AutismKB 2.0

Annotation Detail for NOL4


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:NOL4 ( CT125,NOLP )
Gene Full Name: nucleolar protein 4
Band: 18q12.1
Quick LinksEntrez ID:8715; OMIM: 603577; Uniprot ID:NOL4_HUMAN; ENSEMBL ID: ENSG00000101746; HGNC ID: 7870
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus61 / 564012108
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult25 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor17 / 103127164
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal108 / 336030732
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain76 / 110098969
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye6 / 21105428
heart0 / 896260 
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung25 / 33697474
lymph0 / 442700 
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary0 / 1020510 
pancreas13 / 21481260
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis11 / 33044233
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206045_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts25
Adipocyte4.35
AdrenalCortex4.75
Adrenalgland3.75
Amygdala5.2
Appendix4.5
AtrioventricularNode3.65
BDCA4+_DentriticCells4.4
Bonemarrow4.35
BronchialEpithelialCells4.25
CD105+_Endothelial4.45
CD14+_Monocytes4.55
CD19+_BCells(neg._sel.)4.45
CD33+_Myeloid5.25
CD34+5.2
CD4+_Tcells4.55
CD56+_NKCells5.25
CD71+_EarlyErythroid4.1
CD8+_Tcells4
CardiacMyocytes5.6
Caudatenucleus3.9
Cerebellum3.55
CerebellumPeduncles5.35
CiliaryGanglion3.15
CingulateCortex18.7
Colorectaladenocarcinoma4.35
DorsalRootGanglion3.4
FetalThyroid4.25
Fetalbrain11.45
Fetalliver3.8
Fetallung3.45
GlobusPallidus7.65
Heart6
Hypothalamus5.05
Kidney3.6
Leukemia_chronicMyelogenousK-5623.95
Leukemia_promyelocytic-HL-603.85
Leukemialymphoblastic(MOLT-4)3.35
Liver6.1
Lung4.7
Lymphnode3.65
Lymphoma_burkitts(Daudi)5.55
Lymphoma_burkitts(Raji)6.15
MedullaOblongata6.8
OccipitalLobe12.15
OlfactoryBulb3.45
Ovary2.9
Pancreas3.5
PancreaticIslet11.75
ParietalLobe4.75
Pituitary5.1
Placenta4.25
Pons4.45
PrefrontalCortex5.55
Prostate5.1
Salivarygland3.55
SkeletalMuscle5.5
Skin3.55
SmoothMuscle4.95
Spinalcord4.65
SubthalamicNucleus7.05
SuperiorCervicalGanglion5.1
TemporalLobe4.05
Testis3.8
TestisGermCell6.1
TestisIntersitial27
TestisLeydigCell5
TestisSeminiferousTubule6.25
Thalamus4.45
Thymus3.25
Thyroid5.3
Tongue4.25
Tonsil4.25
Trachea3.65
TrigeminalGanglion4.5
Uterus3.55
UterusCorpus4.15
WholeBlood4.65
Wholebrain5.7
colon4.3
pineal_day71.64
pineal_night71.28
retina5.2
small_intestine4.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P126733
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.91 ± 0.47
Basal Forebrain8.41 ± 0.38
Basal Part of Pons7.76 ± 0.49
Cerebellar Cortex8.66 ± 0.11
Cerebellar Nuclei6.92 ± 0.58
Claustrum8.68 ± 0.35
Epithalamus7.75 ± 0.7
Frontal Lobe8.54 ± 0.58
Globus Pallidus6.57 ± 0.67
Hypothalamus8.55 ± 0.65
Insula9 ± 0.36
Limbic Lobe8.7 ± 0.51
Mesencephalon8.32 ± 0.72
Myelencephalon8.32 ± 0.62
Occipital Lobe7.93 ± 0.52
Parietal Lobe8.33 ± 0.47
Pontine Tegmentum8.3 ± 0.69
Striatum7.71 ± 0.77
Subthalamus7.74 ± 0.18
Temporal Lobe8.71 ± 0.37
Thalamus8.36 ± 0.49
White Matter5.6 ± 0.13
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nol4CBCerebellum10.09
12.39
Nol4CTXCerebral cortex68.4
37.36
Nol4HIPHippocampal region17.63
16.69
Nol4HPFHippocampal formation27.38
18.41
Nol4HYHypothalamus4.56
2.65
Nol4LSXLateral septal complex14.11
6.17
Nol4MBMidbrain1.36
0.7
Nol4MYMedulla2.33
2.51
Nol4OLFOlfactory bulb49.21
26.59
Nol4PPons1.06
0.97
Nol4PALPallidum1.04
0.49
Nol4RHPRetrohippocampal region39.73
20.57
Nol4sAMYStriatum-like amygdalar nuclei27.15
12.1
Nol4STRStriatum7.19
3.12
Nol4STRdStriatum dorsal region4.06
1.6
Nol4STRvStriatum ventral region3
1.26
Nol4THThalamus2.33
2.12
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved