AutismKB 2.0

Annotation Detail for TNFRSF10A


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Basic Information Top
Gene Symbol:TNFRSF10A ( APO2,CD261,DR4,MGC9365,TRAILR-1,TRAILR1 )
Gene Full Name: tumor necrosis factor receptor superfamily, member 10a
Band: 8p21.3
Quick LinksEntrez ID:8797; OMIM: 603611; Uniprot ID:TR10A_HUMAN; ENSEMBL ID: ENSG00000104689; HGNC ID: 11904
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult18 / 19391219
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor4 / 26384515
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia3 / 9725030
normal16 / 33603074
ovarian tumor7 / 7668291
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer8 / 10268077
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood3 / 12347824
bone0 / 716550 
bone marrow0 / 488010 
brain1 / 11009890 
cervix1 / 4817120
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine1 / 2344724
kidney1 / 2117774
larynx0 / 241450 
liver1 / 2077434
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth2 / 6705229
muscle0 / 1077150 
nerve0 / 157680 
ovary7 / 10205168
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate8 / 18934542
salivary gland0 / 201550 
skin2 / 2105749
spleen2 / 5395237
stomach0 / 966190 
testis1 / 3304423
thymus4 / 8113149
thyroid0 / 474730 
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus2 / 2328788
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15757_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.38 ± 0.49
Basal Forebrain4.79 ± 0.63
Basal Part of Pons4.56 ± 0.38
Cerebellar Cortex4.73 ± 0.57
Cerebellar Nuclei4.71 ± 0.64
Claustrum5.06 ± 0.74
Epithalamus4.43 ± 0.36
Frontal Lobe4.38 ± 0.58
Globus Pallidus4.63 ± 0.68
Hypothalamus4 ± 0.71
Insula4.29 ± 0.44
Limbic Lobe4.57 ± 0.62
Mesencephalon4.5 ± 0.68
Myelencephalon4.54 ± 0.6
Occipital Lobe4.76 ± 0.55
Parietal Lobe4.55 ± 0.6
Pontine Tegmentum4.5 ± 0.7
Striatum4.55 ± 0.57
Subthalamus5.32 ± 0.57
Temporal Lobe4.5 ± 0.61
Thalamus4.46 ± 0.61
White Matter5.78 ± 0.44
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018