AutismKB 2.0

Annotation Detail for DCAF5


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Basic Information Top
Gene Symbol:DCAF5 ( BCRG2,BCRP2,D14S1461E,DKFZp434A035,KIAA1824,WDR22 )
Gene Full Name: DDB1 and CUL4 associated factor 5
Band: 14q24.1
Quick LinksEntrez ID:8816; OMIM: 603812; Uniprot ID:DCAF5_HUMAN; ENSEMBL ID: ENSG00000139990; HGNC ID: 20224
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst3 / 6231948
fetus56 / 56401299
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult111 / 193912157
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor2 / 3436658
chondrosarcoma5 / 8282360
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor10 / 26384537
glioma8 / 10688374
head and neck tumor5 / 13630236
kidney tumor1 / 6895914
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor8 / 10312777
lymphoma3 / 7175541
non-neoplasia4 / 9725041
normal232 / 336030769
ovarian tumor2 / 7668226
pancreatic tumor11 / 104616105
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer1 / 1026809
retinoblastoma3 / 4635664
skin tumor2 / 12494916
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites2 / 4001549
bladder1 / 2975733
blood1 / 1234788
bone5 / 7165569
bone marrow5 / 48801102
brain43 / 110098939
cervix2 / 4817141
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue16 / 21572274
esophagus0 / 202090 
eye26 / 211054123
heart10 / 89626111
intestine8 / 23447234
kidney7 / 21177733
larynx1 / 2414541
liver3 / 20774314
lung39 / 336974115
lymph1 / 4427022
lymph node11 / 91610120
mammary gland5 / 15327132
mouth2 / 6705229
muscle5 / 10771546
nerve0 / 157680 
ovary4 / 10205139
pancreas29 / 214812135
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta7 / 28082524
prostate10 / 18934552
salivary gland0 / 201550 
skin14 / 21057466
spleen0 / 539520 
stomach1 / 9661910
testis49 / 330442148
thymus1 / 8113112
thyroid4 / 4747384
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus14 / 23287860
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P117346
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.93 ± 0.39
Basal Forebrain9.07 ± 0.11
Basal Part of Pons8.89 ± 0.2
Cerebellar Cortex9.27 ± 0.23
Cerebellar Nuclei8.81 ± 0.23
Claustrum8.68 ± 0.23
Epithalamus9.32 ± 0.33
Frontal Lobe9.09 ± 0.25
Globus Pallidus8.88 ± 0.1
Hypothalamus8.94 ± 0.26
Insula9.17 ± 0.19
Limbic Lobe9.17 ± 0.27
Mesencephalon9.02 ± 0.24
Myelencephalon9.04 ± 0.24
Occipital Lobe9.11 ± 0.21
Parietal Lobe9.02 ± 0.25
Pontine Tegmentum9.04 ± 0.25
Striatum9 ± 0.26
Subthalamus8.82 ± 0.33
Temporal Lobe9.11 ± 0.24
Thalamus9.04 ± 0.22
White Matter8.86 ± 0.12
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Wdr22CBCerebellum2.51
2.39
Wdr22CTXCerebral cortex10.51
7.5
Wdr22HIPHippocampal region6.96
7.29
Wdr22HPFHippocampal formation7.84
7.24
Wdr22HYHypothalamus0.18
0.14
Wdr22LSXLateral septal complex0.27
0.23
Wdr22MBMidbrain1.95
2.61
Wdr22MYMedulla1.39
1.63
Wdr22OLFOlfactory bulb5.49
4.36
Wdr22PPons2.23
2.78
Wdr22PALPallidum0.54
0.66
Wdr22RHPRetrohippocampal region9.34
7.24
Wdr22sAMYStriatum-like amygdalar nuclei0.39
0.29
Wdr22STRStriatum0.51
0.41
Wdr22STRdStriatum dorsal region0.51
0.45
Wdr22STRvStriatum ventral region0.59
0.39
Wdr22THThalamus1.28
1.23
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018