AutismKB 2.0

Annotation Detail for DNAH11


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Basic Information Top
Gene Symbol:DNAH11 ( CILD7,DNAHBL,DNAHC11,DNHBL,DPL11,FLJ30095,FLJ37699 )
Gene Full Name: dynein, axonemal, heavy chain 11
Band: 7p15.3
Quick LinksEntrez ID:8701; OMIM: 603339; Uniprot ID:DYH11_HUMAN; ENSEMBL ID: ENSG00000105877; HGNC ID: 2942
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult44 / 193912122
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor2 / 3436658
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma3 / 10688328
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor5 / 10312748
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal29 / 33603078
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder1 / 2975733
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain6 / 11009895
cervix2 / 4817141
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus1 / 2020949
eye0 / 2110540 
heart1 / 8962611
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver3 / 20774314
lung7 / 33697420
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid16 / 20539779
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta7 / 28082524
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis7 / 33044221
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P224253
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.1 ± 1.22
Basal Forebrain1.48 ± 0.23
Basal Part of Pons1.27 ± 0.4
Cerebellar Cortex1.81 ± 0.71
Cerebellar Nuclei1.82 ± 0.9
Claustrum2.47 ± 0.72
Epithalamus5.58 ± 1.4
Frontal Lobe1.47 ± 1.17
Globus Pallidus1.76 ± 0.87
Hypothalamus1.55 ± 0.78
Insula1.32 ± 0.53
Limbic Lobe1.65 ± 0.79
Mesencephalon1.99 ± 1.17
Myelencephalon1.81 ± 1.25
Occipital Lobe1.82 ± 1.11
Parietal Lobe1.53 ± 0.84
Pontine Tegmentum1.52 ± 0.81
Striatum2.73 ± 1.81
Subthalamus1.56 ± 0.55
Temporal Lobe1.55 ± 0.87
Thalamus1.42 ± 0.63
White Matter1.89 ± 0.42
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dnahc11CBCerebellum0.37
0.72
Dnahc11CTXCerebral cortex0.56
0.8
Dnahc11HIPHippocampal region0.16
0.4
Dnahc11HPFHippocampal formation0.12
0.24
Dnahc11HYHypothalamus0.17
0.18
Dnahc11LSXLateral septal complex1.44
1.8
Dnahc11MBMidbrain0.08
0.16
Dnahc11MYMedulla1.03
1.31
Dnahc11OLFOlfactory bulb6.66
5.48
Dnahc11PPons0.23
0.22
Dnahc11PALPallidum0.12
0.24
Dnahc11RHPRetrohippocampal region0.07
0.07
Dnahc11sAMYStriatum-like amygdalar nuclei0.22
0.33
Dnahc11STRStriatum0.37
0.5
Dnahc11STRdStriatum dorsal region0.25
0.29
Dnahc11STRvStriatum ventral region0.45
0.73
Dnahc11THThalamus0.32
0.38
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018