AutismKB 2.0

Annotation Detail for FBP2


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Basic Information Top
Gene Symbol:FBP2 ( MGC142192 )
Gene Full Name: fructose-1,6-bisphosphatase 2
Band: 9q22.32
Quick LinksEntrez ID:8789; OMIM: 603027; Uniprot ID:F16P2_HUMAN; ENSEMBL ID: ENSG00000130957; HGNC ID: 3607
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult19 / 19391219
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal18 / 33603075
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain4 / 11009893
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart4 / 8962644
intestine1 / 2344724
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle10 / 10771592
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206844_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.4
Adipocyte4.5
AdrenalCortex4.85
Adrenalgland4
Amygdala4.8
Appendix4.6
AtrioventricularNode3.6
BDCA4+_DentriticCells4.85
Bonemarrow4.7
BronchialEpithelialCells4.5
CD105+_Endothelial4.5
CD14+_Monocytes4.9
CD19+_BCells(neg._sel.)4.8
CD33+_Myeloid5.65
CD34+5.7
CD4+_Tcells4.85
CD56+_NKCells5.35
CD71+_EarlyErythroid4.25
CD8+_Tcells4.3
CardiacMyocytes5.8
Caudatenucleus4.1
Cerebellum3.7
CerebellumPeduncles5.2
CiliaryGanglion3.2
CingulateCortex4.7
Colorectaladenocarcinoma4.55
DorsalRootGanglion3.55
FetalThyroid4.4
Fetalbrain4.45
Fetalliver4
Fetallung3.7
GlobusPallidus3.35
Heart6.2
Hypothalamus4.8
Kidney3.85
Leukemia_chronicMyelogenousK-5624.1
Leukemia_promyelocytic-HL-604
Leukemialymphoblastic(MOLT-4)3.6
Liver6.65
Lung4.95
Lymphnode3.85
Lymphoma_burkitts(Daudi)5.75
Lymphoma_burkitts(Raji)6.45
MedullaOblongata4.1
OccipitalLobe4.1
OlfactoryBulb3.6
Ovary3.1
Pancreas3.7
PancreaticIslet4.9
ParietalLobe4.75
Pituitary5.3
Placenta4.7
Pons6.3
PrefrontalCortex5.55
Prostate5.25
Salivarygland3.7
SkeletalMuscle49.5
Skin3.55
SmoothMuscle5.1
Spinalcord4.9
SubthalamicNucleus4.05
SuperiorCervicalGanglion5.4
TemporalLobe4.2
Testis4.65
TestisGermCell3.8
TestisIntersitial3.75
TestisLeydigCell4.55
TestisSeminiferousTubule3.9
Thalamus4.65
Thymus3.55
Thyroid5.7
Tongue10.7
Tonsil4.4
Trachea3.85
TrigeminalGanglion4.8
Uterus3.7
UterusCorpus4.1
WholeBlood4.95
Wholebrain4.65
colon4.6
pineal_day5.64
pineal_night6.76
retina5.5
small_intestine5.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8045_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.14 ± 1.05
Basal Forebrain1.78 ± 0.23
Basal Part of Pons1.48 ± 0.4
Cerebellar Cortex1.74 ± 0.93
Cerebellar Nuclei2.03 ± 0.73
Claustrum2.68 ± 0.91
Epithalamus1.64 ± 0.89
Frontal Lobe1.57 ± 0.71
Globus Pallidus2.3 ± 0.63
Hypothalamus1.92 ± 0.74
Insula1.55 ± 0.47
Limbic Lobe1.79 ± 0.69
Mesencephalon1.91 ± 0.71
Myelencephalon1.82 ± 0.75
Occipital Lobe1.98 ± 0.96
Parietal Lobe1.8 ± 0.76
Pontine Tegmentum1.86 ± 0.84
Striatum1.91 ± 0.76
Subthalamus1.99 ± 0.49
Temporal Lobe1.66 ± 0.62
Thalamus1.75 ± 0.7
White Matter2.76 ± 0.68
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fbp2CBCerebellum0.23
0.91
Fbp2CTXCerebral cortex0.41
1.54
Fbp2HIPHippocampal region0.54
1.7
Fbp2HPFHippocampal formation0.51
1.86
Fbp2HYHypothalamus1.45
2.17
Fbp2LSXLateral septal complex0.07
0
Fbp2MBMidbrain0.6
1.73
Fbp2MYMedulla0.41
1.49
Fbp2OLFOlfactory bulb1.93
5.08
Fbp2PPons2.95
7.99
Fbp2PALPallidum0.69
1.11
Fbp2RHPRetrohippocampal region0.36
2.23
Fbp2sAMYStriatum-like amygdalar nuclei0.44
1
Fbp2STRStriatum0.28
0.49
Fbp2STRdStriatum dorsal region0.06
0.1
Fbp2STRvStriatum ventral region1.03
1.47
Fbp2THThalamus0.15
0.14
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
F16P2_HUMAN_0 0 0 0 IYSLNEGYAK PRIDE
F16P2_HUMAN_0 0 0 0 TLVYGGIFLYPANQK PRIDE
F16P2_HUMAN_0 0 0 0 YVGSMVADVHR PRIDE
F16P2_HUMAN_5 12 5 16 SPFETDMLTLTR PRIDE
PAp00566447 11 245 255 YVGSMVADVHR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018