AutismKB 2.0

Annotation Detail for MARCO


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MARCO ( SCARA2 )
Gene Full Name: macrophage receptor with collagenous structure
Band: 2q14.2
Quick LinksEntrez ID:8685; OMIM: 604870; Uniprot ID:MARCO_HUMAN; ENSEMBL ID: ENSG00000019169; HGNC ID: 6895
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus6 / 56401210
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult42 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor2 / 9635920
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia49 / 97250503
normal58 / 336030717
ovarian tumor3 / 7668239
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue4 / 13106305
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood7 / 12347856
bone0 / 716550 
bone marrow0 / 488010 
brain3 / 11009892
cervix0 / 481710 
connective tissue50 / 149255334
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart2 / 8962622
intestine5 / 23447221
kidney0 / 2117770 
larynx0 / 241450 
liver6 / 20774328
lung22 / 33697465
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary3 / 10205129
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta9 / 28082532
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205819_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.4
Adipocyte4.65
AdrenalCortex5.35
Adrenalgland3.85
Amygdala4.45
Appendix4.45
AtrioventricularNode3.45
BDCA4+_DentriticCells4.7
Bonemarrow4.4
BronchialEpithelialCells4.25
CD105+_Endothelial4.4
CD14+_Monocytes18.35
CD19+_BCells(neg._sel.)4.7
CD33+_Myeloid48.6
CD34+5.6
CD4+_Tcells4.65
CD56+_NKCells5.2
CD71+_EarlyErythroid4.15
CD8+_Tcells4.2
CardiacMyocytes5.65
Caudatenucleus3.9
Cerebellum3.55
CerebellumPeduncles5
CiliaryGanglion3.8
CingulateCortex4.5
Colorectaladenocarcinoma4.35
DorsalRootGanglion3.4
FetalThyroid4.2
Fetalbrain4.35
Fetalliver3.95
Fetallung8.1
GlobusPallidus3.25
Heart5.7
Hypothalamus4.75
Kidney3.65
Leukemia_chronicMyelogenousK-5623.95
Leukemia_promyelocytic-HL-603.85
Leukemialymphoblastic(MOLT-4)3.6
Liver6
Lung373.05
Lymphnode66.5
Lymphoma_burkitts(Daudi)5.65
Lymphoma_burkitts(Raji)6.2
MedullaOblongata4
OccipitalLobe3.95
OlfactoryBulb3.5
Ovary3.25
Pancreas3.55
PancreaticIslet4.7
ParietalLobe4.7
Pituitary5.1
Placenta4.55
Pons4.75
PrefrontalCortex5.45
Prostate5.05
Salivarygland3.55
SkeletalMuscle5.25
Skin4.05
SmoothMuscle4.9
Spinalcord4.8
SubthalamicNucleus4.3
SuperiorCervicalGanglion5.05
TemporalLobe4
Testis3.75
TestisGermCell3.6
TestisIntersitial3.8
TestisLeydigCell4.4
TestisSeminiferousTubule3.8
Thalamus4.5
Thymus3.5
Thyroid5.45
Tongue4.4
Tonsil4.25
Trachea3.85
TrigeminalGanglion4.5
Uterus3.55
UterusCorpus3.95
WholeBlood4.75
Wholebrain3.65
colon4.4
pineal_day5.46
pineal_night5.34
retina5.425
small_intestine4.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14053_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.57 ± 1.04
Basal Forebrain2.63 ± 0.72
Basal Part of Pons2.32 ± 0.79
Cerebellar Cortex3.13 ± 0.71
Cerebellar Nuclei3.17 ± 0.8
Claustrum2.6 ± 0.67
Epithalamus3.44 ± 0.58
Frontal Lobe2.57 ± 1.06
Globus Pallidus2.68 ± 0.87
Hypothalamus2.77 ± 1.27
Insula3.29 ± 1.19
Limbic Lobe2.63 ± 0.93
Mesencephalon2.78 ± 0.95
Myelencephalon2.59 ± 0.92
Occipital Lobe2.35 ± 0.75
Parietal Lobe2.26 ± 1
Pontine Tegmentum2.59 ± 0.82
Striatum2.83 ± 0.79
Subthalamus2.28 ± 0.89
Temporal Lobe2.53 ± 1.03
Thalamus2.67 ± 0.78
White Matter2.89 ± 0.96
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
MarcoCBCerebellum4.7
5.66
MarcoCTXCerebral cortex5.17
4.5
MarcoHIPHippocampal region2.9
3.25
MarcoHPFHippocampal formation3.21
3.05
MarcoHYHypothalamus10.19
9.3
MarcoLSXLateral septal complex1.62
1.07
MarcoMBMidbrain2.19
2.27
MarcoMYMedulla6.88
8.91
MarcoOLFOlfactory bulb6.35
5.47
MarcoPPons6.6
8.87
MarcoPALPallidum4.42
3.91
MarcoRHPRetrohippocampal region3.92
2.85
MarcosAMYStriatum-like amygdalar nuclei4.41
3.54
MarcoSTRStriatum1.38
1.46
MarcoSTRdStriatum dorsal region0.97
1.38
MarcoSTRvStriatum ventral region0.93
0.71
MarcoTHThalamus21.84
19.7
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00028343 12 134 145 VDNFTQNPGMFR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018