AutismKB 2.0

Annotation Detail for DGAT1


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Basic Information Top
Gene Symbol:DGAT1 ( ARGP1,DGAT )
Gene Full Name: diacylglycerol O-acyltransferase 1
Band: 8q24.3
Quick LinksEntrez ID:8694; OMIM: 604900; Uniprot ID:DGAT1_HUMAN; ENSEMBL ID: ENSG00000185000; HGNC ID: 2843
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus20 / 56401235
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult91 / 193912146
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor8 / 11424670
esophageal tumor0 / 172900 
gastrointestinal tumor20 / 119369167
germ cell tumor4 / 26384515
glioma12 / 106883112
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia10 / 95842104
liver tumor2 / 9635920
lung tumor4 / 10312738
lymphoma8 / 71755111
non-neoplasia0 / 972500 
normal114 / 336030733
ovarian tumor10 / 76682130
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer6 / 10268058
retinoblastoma1 / 4635621
skin tumor7 / 12494956
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites7 / 40015174
bladder0 / 297570 
blood18 / 123478145
bone0 / 716550 
bone marrow1 / 4880120
brain31 / 110098928
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye12 / 21105456
heart1 / 8962611
intestine19 / 23447281
kidney1 / 2117774
larynx1 / 2414541
liver5 / 20774324
lung11 / 33697432
lymph8 / 44270180
lymph node1 / 9161010
mammary gland8 / 15327152
mouth0 / 670520 
muscle2 / 10771518
nerve3 / 15768190
ovary13 / 102051127
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta13 / 28082546
prostate12 / 18934563
salivary gland1 / 2015549
skin7 / 21057433
spleen1 / 5395218
stomach17 / 96619175
testis5 / 33044215
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203669_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7
Adipocyte7.45
AdrenalCortex15.45
Adrenalgland23.2
Amygdala4.95
Appendix4.55
AtrioventricularNode3.45
BDCA4+_DentriticCells12.7
Bonemarrow4.5
BronchialEpithelialCells5.35
CD105+_Endothelial4.65
CD14+_Monocytes46.8
CD19+_BCells(neg._sel.)5.05
CD33+_Myeloid23.9
CD34+6.2
CD4+_Tcells5.2
CD56+_NKCells10.25
CD71+_EarlyErythroid9.25
CD8+_Tcells5.1
CardiacMyocytes5.7
Caudatenucleus4.1
Cerebellum3.65
CerebellumPeduncles5.2
CiliaryGanglion3.15
CingulateCortex4.6
Colorectaladenocarcinoma4.55
DorsalRootGanglion3.45
FetalThyroid4.5
Fetalbrain4.6
Fetalliver4
Fetallung3.7
GlobusPallidus3.4
Heart14.45
Hypothalamus4.8
Kidney3.65
Leukemia_chronicMyelogenousK-5624.2
Leukemia_promyelocytic-HL-604
Leukemialymphoblastic(MOLT-4)6.05
Liver31.7
Lung5.1
Lymphnode4.05
Lymphoma_burkitts(Daudi)5.75
Lymphoma_burkitts(Raji)6.35
MedullaOblongata4.05
OccipitalLobe4
OlfactoryBulb3.55
Ovary2.95
Pancreas9.5
PancreaticIslet4.85
ParietalLobe4.8
Pituitary5.2
Placenta4.65
Pons4.25
PrefrontalCortex6.15
Prostate5.2
Salivarygland3.7
SkeletalMuscle5.45
Skin3.45
SmoothMuscle5
Spinalcord4.9
SubthalamicNucleus4.25
SuperiorCervicalGanglion5.05
TemporalLobe4.15
Testis25.5
TestisGermCell15.5
TestisIntersitial4.35
TestisLeydigCell7.5
TestisSeminiferousTubule10.75
Thalamus4.65
Thymus3.75
Thyroid6.55
Tongue4.5
Tonsil4.4
Trachea3.75
TrigeminalGanglion4.55
Uterus3.75
UterusCorpus4.05
WholeBlood7
Wholebrain4.05
colon26.5
pineal_day7.08
pineal_night6.16
retina5.575
small_intestine244.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_3350_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.41 ± 0.66
Basal Forebrain2.9 ± 0.44
Basal Part of Pons3.14 ± 0.5
Cerebellar Cortex3.5 ± 0.4
Cerebellar Nuclei3.1 ± 0.52
Claustrum3.6 ± 0.67
Epithalamus2.65 ± 0.58
Frontal Lobe3.04 ± 0.62
Globus Pallidus2.84 ± 0.66
Hypothalamus3.06 ± 0.41
Insula2.9 ± 0.63
Limbic Lobe3.2 ± 0.59
Mesencephalon3.2 ± 0.66
Myelencephalon3.11 ± 0.6
Occipital Lobe3.26 ± 0.64
Parietal Lobe3.03 ± 0.55
Pontine Tegmentum3.01 ± 0.65
Striatum3.05 ± 0.68
Subthalamus3.24 ± 0.68
Temporal Lobe3.11 ± 0.63
Thalamus3.01 ± 0.65
White Matter3.06 ± 0.84
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00515968 21 33 53 DAAAGPDVGAAGDAPAPAPNK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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