AutismKB 2.0

Annotation Detail for EIF3G


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:EIF3G ( EIF3-P42,EIF3S4,eIF3-delta,eIF3-p44 )
Gene Full Name: eukaryotic translation initiation factor 3, subunit G
Band: 19p13.2
Quick LinksEntrez ID:8666; OMIM: 603913; Uniprot ID:EIF3G_HUMAN; ENSEMBL ID: ENSG00000130811; HGNC ID: 3274
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body19 / 70761268
blastocyst12 / 62319192
fetus30 / 56401253
neonate0 / 310970 
infant1 / 2362042
juvenile3 / 5555653
adult227 / 1939121117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor11 / 94178116
cervical tumor10 / 34366290
chondrosarcoma17 / 82823205
colorectal tumor14 / 114246122
esophageal tumor1 / 1729057
gastrointestinal tumor19 / 119369159
germ cell tumor37 / 263845140
glioma25 / 106883233
head and neck tumor13 / 13630295
kidney tumor7 / 68959101
leukemia10 / 95842104
liver tumor12 / 96359124
lung tumor36 / 103127349
lymphoma12 / 71755167
non-neoplasia5 / 9725051
normal283 / 336030784
ovarian tumor15 / 76682195
pancreatic tumor16 / 104616152
primitive neuroectodermal tumor of the CNS17 / 125680135
prostate cancer14 / 102680136
retinoblastoma9 / 46356194
skin tumor67 / 124949536
soft tissue/muscle tissue tumor18 / 125191143
uterine tumor17 / 90257188
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue5 / 13106381
adrenal gland1 / 3319730
ascites7 / 40015174
bladder8 / 29757268
blood4 / 12347832
bone10 / 71655139
bone marrow7 / 48801143
brain108 / 110098998
cervix14 / 48171290
connective tissue11 / 14925573
ear0 / 162120 
embryonic tissue38 / 215722176
esophagus1 / 2020949
eye27 / 211054127
heart4 / 8962644
intestine29 / 234472123
kidney20 / 21177794
larynx1 / 2414541
liver18 / 20774386
lung67 / 336974198
lymph8 / 44270180
lymph node3 / 9161032
mammary gland11 / 15327171
mouth2 / 6705229
muscle25 / 107715232
nerve3 / 15768190
ovary21 / 102051205
pancreas31 / 214812144
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland1 / 1658560
placenta29 / 280825103
prostate20 / 189345105
salivary gland20 / 20155992
skin72 / 210574341
spleen7 / 53952129
stomach10 / 96619103
testis25 / 33044275
thymus4 / 8113149
thyroid0 / 474730 
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus40 / 232878171
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208887_at
Cell line Expression level Expression bar
721_B_lymphoblasts711.8
Adipocyte218.4
AdrenalCortex173.9
Adrenalgland231.2
Amygdala169.4
Appendix143.35
AtrioventricularNode58.75
BDCA4+_DentriticCells840.6
Bonemarrow205.2
BronchialEpithelialCells384.4
CD105+_Endothelial435.55
CD14+_Monocytes944.4
CD19+_BCells(neg._sel.)1012.25
CD33+_Myeloid766.9
CD34+654.5
CD4+_Tcells1270.25
CD56+_NKCells1507.4
CD71+_EarlyErythroid225.4
CD8+_Tcells1036.3
CardiacMyocytes221.8
Caudatenucleus120.2
Cerebellum146.05
CerebellumPeduncles248.6
CiliaryGanglion36.65
CingulateCortex77.6
Colorectaladenocarcinoma392.05
DorsalRootGanglion61.85
FetalThyroid288.2
Fetalbrain136.8
Fetalliver140.1
Fetallung247.55
GlobusPallidus35.7
Heart750.1
Hypothalamus219.3
Kidney191.75
Leukemia_chronicMyelogenousK-562868.7
Leukemia_promyelocytic-HL-60314.05
Leukemialymphoblastic(MOLT-4)452.4
Liver694.85
Lung1218.45
Lymphnode359.15
Lymphoma_burkitts(Daudi)407.95
Lymphoma_burkitts(Raji)1115.45
MedullaOblongata80.65
OccipitalLobe87.35
OlfactoryBulb198.7
Ovary313.1
Pancreas270.9
PancreaticIslet261.75
ParietalLobe110.6
Pituitary284.55
Placenta286.1
Pons72.9
PrefrontalCortex147.9
Prostate916.3
Salivarygland141
SkeletalMuscle274.75
Skin102.55
SmoothMuscle535.35
Spinalcord204.55
SubthalamicNucleus36.75
SuperiorCervicalGanglion54.25
TemporalLobe117.6
Testis549.8
TestisGermCell373.4
TestisIntersitial387.5
TestisLeydigCell233.05
TestisSeminiferousTubule281.95
Thalamus179.15
Thymus663.65
Thyroid779
Tongue186.4
Tonsil281.75
Trachea202.85
TrigeminalGanglion75.05
Uterus513.6
UterusCorpus190.25
WholeBlood652.45
Wholebrain224.05
colon238.25
pineal_day192.36
pineal_night177.64
retina238.35
small_intestine239.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1089_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.67 ± 0.37
Basal Forebrain6.99 ± 0.2
Basal Part of Pons7.24 ± 0.39
Cerebellar Cortex7.16 ± 0.3
Cerebellar Nuclei6.99 ± 0.36
Claustrum6.77 ± 0.56
Epithalamus7.11 ± 0.44
Frontal Lobe7.07 ± 0.36
Globus Pallidus7.35 ± 0.13
Hypothalamus6.96 ± 0.22
Insula7.03 ± 0.23
Limbic Lobe6.86 ± 0.32
Mesencephalon6.89 ± 0.36
Myelencephalon6.96 ± 0.37
Occipital Lobe6.69 ± 0.33
Parietal Lobe6.93 ± 0.32
Pontine Tegmentum6.91 ± 0.3
Striatum6.79 ± 0.25
Subthalamus7.09 ± 0.41
Temporal Lobe6.99 ± 0.32
Thalamus6.95 ± 0.31
White Matter7.7 ± 0.43
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
EIF3G_HUMAN_173 8 173 180 DTLGPMQK PRIDE
EIF3G_HUMAN_180 29 180 208 ELAEQLGLSTGEKEKLPGELEPVQATQNK PRIDE
EIF3G_HUMAN_225 9 225 233 RGESMQPNR PRIDE
EIF3G_HUMAN_251 16 251 266 ETDLQELFRPFGSISR PRIDE
EIF3G_HUMAN_261 7 261 267 PFGSISR PRIDE
PAp00001289 12 169 180 CPYKDTLGPMQK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved