AutismKB 2.0

Annotation Detail for TNFRSF10D


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Basic Information Top
Gene Symbol:TNFRSF10D ( CD264,DCR2,TRAILR4,TRUNDD )
Gene Full Name: tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
Band: 8p21.3
Quick LinksEntrez ID:8793; OMIM: 603614; Uniprot ID:TR10D_HUMAN; ENSEMBL ID: ENSG00000173530; HGNC ID: 11907
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst7 / 62319112
fetus17 / 56401230
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult26 / 193912113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor6 / 26384522
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal68 / 336030720
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer9 / 10268087
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain2 / 11009891
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue13 / 21572260
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine9 / 23447238
kidney6 / 21177728
larynx1 / 2414541
liver4 / 20774319
lung2 / 3369745
lymph0 / 442700 
lymph node1 / 9161010
mammary gland2 / 15327113
mouth1 / 6705214
muscle5 / 10771546
nerve0 / 157680 
ovary0 / 1020510 
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta3 / 28082510
prostate12 / 18934563
salivary gland0 / 201550 
skin5 / 21057423
spleen0 / 539520 
stomach2 / 9661920
testis5 / 33044215
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular2 / 5178038
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210654_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.75
Adipocyte4.45
AdrenalCortex4.7
Adrenalgland3.8
Amygdala4.65
Appendix4.7
AtrioventricularNode3.7
BDCA4+_DentriticCells4.75
Bonemarrow4.45
BronchialEpithelialCells4.5
CD105+_Endothelial4.6
CD14+_Monocytes4.75
CD19+_BCells(neg._sel.)4.75
CD33+_Myeloid5.65
CD34+5.55
CD4+_Tcells5
CD56+_NKCells5.2
CD71+_EarlyErythroid4.25
CD8+_Tcells4.3
CardiacMyocytes8.4
Caudatenucleus4
Cerebellum3.65
CerebellumPeduncles5.2
CiliaryGanglion3.2
CingulateCortex4.65
Colorectaladenocarcinoma4.55
DorsalRootGanglion3.5
FetalThyroid4.4
Fetalbrain4.4
Fetalliver3.9
Fetallung3.7
GlobusPallidus3.35
Heart5.7
Hypothalamus4.8
Kidney3.7
Leukemia_chronicMyelogenousK-5624.1
Leukemia_promyelocytic-HL-604
Leukemialymphoblastic(MOLT-4)3.6
Liver6.05
Lung4.95
Lymphnode3.9
Lymphoma_burkitts(Daudi)5.75
Lymphoma_burkitts(Raji)6.35
MedullaOblongata4.1
OccipitalLobe4.05
OlfactoryBulb3.55
Ovary3
Pancreas3.7
PancreaticIslet4.85
ParietalLobe4.85
Pituitary5.25
Placenta4.7
Pons4.3
PrefrontalCortex5.5
Prostate5.25
Salivarygland3.65
SkeletalMuscle5.55
Skin3.55
SmoothMuscle5.15
Spinalcord4.8
SubthalamicNucleus4.2
SuperiorCervicalGanglion5.4
TemporalLobe4.15
Testis3.9
TestisGermCell3.8
TestisIntersitial3.8
TestisLeydigCell4.5
TestisSeminiferousTubule3.9
Thalamus4.65
Thymus3.55
Thyroid5.6
Tongue4.6
Tonsil4.35
Trachea3.75
TrigeminalGanglion4.45
Uterus3.65
UterusCorpus4.15
WholeBlood4.9
Wholebrain3.75
colon4.55
pineal_day5.56
pineal_night5.46
retina5.425
small_intestine4.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15528_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala1.63 ± 0.92
Basal Forebrain1.11 ± 0.2
Basal Part of Pons0.98 ± 0.65
Cerebellar Cortex1.1 ± 0.73
Cerebellar Nuclei1.54 ± 0.88
Claustrum2.02 ± 0.74
Epithalamus1.18 ± 0.62
Frontal Lobe1.07 ± 0.65
Globus Pallidus2.01 ± 0.55
Hypothalamus1.34 ± 0.89
Insula1.08 ± 0.68
Limbic Lobe1.28 ± 0.77
Mesencephalon1.49 ± 0.79
Myelencephalon1.28 ± 0.65
Occipital Lobe1.36 ± 0.62
Parietal Lobe1.38 ± 0.78
Pontine Tegmentum1.34 ± 0.72
Striatum1.39 ± 0.56
Subthalamus1.3 ± 0.59
Temporal Lobe1.16 ± 0.62
Thalamus1.26 ± 0.67
White Matter1.78 ± 0.44
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018