AutismKB 2.0

Annotation Detail for VAMP8


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Basic Information Top
Gene Symbol:VAMP8 ( EDB,VAMP-8 )
Gene Full Name: vesicle-associated membrane protein 8 (endobrevin)
Band: 2p11.2
Quick LinksEntrez ID:8673; OMIM: 603177; Uniprot ID:VAMP8_HUMAN; ENSEMBL ID: ENSG00000118640; HGNC ID: 12647
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst1 / 6231916
fetus30 / 56401253
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult112 / 193912157
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor3 / 9417831
cervical tumor2 / 3436658
chondrosarcoma4 / 8282348
colorectal tumor6 / 11424652
esophageal tumor1 / 1729057
gastrointestinal tumor9 / 11936975
germ cell tumor5 / 26384518
glioma5 / 10688346
head and neck tumor6 / 13630244
kidney tumor3 / 6895943
leukemia7 / 9584273
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma3 / 7175541
non-neoplasia0 / 972500 
normal144 / 336030742
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer5 / 10268048
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder2 / 2975767
blood24 / 123478194
bone2 / 7165527
bone marrow7 / 48801143
brain12 / 110098910
cervix4 / 4817183
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus1 / 2020949
eye7 / 21105433
heart0 / 896260 
intestine10 / 23447242
kidney8 / 21177737
larynx2 / 2414582
liver6 / 20774328
lung20 / 33697459
lymph1 / 4427022
lymph node7 / 9161076
mammary gland4 / 15327126
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary2 / 10205119
pancreas13 / 21481260
parathyroid0 / 205390 
pharynx7 / 41328169
pituitary gland6 / 16585361
placenta21 / 28082574
prostate12 / 18934563
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach8 / 9661982
testis0 / 3304420 
thymus1 / 8113112
thyroid4 / 4747384
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202546_at
Cell line Expression level Expression bar
721_B_lymphoblasts546.7
Adipocyte11.35
AdrenalCortex13.45
Adrenalgland34.9
Amygdala10.65
Appendix13.5
AtrioventricularNode15.2
BDCA4+_DentriticCells2428.8
Bonemarrow416.65
BronchialEpithelialCells1001.8
CD105+_Endothelial217.45
CD14+_Monocytes1417.5
CD19+_BCells(neg._sel.)601.05
CD33+_Myeloid1390.9
CD34+1785.85
CD4+_Tcells707.1
CD56+_NKCells1262.85
CD71+_EarlyErythroid70.55
CD8+_Tcells586.55
CardiacMyocytes28.6
Caudatenucleus14.25
Cerebellum15.45
CerebellumPeduncles13.95
CiliaryGanglion16.4
CingulateCortex10.55
Colorectaladenocarcinoma117.7
DorsalRootGanglion17.5
FetalThyroid107.6
Fetalbrain9.3
Fetalliver65.65
Fetallung345.05
GlobusPallidus10
Heart58.7
Hypothalamus15.9
Kidney334.8
Leukemia_chronicMyelogenousK-562305.75
Leukemia_promyelocytic-HL-60531.95
Leukemialymphoblastic(MOLT-4)7.9
Liver155.7
Lung528.55
Lymphnode326.7
Lymphoma_burkitts(Daudi)175.95
Lymphoma_burkitts(Raji)189.55
MedullaOblongata9.6
OccipitalLobe9.5
OlfactoryBulb24.2
Ovary17.1
Pancreas186.65
PancreaticIslet336.45
ParietalLobe12.25
Pituitary58
Placenta1015.85
Pons10.8
PrefrontalCortex7.25
Prostate221.7
Salivarygland321.15
SkeletalMuscle33.35
Skin91.2
SmoothMuscle15.1
Spinalcord35.9
SubthalamicNucleus7.25
SuperiorCervicalGanglion15.15
TemporalLobe10.45
Testis25.15
TestisGermCell20.05
TestisIntersitial34.75
TestisLeydigCell39.6
TestisSeminiferousTubule25.4
Thalamus19.15
Thymus298.55
Thyroid224
Tongue113
Tonsil481.3
Trachea323.45
TrigeminalGanglion15.25
Uterus15.25
UterusCorpus36.3
WholeBlood742.95
Wholebrain12.85
colon376.4
pineal_day19.34
pineal_night21
retina85.45
small_intestine472.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P49686
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.61 ± 1.21
Basal Forebrain1.97 ± 0.2
Basal Part of Pons1.65 ± 0.69
Cerebellar Cortex2.46 ± 0.84
Cerebellar Nuclei2.48 ± 0.93
Claustrum3.02 ± 1.03
Epithalamus1.72 ± 0.73
Frontal Lobe1.98 ± 0.96
Globus Pallidus2.53 ± 0.59
Hypothalamus2.26 ± 0.63
Insula1.73 ± 0.33
Limbic Lobe2.09 ± 0.75
Mesencephalon2.2 ± 0.77
Myelencephalon2.19 ± 0.74
Occipital Lobe2.38 ± 0.98
Parietal Lobe2.01 ± 0.8
Pontine Tegmentum2.22 ± 0.81
Striatum2.28 ± 0.85
Subthalamus2.3 ± 0.78
Temporal Lobe1.93 ± 0.7
Thalamus2.09 ± 0.76
White Matter2.16 ± 0.19
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Vamp8CBCerebellum0
0
Vamp8CTXCerebral cortex0
0
Vamp8HIPHippocampal region0
0
Vamp8HPFHippocampal formation0
0
Vamp8HYHypothalamus0
0
Vamp8LSXLateral septal complex0
0
Vamp8MBMidbrain0
0
Vamp8MYMedulla0
0
Vamp8OLFOlfactory bulb0
0
Vamp8PPons0
0
Vamp8PALPallidum0
0
Vamp8RHPRetrohippocampal region0
0
Vamp8sAMYStriatum-like amygdalar nuclei0
0
Vamp8STRStriatum0
0
Vamp8STRdStriatum dorsal region0
0
Vamp8STRvStriatum ventral region0
0
Vamp8THThalamus0
0
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00005843 14 46 59 NKTEDLEATSEHFK Peptide Atlas
VAMP8_HUMAN_0 0 0 0 NIMTQNVER PRIDE
VAMP8_HUMAN_0 0 0 0 NKTEDLEATSEHFK PRIDE
VAMP8_HUMAN_0 0 0 0 NLQSEVEGVK PRIDE
VAMP8_HUMAN_1 12 1 12 MEEASEGGGNDR PRIDE
VAMP8_HUMAN_14 10 14 23 NLQSEVEGVK PRIDE
VAMP8_HUMAN_14 19 14 32 NLQSEVEGVKNIMTQNVER PRIDE
VAMP8_HUMAN_24 9 24 32 NIMTQNVER PRIDE
VAMP8_HUMAN_45 14 45 58 NKTEDLEATSEHFK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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