AutismKB 2.0

Annotation Detail for NRP2


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Basic Information Top
Gene Symbol:NRP2 ( MGC126574,NP2,NPN2,PRO2714,VEGF165R2 )
Gene Full Name: neuropilin 2
Band: 2q33.3
Quick LinksEntrez ID:8828; OMIM: 602070; Uniprot ID:NRP2_HUMAN; ENSEMBL ID: ENSG00000118257; HGNC ID: 8005
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst4 / 6231964
fetus78 / 564012138
neonate4 / 31097128
infant2 / 2362084
juvenile1 / 5555617
adult153 / 193912178
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor4 / 11424635
esophageal tumor1 / 1729057
gastrointestinal tumor7 / 11936958
germ cell tumor28 / 263845106
glioma4 / 10688337
head and neck tumor12 / 13630288
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor4 / 9635941
lung tumor1 / 1031279
lymphoma2 / 7175527
non-neoplasia8 / 9725082
normal247 / 336030773
ovarian tumor26 / 76682339
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor6 / 12494948
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone6 / 7165583
bone marrow1 / 4880120
brain22 / 110098919
cervix0 / 481710 
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue15 / 21572269
esophagus1 / 2020949
eye27 / 211054127
heart15 / 89626167
intestine11 / 23447246
kidney13 / 21177761
larynx2 / 2414582
liver6 / 20774328
lung36 / 336974106
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth8 / 67052119
muscle4 / 10771537
nerve2 / 15768126
ovary30 / 102051293
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta16 / 28082556
prostate2 / 18934510
salivary gland0 / 201550 
skin35 / 210574166
spleen0 / 539520 
stomach7 / 9661972
testis13 / 33044239
thymus3 / 8113136
thyroid2 / 4747342
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord3 / 13680219
uterus22 / 23287894
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210841_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.45
Adipocyte8.3
AdrenalCortex12.55
Adrenalgland10.25
Amygdala8.7
Appendix8.65
AtrioventricularNode7.85
BDCA4+_DentriticCells7.6
Bonemarrow8.85
BronchialEpithelialCells8.15
CD105+_Endothelial8.3
CD14+_Monocytes8.55
CD19+_BCells(neg._sel.)8.4
CD33+_Myeloid10.35
CD34+9.4
CD4+_Tcells8.25
CD56+_NKCells9
CD71+_EarlyErythroid7.6
CD8+_Tcells7
CardiacMyocytes10.4
Caudatenucleus7.65
Cerebellum6.95
CerebellumPeduncles10.5
CiliaryGanglion6.75
CingulateCortex8.95
Colorectaladenocarcinoma8.1
DorsalRootGanglion7.8
FetalThyroid8.15
Fetalbrain8.6
Fetalliver7.4
Fetallung6.85
GlobusPallidus6.05
Heart10.5
Hypothalamus8.8
Kidney8.65
Leukemia_chronicMyelogenousK-5627.5
Leukemia_promyelocytic-HL-607.35
Leukemialymphoblastic(MOLT-4)6.8
Liver11.1
Lung9.2
Lymphnode7.35
Lymphoma_burkitts(Daudi)10.85
Lymphoma_burkitts(Raji)11.6
MedullaOblongata11.25
OccipitalLobe7.5
OlfactoryBulb6.75
Ovary5.65
Pancreas6.85
PancreaticIslet9.4
ParietalLobe12.75
Pituitary14
Placenta8.35
Pons14.75
PrefrontalCortex9.6
Prostate9.4
Salivarygland7
SkeletalMuscle20.2
Skin6.65
SmoothMuscle9.15
Spinalcord8.95
SubthalamicNucleus8.35
SuperiorCervicalGanglion13.25
TemporalLobe9.4
Testis8.4
TestisGermCell7.15
TestisIntersitial7.55
TestisLeydigCell8.85
TestisSeminiferousTubule8.75
Thalamus8.45
Thymus6.75
Thyroid9.9
Tongue10.2
Tonsil8.3
Trachea7.6
TrigeminalGanglion9.75
Uterus6.8
UterusCorpus8.45
WholeBlood9.35
Wholebrain6.8
colon8.15
pineal_day9.7
pineal_night9.5
retina10
small_intestine7.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9796_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.64 ± 0.99
Basal Forebrain2.24 ± 0.59
Basal Part of Pons2.01 ± 1.1
Cerebellar Cortex2.03 ± 1.04
Cerebellar Nuclei2.46 ± 0.62
Claustrum3.25 ± 1.28
Epithalamus2.1 ± 0.78
Frontal Lobe2.09 ± 0.81
Globus Pallidus2.87 ± 0.41
Hypothalamus2.15 ± 0.82
Insula1.79 ± 0.5
Limbic Lobe2.25 ± 0.81
Mesencephalon2.37 ± 0.91
Myelencephalon2.17 ± 0.73
Occipital Lobe2.19 ± 0.75
Parietal Lobe2.14 ± 0.95
Pontine Tegmentum2.23 ± 0.72
Striatum2.29 ± 0.71
Subthalamus2.44 ± 0.39
Temporal Lobe2.07 ± 0.75
Thalamus2.19 ± 0.75
White Matter2.88 ± 1.07
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
NRP2_HUMAN_335 16 335 350 FLTMLTAIATQGAISR PRIDE
PAp00538636 16 288 303 IANEQISASSTYSDGR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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