AutismKB 2.0

Annotation Detail for RUNX3


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Basic Information Top
Gene Symbol:RUNX3 ( AML2,CBFA3,FLJ34510,MGC16070,PEBP2aC )
Gene Full Name: runt-related transcription factor 3
Band: 1p36.11
Quick LinksEntrez ID:864; OMIM: 600210; Uniprot ID:RUNX3_HUMAN; ENSEMBL ID: ENSG00000020633; HGNC ID: 10473
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus32 / 56401256
neonate0 / 310970 
infant0 / 236200 
juvenile4 / 5555671
adult46 / 193912123
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor6 / 26384522
glioma1 / 1068839
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia25 / 95842260
liver tumor0 / 963590 
lung tumor4 / 10312738
lymphoma8 / 71755111
non-neoplasia1 / 9725010
normal105 / 336030731
ovarian tumor0 / 766820 
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor9 / 12494972
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood21 / 123478170
bone4 / 7165555
bone marrow1 / 4880120
brain4 / 11009893
cervix2 / 4817141
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye3 / 21105414
heart7 / 8962678
intestine7 / 23447229
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung10 / 33697429
lymph4 / 4427090
lymph node18 / 91610196
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate5 / 18934526
salivary gland0 / 201550 
skin12 / 21057456
spleen9 / 53952166
stomach1 / 9661910
testis1 / 3304423
thymus6 / 8113173
thyroid3 / 4747363
tonsil2 / 16999117
trachea1 / 5241319
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204197_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts115.75
Adipocyte4.35
AdrenalCortex4.7
Adrenalgland3.7
Amygdala4.55
Appendix9.4
AtrioventricularNode3.55
BDCA4+_DentriticCells45
Bonemarrow14.3
BronchialEpithelialCells4.4
CD105+_Endothelial4.45
CD14+_Monocytes37.8
CD19+_BCells(neg._sel.)134.45
CD33+_Myeloid18.65
CD34+29.25
CD4+_Tcells195.75
CD56+_NKCells1808.4
CD71+_EarlyErythroid4.1
CD8+_Tcells324.15
CardiacMyocytes6.05
Caudatenucleus3.9
Cerebellum3.6
CerebellumPeduncles4.9
CiliaryGanglion3.5
CingulateCortex4.5
Colorectaladenocarcinoma7.5
DorsalRootGanglion3.45
FetalThyroid4.3
Fetalbrain4.4
Fetalliver3.75
Fetallung3.6
GlobusPallidus3.2
Heart6.4
Hypothalamus4.75
Kidney3.55
Leukemia_chronicMyelogenousK-5623.95
Leukemia_promyelocytic-HL-60120.9
Leukemialymphoblastic(MOLT-4)3.5
Liver5.75
Lung10.3
Lymphnode46.95
Lymphoma_burkitts(Daudi)9.15
Lymphoma_burkitts(Raji)15.2
MedullaOblongata4
OccipitalLobe3.95
OlfactoryBulb3.5
Ovary2.95
Pancreas3.95
PancreaticIslet4.7
ParietalLobe5.7
Pituitary5.15
Placenta4.5
Pons4.45
PrefrontalCortex5.4
Prostate5.15
Salivarygland10.65
SkeletalMuscle5.05
Skin8.95
SmoothMuscle5
Spinalcord4.65
SubthalamicNucleus4
SuperiorCervicalGanglion5.2
TemporalLobe4.25
Testis3.8
TestisGermCell3.6
TestisIntersitial3.65
TestisLeydigCell4.3
TestisSeminiferousTubule3.75
Thalamus4.45
Thymus8.15
Thyroid5.45
Tongue4.4
Tonsil68
Trachea4.25
TrigeminalGanglion4.8
Uterus3.65
UterusCorpus3.95
WholeBlood203.4
Wholebrain3.65
colon4.4
pineal_day6.56
pineal_night5.62
retina5.35
small_intestine4.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_17090_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.86 ± 0.89
Basal Forebrain2.1 ± 0.28
Basal Part of Pons2.41 ± 0.63
Cerebellar Cortex2.16 ± 0.65
Cerebellar Nuclei2.55 ± 0.7
Claustrum3.14 ± 0.97
Epithalamus2.11 ± 0.72
Frontal Lobe2.18 ± 0.7
Globus Pallidus3.21 ± 0.76
Hypothalamus2.16 ± 0.7
Insula2.43 ± 0.57
Limbic Lobe2.54 ± 0.69
Mesencephalon2.29 ± 0.78
Myelencephalon2.46 ± 0.78
Occipital Lobe2.56 ± 0.71
Parietal Lobe2.62 ± 0.82
Pontine Tegmentum2.33 ± 0.76
Striatum2.69 ± 0.93
Subthalamus2.12 ± 0.63
Temporal Lobe2.24 ± 0.77
Thalamus2.43 ± 0.69
White Matter2.56 ± 0.56
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00006592 17 12 28 RFTPPSPAFPCGGGGGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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