AutismKB 2.0

Annotation Detail for RNMT


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Basic Information Top
Gene Symbol:RNMT ( DKFZp686H1252,KIAA0398,MET,RG7MT1,hCMT1c )
Gene Full Name: RNA (guanine-7-) methyltransferase
Band: 18p11.21
Quick LinksEntrez ID:8731; OMIM: 603514; Uniprot ID:MCES_HUMAN; ENSEMBL ID: ENSG00000101654; HGNC ID: 10075
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst4 / 6231964
fetus29 / 56401251
neonate0 / 310970 
infant1 / 2362042
juvenile3 / 5555653
adult102 / 193912152
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor6 / 11424652
esophageal tumor1 / 1729057
gastrointestinal tumor8 / 11936967
germ cell tumor12 / 26384545
glioma4 / 10688337
head and neck tumor19 / 136302139
kidney tumor3 / 6895943
leukemia4 / 9584241
liver tumor7 / 9635972
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia4 / 9725041
normal153 / 336030745
ovarian tumor4 / 7668252
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor9 / 12494972
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites6 / 40015149
bladder0 / 297570 
blood7 / 12347856
bone6 / 7165583
bone marrow2 / 4880140
brain35 / 110098931
cervix5 / 48171103
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue18 / 21572283
esophagus1 / 2020949
eye3 / 21105414
heart3 / 8962633
intestine13 / 23447255
kidney14 / 21177766
larynx1 / 2414541
liver22 / 207743105
lung14 / 33697441
lymph1 / 4427022
lymph node5 / 9161054
mammary gland16 / 153271104
mouth11 / 67052164
muscle5 / 10771546
nerve1 / 1576863
ovary5 / 10205148
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta7 / 28082524
prostate4 / 18934521
salivary gland0 / 201550 
skin9 / 21057442
spleen0 / 539520 
stomach0 / 966190 
testis17 / 33044251
thymus4 / 8113149
thyroid9 / 47473189
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus4 / 23287817
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202683_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts85.8
Adipocyte13.35
AdrenalCortex15.9
Adrenalgland11.15
Amygdala40.5
Appendix16.85
AtrioventricularNode10.9
BDCA4+_DentriticCells25.15
Bonemarrow13.5
BronchialEpithelialCells14.15
CD105+_Endothelial31.6
CD14+_Monocytes14.45
CD19+_BCells(neg._sel.)23.55
CD33+_Myeloid20.3
CD34+29.7
CD4+_Tcells26.85
CD56+_NKCells31.3
CD71+_EarlyErythroid12.85
CD8+_Tcells25.25
CardiacMyocytes18.6
Caudatenucleus20.6
Cerebellum12.15
CerebellumPeduncles15.9
CiliaryGanglion10.3
CingulateCortex33.35
Colorectaladenocarcinoma14.2
DorsalRootGanglion11.3
FetalThyroid17.15
Fetalbrain34.4
Fetalliver11.95
Fetallung11.15
GlobusPallidus21.15
Heart17.85
Hypothalamus43.75
Kidney11.4
Leukemia_chronicMyelogenousK-56234.65
Leukemia_promyelocytic-HL-6050.45
Leukemialymphoblastic(MOLT-4)25.6
Liver18.15
Lung12.65
Lymphnode25.25
Lymphoma_burkitts(Daudi)22.6
Lymphoma_burkitts(Raji)19.45
MedullaOblongata42.05
OccipitalLobe16.15
OlfactoryBulb10.85
Ovary8.9
Pancreas9.9
PancreaticIslet19.05
ParietalLobe18.4
Pituitary18.55
Placenta14.5
Pons14.6
PrefrontalCortex79.7
Prostate15.15
Salivarygland16.75
SkeletalMuscle17
Skin11.25
SmoothMuscle13.95
Spinalcord26.4
SubthalamicNucleus46.05
SuperiorCervicalGanglion16.15
TemporalLobe19.1
Testis18.35
TestisGermCell12.25
TestisIntersitial11.45
TestisLeydigCell13.05
TestisSeminiferousTubule13.6
Thalamus30.45
Thymus12.05
Thyroid21.9
Tongue13.7
Tonsil15.45
Trachea11.35
TrigeminalGanglion14.1
Uterus11.7
UterusCorpus13
WholeBlood15.2
Wholebrain13.7
colon13.65
pineal_day50.92
pineal_night50.62
retina18.525
small_intestine13.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P55515
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.13 ± 0.17
Basal Forebrain9.02 ± 0.14
Basal Part of Pons9.38 ± 0.25
Cerebellar Cortex9.11 ± 0.22
Cerebellar Nuclei9.12 ± 0.32
Claustrum9.2 ± 0.32
Epithalamus8.98 ± 0.37
Frontal Lobe9.33 ± 0.29
Globus Pallidus8.81 ± 0.34
Hypothalamus9.58 ± 0.25
Insula9.38 ± 0.29
Limbic Lobe9.19 ± 0.33
Mesencephalon9.24 ± 0.32
Myelencephalon9.15 ± 0.31
Occipital Lobe9.09 ± 0.31
Parietal Lobe9.32 ± 0.3
Pontine Tegmentum9.24 ± 0.33
Striatum8.91 ± 0.27
Subthalamus9.7 ± 0.37
Temporal Lobe9.24 ± 0.25
Thalamus9.2 ± 0.28
White Matter8.84 ± 0.17
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
RnmtCBCerebellum53.94
62.68
RnmtCTXCerebral cortex100
100
RnmtHIPHippocampal region79.4
100
RnmtHPFHippocampal formation88.94
100
RnmtHYHypothalamus68.87
61.86
RnmtLSXLateral septal complex99.98
81.17
RnmtMBMidbrain87.29
87.46
RnmtMYMedulla83.69
100
RnmtOLFOlfactory bulb88.22
87.47
RnmtPPons75.28
90.4
RnmtPALPallidum71.86
71.64
RnmtRHPRetrohippocampal region100
100
RnmtsAMYStriatum-like amygdalar nuclei78.21
65.69
RnmtSTRStriatum84.89
65.83
RnmtSTRdStriatum dorsal region84.47
64.62
RnmtSTRvStriatum ventral region85.43
62.35
RnmtTHThalamus97.2
91.28
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00010889 12 223 234 LVCTDIADVSVK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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