 603735; Uniprot ID:AOC3_HUMAN; ENSEMBL ID: ENSG00000131471; HGNC ID: 550
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus8 / 56401214
neonate1 / 3109732
infant0 / 236200 
juvenile2 / 5555635
adult70 / 193912136
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor3 / 9635931
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia8 / 9725082
normal129 / 336030738
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain16 / 110098914
cervix0 / 481710 
connective tissue10 / 14925566
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus1 / 2020949
eye5 / 21105423
heart2 / 8962622
intestine10 / 23447242
kidney2 / 2117779
larynx0 / 241450 
liver4 / 20774319
lung16 / 33697447
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth4 / 6705259
muscle2 / 10771518
nerve1 / 1576863
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta30 / 280825106
prostate11 / 18934558
salivary gland0 / 201550 
skin0 / 2105740 
spleen6 / 53952111
stomach12 / 96619124
testis22 / 33044266
thymus12 / 81131147
thyroid1 / 4747321
tonsil0 / 169990 
trachea13 / 52413248
umbilical cord1 / 1368073
uterus184 / 232878790
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204894_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.9
Adipocyte1758.45
AdrenalCortex41.15
Adrenalgland103.15
Amygdala8.8
Appendix108.35
AtrioventricularNode18.7
BDCA4+_DentriticCells7.55
Bonemarrow10.9
BronchialEpithelialCells9.3
CD105+_Endothelial10
CD14+_Monocytes10.75
CD19+_BCells(neg._sel.)9.85
CD33+_Myeloid11.6
CD34+11.5
CD4+_Tcells10.2
CD56+_NKCells10.9
CD71+_EarlyErythroid9.9
CD8+_Tcells8.45
CardiacMyocytes17.45
Caudatenucleus9
Cerebellum8.2
CerebellumPeduncles15.1
CiliaryGanglion44.5
CingulateCortex14.65
Colorectaladenocarcinoma9.55
DorsalRootGanglion13.95
FetalThyroid21.65
Fetalbrain9.9
Fetalliver9
Fetallung290.65
GlobusPallidus9.4
Heart119.1
Hypothalamus9.75
Kidney12.65
Leukemia_chronicMyelogenousK-5628.8
Leukemia_promyelocytic-HL-608.65
Leukemialymphoblastic(MOLT-4)7.5
Liver24.55
Lung1065.45
Lymphnode40.4
Lymphoma_burkitts(Daudi)13.45
Lymphoma_burkitts(Raji)15.3
MedullaOblongata8.5
OccipitalLobe8.9
OlfactoryBulb7.95
Ovary14.5
Pancreas9.4
PancreaticIslet16.9
ParietalLobe12.05
Pituitary11.8
Placenta14.3
Pons13.95
PrefrontalCortex10.75
Prostate161.55
Salivarygland8.95
SkeletalMuscle16.05
Skin14.65
SmoothMuscle11.25
Spinalcord10.45
SubthalamicNucleus11.9
SuperiorCervicalGanglion19.8
TemporalLobe10.35
Testis9.95
TestisGermCell68.8
TestisIntersitial10.7
TestisLeydigCell14.1
TestisSeminiferousTubule8.65
Thalamus10.65
Thymus25.6
Thyroid28.4
Tongue15.35
Tonsil10.55
Trachea30.55
TrigeminalGanglion12.85
Uterus387.25
UterusCorpus10.35
WholeBlood10.35
Wholebrain7.6
colon431.5
pineal_day10.58
pineal_night10.68
retina565.75
small_intestine302.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10541_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.69 ± 0.63
Basal Forebrain4.1 ± 0.5
Basal Part of Pons4.69 ± 0.3
Cerebellar Cortex4.09 ± 0.43
Cerebellar Nuclei4.15 ± 0.5
Claustrum4.9 ± 0.64
Epithalamus3.96 ± 0.64
Frontal Lobe4.36 ± 0.67
Globus Pallidus4.34 ± 0.91
Hypothalamus4.27 ± 0.69
Insula4.1 ± 0.71
Limbic Lobe4.52 ± 0.66
Mesencephalon4.42 ± 0.58
Myelencephalon4.3 ± 0.64
Occipital Lobe4.35 ± 0.75
Parietal Lobe4.39 ± 0.5
Pontine Tegmentum4.2 ± 0.57
Striatum4.5 ± 0.63
Subthalamus4.58 ± 0.19
Temporal Lobe4.33 ± 0.66
Thalamus4.3 ± 0.51
White Matter3.76 ± 0.52
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Aoc3CBCerebellum1.09
1.81
Aoc3CTXCerebral cortex1.43
1.06
Aoc3HIPHippocampal region1.4
1.07
Aoc3HPFHippocampal formation1.66
1.26
Aoc3HYHypothalamus0.1
0.08
Aoc3LSXLateral septal complex0.1
0.56
Aoc3MBMidbrain0.28
0.34
Aoc3MYMedulla0.94
1.05
Aoc3OLFOlfactory bulb2.37
2.49
Aoc3PPons0.27
0.34
Aoc3PALPallidum0.36
0.22
Aoc3RHPRetrohippocampal region2.13
1.51
Aoc3sAMYStriatum-like amygdalar nuclei0.15
0.12
Aoc3STRStriatum0.19
0.19
Aoc3STRdStriatum dorsal region0.17
0.14
Aoc3STRvStriatum ventral region0.36
0.34
Aoc3THThalamus0.78
0.79
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
AOC3_HUMAN_123 10 123 132 EALAIVFFGR PRIDE
AOC3_HUMAN_207 10 207 216 NLVTMTTAPR PRIDE
AOC3_HUMAN_259 5 259 263 WTIQK PRIDE
AOC3_HUMAN_427 16 427 442 DAFCVFEQNQGLPLRR PRIDE
AOC3_HUMAN_507 21 507 527 YGNQVSEHTLGTVHTHSAHFK PRIDE
PAp00026006 19 605 623 IQMLSFAGEPLPQNSSMAR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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