AutismKB 2.0

Annotation Detail for TNFRSF10C


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Basic Information Top
Gene Symbol:TNFRSF10C ( CD263,DCR1,DCR1-TNFR,LIT,MGC149501,MGC149502,TRAIL-R3,TRAILR3,TRID )
Gene Full Name: tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
Band: 8p21.3
Quick LinksEntrez ID:8794; OMIM: 603613; Uniprot ID:TR10C_HUMAN; ENSEMBL ID: ENSG00000173535; HGNC ID: 11906
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus2 / 5640123
neonate3 / 3109796
infant0 / 236200 
juvenile0 / 555560 
adult22 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor6 / 26384522
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia10 / 95842104
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal62 / 336030718
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood49 / 123478396
bone0 / 716550 
bone marrow0 / 488010 
brain1 / 11009890 
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney5 / 21177723
larynx0 / 241450 
liver2 / 2077439
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate0 / 1893450 
salivary gland0 / 201550 
skin1 / 2105744
spleen1 / 5395218
stomach0 / 966190 
testis3 / 3304429
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord3 / 13680219
uterus4 / 23287817
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210484_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts21.55
Adipocyte23.45
AdrenalCortex39.95
Adrenalgland18.7
Amygdala13.15
Appendix18.55
AtrioventricularNode51.5
BDCA4+_DentriticCells18.65
Bonemarrow25.2
BronchialEpithelialCells14.05
CD105+_Endothelial16.35
CD14+_Monocytes19.35
CD19+_BCells(neg._sel.)19.05
CD33+_Myeloid24.3
CD34+22.25
CD4+_Tcells20.55
CD56+_NKCells21.9
CD71+_EarlyErythroid18.15
CD8+_Tcells16.2
CardiacMyocytes25
Caudatenucleus28.25
Cerebellum15.45
CerebellumPeduncles33.8
CiliaryGanglion26.1
CingulateCortex33.3
Colorectaladenocarcinoma16.5
DorsalRootGanglion32.1
FetalThyroid18.7
Fetalbrain19.85
Fetalliver15.9
Fetallung15.5
GlobusPallidus41.15
Heart24.1
Hypothalamus20.95
Kidney24.9
Leukemia_chronicMyelogenousK-56217.85
Leukemia_promyelocytic-HL-6017.15
Leukemialymphoblastic(MOLT-4)15.1
Liver24.5
Lung15.55
Lymphnode19.25
Lymphoma_burkitts(Daudi)28.6
Lymphoma_burkitts(Raji)26.3
MedullaOblongata23.05
OccipitalLobe17.7
OlfactoryBulb20
Ovary20.95
Pancreas16.45
PancreaticIslet21.4
ParietalLobe27.95
Pituitary23.15
Placenta20
Pons34.95
PrefrontalCortex21.55
Prostate16.95
Salivarygland26.15
SkeletalMuscle32.4
Skin36.85
SmoothMuscle25.2
Spinalcord25.45
SubthalamicNucleus51.05
SuperiorCervicalGanglion38.85
TemporalLobe26.95
Testis15.3
TestisGermCell15.2
TestisIntersitial16.85
TestisLeydigCell24.85
TestisSeminiferousTubule19.6
Thalamus46.3
Thymus12.7
Thyroid15.55
Tongue26.45
Tonsil18.8
Trachea18.1
TrigeminalGanglion25.4
Uterus10.3
UterusCorpus16.5
WholeBlood555.8
Wholebrain8.65
colon16.4
pineal_day22
pineal_night22.94
retina20
small_intestine14.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12986_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.26 ± 1.12
Basal Forebrain1.62 ± 0.23
Basal Part of Pons1.39 ± 0.4
Cerebellar Cortex1.62 ± 0.8
Cerebellar Nuclei2.16 ± 0.74
Claustrum2.52 ± 1.04
Epithalamus1.64 ± 0.69
Frontal Lobe1.62 ± 0.74
Globus Pallidus2.38 ± 0.41
Hypothalamus1.78 ± 0.91
Insula1.5 ± 0.53
Limbic Lobe1.86 ± 0.74
Mesencephalon1.96 ± 0.93
Myelencephalon1.87 ± 0.78
Occipital Lobe1.87 ± 0.78
Parietal Lobe2.04 ± 1.19
Pontine Tegmentum1.88 ± 0.84
Striatum1.94 ± 0.62
Subthalamus2.22 ± 1
Temporal Lobe1.7 ± 0.74
Thalamus1.77 ± 0.82
White Matter2.37 ± 0.83
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018