AutismKB 2.0

Annotation Detail for RAB11A


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Basic Information Top
Gene Symbol:RAB11A ( MGC1490,YL8 )
Gene Full Name: RAB11A, member RAS oncogene family
Band: 15q22.31
Quick LinksEntrez ID:8766; OMIM: 605570; Uniprot ID:RB11A_HUMAN; ENSEMBL ID: ENSG00000103769; HGNC ID: 9760
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body10 / 70761141
blastocyst8 / 62319128
fetus155 / 564012274
neonate15 / 31097482
infant7 / 23620296
juvenile14 / 55556251
adult311 / 1939121160
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor4 / 12794312
bladder carcinoma10 / 17475572
breast (mammary gland) tumor9 / 9417895
cervical tumor1 / 3436629
chondrosarcoma13 / 82823156
colorectal tumor16 / 114246140
esophageal tumor6 / 17290347
gastrointestinal tumor15 / 119369125
germ cell tumor40 / 263845151
glioma8 / 10688374
head and neck tumor19 / 136302139
kidney tumor14 / 68959203
leukemia9 / 9584293
liver tumor5 / 9635951
lung tumor4 / 10312738
lymphoma3 / 7175541
non-neoplasia12 / 97250123
normal715 / 3360307212
ovarian tumor8 / 76682104
pancreatic tumor16 / 104616152
primitive neuroectodermal tumor of the CNS21 / 125680167
prostate cancer21 / 102680204
retinoblastoma7 / 46356151
skin tumor15 / 124949120
soft tissue/muscle tissue tumor43 / 125191343
uterine tumor11 / 90257121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue4 / 13106305
adrenal gland9 / 33197271
ascites6 / 40015149
bladder17 / 29757571
blood13 / 123478105
bone15 / 71655209
bone marrow7 / 48801143
brain311 / 1100989282
cervix1 / 4817120
connective tissue47 / 149255314
ear8 / 16212493
embryonic tissue36 / 215722166
esophagus6 / 20209296
eye31 / 211054146
heart27 / 89626301
intestine39 / 234472166
kidney34 / 211777160
larynx1 / 2414541
liver11 / 20774352
lung36 / 336974106
lymph1 / 4427022
lymph node11 / 91610120
mammary gland14 / 15327191
mouth15 / 67052223
muscle7 / 10771564
nerve2 / 15768126
ovary12 / 102051117
pancreas54 / 214812251
parathyroid6 / 20539292
pharynx6 / 41328145
pituitary gland7 / 16585422
placenta34 / 280825121
prostate36 / 189345190
salivary gland1 / 2015549
skin52 / 210574246
spleen22 / 53952407
stomach17 / 96619175
testis74 / 330442223
thymus8 / 8113198
thyroid7 / 47473147
tonsil0 / 169990 
trachea21 / 52413400
umbilical cord5 / 13680365
uterus51 / 232878218
vascular26 / 51780502
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200864_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts44.85
Adipocyte13.8
AdrenalCortex26.95
Adrenalgland36.55
Amygdala71.45
Appendix17.4
AtrioventricularNode14.3
BDCA4+_DentriticCells50.35
Bonemarrow16.6
BronchialEpithelialCells60.8
CD105+_Endothelial19.1
CD14+_Monocytes37.3
CD19+_BCells(neg._sel.)32.7
CD33+_Myeloid37.15
CD34+50.65
CD4+_Tcells15.25
CD56+_NKCells28.15
CD71+_EarlyErythroid13.65
CD8+_Tcells20.1
CardiacMyocytes22.6
Caudatenucleus18.3
Cerebellum12
CerebellumPeduncles20.95
CiliaryGanglion12.4
CingulateCortex19.6
Colorectaladenocarcinoma14.75
DorsalRootGanglion13.9
FetalThyroid21.35
Fetalbrain131.9
Fetalliver14.2
Fetallung27.15
GlobusPallidus12.5
Heart21.25
Hypothalamus68.9
Kidney14.3
Leukemia_chronicMyelogenousK-56219.05
Leukemia_promyelocytic-HL-6018.2
Leukemialymphoblastic(MOLT-4)11.2
Liver21.05
Lung18.25
Lymphnode14.35
Lymphoma_burkitts(Daudi)23.45
Lymphoma_burkitts(Raji)22.05
MedullaOblongata15.5
OccipitalLobe42.1
OlfactoryBulb13.1
Ovary11.25
Pancreas19.4
PancreaticIslet37.7
ParietalLobe17.5
Pituitary25.75
Placenta43.25
Pons14.5
PrefrontalCortex75.4
Prostate20.35
Salivarygland12.05
SkeletalMuscle20.45
Skin14.25
SmoothMuscle24.2
Spinalcord23.55
SubthalamicNucleus14.5
SuperiorCervicalGanglion22.1
TemporalLobe20.75
Testis19.05
TestisGermCell27.35
TestisIntersitial13.3
TestisLeydigCell15.05
TestisSeminiferousTubule12.3
Thalamus23.05
Thymus13.9
Thyroid62.85
Tongue18.65
Tonsil17.15
Trachea44.4
TrigeminalGanglion19.65
Uterus58.05
UterusCorpus14.05
WholeBlood61.45
Wholebrain24.35
colon177.4
pineal_day113.78
pineal_night112.22
retina69.95
small_intestine212.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P124957
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.73 ± 0.41
Basal Forebrain8.5 ± 0.29
Basal Part of Pons9.05 ± 0.22
Cerebellar Cortex8.88 ± 0.28
Cerebellar Nuclei8.9 ± 0.31
Claustrum8.28 ± 0.41
Epithalamus8.54 ± 0.47
Frontal Lobe9.02 ± 0.36
Globus Pallidus8.5 ± 0.34
Hypothalamus8.91 ± 0.54
Insula9 ± 0.29
Limbic Lobe8.85 ± 0.45
Mesencephalon8.73 ± 0.4
Myelencephalon8.77 ± 0.45
Occipital Lobe8.47 ± 0.39
Parietal Lobe8.79 ± 0.38
Pontine Tegmentum8.89 ± 0.43
Striatum8.37 ± 0.33
Subthalamus9.19 ± 0.39
Temporal Lobe8.91 ± 0.33
Thalamus8.81 ± 0.28
White Matter8.12 ± 0.35
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rab11aCBCerebellum2.65
4.33
Rab11aCTXCerebral cortex1.13
1.44
Rab11aHIPHippocampal region0.59
0.52
Rab11aHPFHippocampal formation0.51
0.43
Rab11aHYHypothalamus0.12
0.07
Rab11aLSXLateral septal complex0.1
0.12
Rab11aMBMidbrain1.38
1.52
Rab11aMYMedulla1.61
1.98
Rab11aOLFOlfactory bulb2.01
3.83
Rab11aPPons1.03
1.38
Rab11aPALPallidum0.35
0.26
Rab11aRHPRetrohippocampal region0.4
0.31
Rab11asAMYStriatum-like amygdalar nuclei0.03
0
Rab11aSTRStriatum0.15
0.22
Rab11aSTRdStriatum dorsal region0.19
0.27
Rab11aSTRvStriatum ventral region0.1
0.21
Rab11aTHThalamus0.61
1.06
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00003445 9 96 104 HLTYENVER Peptide Atlas
RB11A_HUMAN_0 0 0 0 GAVGALLVYDIAK PRIDE
RB11A_HUMAN_0 0 0 0 STIGVEFATR PRIDE
RB11A_HUMAN_0 0 0 0 VVLIGDSGVGK PRIDE
RB11A_HUMAN_110 15 110 124 DHADSNIVIMLVGNK PRIDE
RB11A_HUMAN_111 15 111 125 DHADSNIVIMLVGNK PRIDE
RB11A_HUMAN_13 11 13 23 VVLIGDSGVGK PRIDE
RB11A_HUMAN_30 11 30 40 FTRNEFNLESK PRIDE
RB11A_HUMAN_4 9 4 12 DDEYDYLFK PRIDE
RB11A_HUMAN_41 10 41 50 STIGVEFATR PRIDE
RB11A_HUMAN_58 14 58 71 TIKAQIWDTAGQER PRIDE
RB11A_HUMAN_61 11 61 71 AQIWDTAGQER PRIDE
RB11A_HUMAN_74 8 74 81 AITSAYYR PRIDE
RB11A_HUMAN_82 13 82 94 GAVGALLVYDIAK PRIDE
RB11A_HUMAN_95 9 95 103 HLTYENVER PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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