AutismKB 2.0

Annotation Detail for ADAM9


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Basic Information Top
Gene Symbol:ADAM9 ( CORD9,KIAA0021,MCMP,MDC9,Mltng )
Gene Full Name: ADAM metallopeptidase domain 9
Band: 8p11.22
Quick LinksEntrez ID:8754; OMIM: 602713; Uniprot ID:ADAM9_HUMAN; ENSEMBL ID: ENSG00000168615; HGNC ID: 216
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body11 / 70761155
blastocyst0 / 623190 
fetus9 / 56401215
neonate1 / 3109732
infant0 / 236200 
juvenile3 / 5555653
adult152 / 193912178
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor5 / 9417853
cervical tumor1 / 3436629
chondrosarcoma11 / 82823132
colorectal tumor12 / 114246105
esophageal tumor2 / 17290115
gastrointestinal tumor25 / 119369209
germ cell tumor8 / 26384530
glioma4 / 10688337
head and neck tumor8 / 13630258
kidney tumor6 / 6895987
leukemia4 / 9584241
liver tumor6 / 9635962
lung tumor5 / 10312748
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal136 / 336030740
ovarian tumor5 / 7668265
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer17 / 102680165
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites3 / 4001574
bladder3 / 29757100
blood4 / 12347832
bone9 / 71655125
bone marrow1 / 4880120
brain24 / 110098921
cervix2 / 4817141
connective tissue17 / 149255113
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus2 / 2020998
eye5 / 21105423
heart4 / 8962644
intestine18 / 23447276
kidney12 / 21177756
larynx3 / 24145124
liver7 / 20774333
lung23 / 33697468
lymph0 / 442700 
lymph node1 / 9161010
mammary gland20 / 153271130
mouth2 / 6705229
muscle4 / 10771537
nerve2 / 15768126
ovary3 / 10205129
pancreas13 / 21481260
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta9 / 28082532
prostate24 / 189345126
salivary gland0 / 201550 
skin12 / 21057456
spleen0 / 539520 
stomach20 / 96619206
testis11 / 33044233
thymus0 / 811310 
thyroid3 / 4747363
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord1 / 1368073
uterus5 / 23287821
vascular14 / 51780270
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202381_at
Cell line Expression level Expression bar
721_B_lymphoblasts132.85
Adipocyte218.25
AdrenalCortex23.45
Adrenalgland17.25
Amygdala137.65
Appendix44.55
AtrioventricularNode26.95
BDCA4+_DentriticCells57.35
Bonemarrow20.7
BronchialEpithelialCells1126.15
CD105+_Endothelial27.9
CD14+_Monocytes102.3
CD19+_BCells(neg._sel.)16.8
CD33+_Myeloid273.05
CD34+21.7
CD4+_Tcells14.65
CD56+_NKCells12.8
CD71+_EarlyErythroid17.2
CD8+_Tcells11.2
CardiacMyocytes666.9
Caudatenucleus22.3
Cerebellum17.5
CerebellumPeduncles26.55
CiliaryGanglion24.95
CingulateCortex27.5
Colorectaladenocarcinoma330.3
DorsalRootGanglion24.7
FetalThyroid58.45
Fetalbrain25.8
Fetalliver33.35
Fetallung170.3
GlobusPallidus12.9
Heart34
Hypothalamus63.75
Kidney17.5
Leukemia_chronicMyelogenousK-56228.1
Leukemia_promyelocytic-HL-6025.7
Leukemialymphoblastic(MOLT-4)10.2
Liver24
Lung18.45
Lymphnode26.5
Lymphoma_burkitts(Daudi)21.1
Lymphoma_burkitts(Raji)46.7
MedullaOblongata13.3
OccipitalLobe25.7
OlfactoryBulb24
Ovary28.25
Pancreas35.75
PancreaticIslet96.75
ParietalLobe19.2
Pituitary20.55
Placenta27.85
Pons16.2
PrefrontalCortex32.4
Prostate90.75
Salivarygland32.25
SkeletalMuscle30.65
Skin19.25
SmoothMuscle1497.2
Spinalcord37.35
SubthalamicNucleus20.4
SuperiorCervicalGanglion35.35
TemporalLobe15.7
Testis10.4
TestisGermCell41.7
TestisIntersitial19.15
TestisLeydigCell20.65
TestisSeminiferousTubule15
Thalamus20.5
Thymus9.8
Thyroid382.8
Tongue21.05
Tonsil15.85
Trachea112.3
TrigeminalGanglion28.05
Uterus151.8
UterusCorpus29.75
WholeBlood26.05
Wholebrain21.45
colon490.45
pineal_day78.98
pineal_night116.26
retina71.6
small_intestine238.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P72643
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.88 ± 0.61
Basal Forebrain6.13 ± 0.21
Basal Part of Pons6.33 ± 0.29
Cerebellar Cortex6.35 ± 0.26
Cerebellar Nuclei6.19 ± 0.3
Claustrum5.9 ± 0.65
Epithalamus6.32 ± 0.39
Frontal Lobe6.09 ± 0.34
Globus Pallidus6.41 ± 0.37
Hypothalamus6.1 ± 0.22
Insula5.86 ± 0.43
Limbic Lobe5.88 ± 0.43
Mesencephalon6.05 ± 0.57
Myelencephalon5.99 ± 0.42
Occipital Lobe6.17 ± 0.47
Parietal Lobe6.19 ± 0.42
Pontine Tegmentum6.12 ± 0.43
Striatum5.52 ± 0.32
Subthalamus6.6 ± 0.19
Temporal Lobe6.08 ± 0.36
Thalamus6.05 ± 0.38
White Matter6.71 ± 0.07
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Adam9CBCerebellum3.13
2.9
Adam9CTXCerebral cortex2.98
0.84
Adam9HIPHippocampal region2.18
1.67
Adam9HPFHippocampal formation1.75
1.09
Adam9HYHypothalamus0.47
0.19
Adam9LSXLateral septal complex0.16
0.72
Adam9MBMidbrain1.34
0.73
Adam9MYMedulla9.97
6
Adam9OLFOlfactory bulb1.14
0.45
Adam9PPons4.72
2.71
Adam9PALPallidum0.27
0.09
Adam9RHPRetrohippocampal region1.04
0.32
Adam9sAMYStriatum-like amygdalar nuclei0.59
0.62
Adam9STRStriatum0.32
0.42
Adam9STRdStriatum dorsal region0.29
0.2
Adam9STRvStriatum ventral region0.26
0.94
Adam9THThalamus0.4
0.18
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ADAM9_HUMAN_185 18 185 202 ETAKDEEEEPPSMTQLLR PRIDE
PAp00010210 23 398 420 GGNCLLNIPKPDEAYSAPSCGNK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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