AutismKB 2.0

Annotation Detail for DCHS1


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Basic Information Top
Gene Symbol:DCHS1 ( CDH25,CDHR6,FIB1,FLJ11790,KIAA1773,PCDH16 )
Gene Full Name: dachsous 1 (Drosophila)
Band: 11p15.4
Quick LinksEntrez ID:8642; OMIM: 603057; Uniprot ID:PCD16_HUMAN; ENSEMBL ID: ENSG00000166341; HGNC ID: 13681
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus15 / 56401226
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult45 / 193912123
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor11 / 26384541
glioma5 / 10688346
head and neck tumor1 / 1363027
kidney tumor3 / 6895943
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal59 / 336030717
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma7 / 46356151
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain22 / 110098919
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye7 / 21105433
heart2 / 8962622
intestine5 / 23447221
kidney5 / 21177723
larynx0 / 241450 
liver0 / 2077430 
lung8 / 33697423
lymph0 / 442700 
lymph node0 / 916100 
mammary gland5 / 15327132
mouth1 / 6705214
muscle0 / 1077150 
nerve1 / 1576863
ovary1 / 1020519
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta9 / 28082532
prostate6 / 18934531
salivary gland0 / 201550 
skin1 / 2105744
spleen1 / 5395218
stomach3 / 9661931
testis3 / 3304429
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 222101_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.65
Adipocyte18.05
AdrenalCortex17.9
Adrenalgland25.5
Amygdala47.3
Appendix30.95
AtrioventricularNode26.5
BDCA4+_DentriticCells24.2
Bonemarrow16.4
BronchialEpithelialCells6.8
CD105+_Endothelial15.75
CD14+_Monocytes8.3
CD19+_BCells(neg._sel.)11.35
CD33+_Myeloid16.7
CD34+16.35
CD4+_Tcells24.2
CD56+_NKCells16.3
CD71+_EarlyErythroid10.6
CD8+_Tcells19.5
CardiacMyocytes22
Caudatenucleus28.35
Cerebellum31.4
CerebellumPeduncles35.9
CiliaryGanglion17.05
CingulateCortex28.2
Colorectaladenocarcinoma15.25
DorsalRootGanglion15.75
FetalThyroid30.1
Fetalbrain273.95
Fetalliver27.25
Fetallung83.45
GlobusPallidus12.05
Heart257.2
Hypothalamus38.7
Kidney21.4
Leukemia_chronicMyelogenousK-56216.4
Leukemia_promyelocytic-HL-6021.7
Leukemialymphoblastic(MOLT-4)31.35
Liver140.1
Lung149.1
Lymphnode27.7
Lymphoma_burkitts(Daudi)23.3
Lymphoma_burkitts(Raji)22.4
MedullaOblongata20.9
OccipitalLobe21.85
OlfactoryBulb11.2
Ovary27.55
Pancreas14.75
PancreaticIslet15.9
ParietalLobe39.3
Pituitary18.2
Placenta119.2
Pons34.05
PrefrontalCortex20.95
Prostate106.4
Salivarygland13.2
SkeletalMuscle28.55
Skin20.3
SmoothMuscle25.1
Spinalcord16.3
SubthalamicNucleus16.75
SuperiorCervicalGanglion24.25
TemporalLobe18.15
Testis84.3
TestisGermCell25.65
TestisIntersitial19.45
TestisLeydigCell22.65
TestisSeminiferousTubule25.7
Thalamus30.4
Thymus41.5
Thyroid25
Tongue18.1
Tonsil15.05
Trachea28.35
TrigeminalGanglion24.05
Uterus283.45
UterusCorpus152.6
WholeBlood16.9
Wholebrain31.05
colon77.1
pineal_day19.76
pineal_night20.06
retina40.7
small_intestine75.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_2180_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.91 ± 0.83
Basal Forebrain4.45 ± 0.37
Basal Part of Pons3.96 ± 0.6
Cerebellar Cortex4.14 ± 0.6
Cerebellar Nuclei4.22 ± 0.39
Claustrum4.1 ± 0.85
Epithalamus3.87 ± 1
Frontal Lobe3.84 ± 0.62
Globus Pallidus4.21 ± 0.85
Hypothalamus3.63 ± 0.85
Insula3.91 ± 0.5
Limbic Lobe4.09 ± 0.6
Mesencephalon3.97 ± 0.54
Myelencephalon4.01 ± 0.67
Occipital Lobe4.19 ± 0.53
Parietal Lobe3.98 ± 0.71
Pontine Tegmentum3.89 ± 0.66
Striatum4 ± 0.63
Subthalamus3.6 ± 0.47
Temporal Lobe3.84 ± 0.67
Thalamus4.01 ± 0.58
White Matter3.47 ± 1.33
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dchs1CBCerebellum0.64
1.13
Dchs1CTXCerebral cortex0.81
0.99
Dchs1HIPHippocampal region1.3
1.41
Dchs1HPFHippocampal formation0.87
0.89
Dchs1HYHypothalamus0.44
0.65
Dchs1LSXLateral septal complex1.48
2.3
Dchs1MBMidbrain0.3
0.44
Dchs1MYMedulla0.38
0.55
Dchs1OLFOlfactory bulb1.25
1.14
Dchs1PPons0.25
0.34
Dchs1PALPallidum0.33
0.26
Dchs1RHPRetrohippocampal region0.32
0.33
Dchs1sAMYStriatum-like amygdalar nuclei0.2
0.21
Dchs1STRStriatum0.62
0.85
Dchs1STRdStriatum dorsal region0.38
0.6
Dchs1STRvStriatum ventral region0.95
0.97
Dchs1THThalamus0.76
1.32
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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