AutismKB 2.0

Annotation Detail for NRP1


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Basic Information Top
Gene Symbol:NRP1 ( BDCA4,CD304,DKFZp686A03134,DKFZp781F1414,NP1,NRP,VEGF165R )
Gene Full Name: neuropilin 1
Band: 10p11.22
Quick LinksEntrez ID:8829; OMIM: 602069; Uniprot ID:NRP1_HUMAN; ENSEMBL ID: ENSG00000099250; HGNC ID: 8004
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus42 / 56401274
neonate4 / 31097128
infant0 / 236200 
juvenile4 / 5555671
adult161 / 193912183
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor12 / 94178127
cervical tumor1 / 3436629
chondrosarcoma12 / 82823144
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor11 / 26384541
glioma18 / 106883168
head and neck tumor13 / 13630295
kidney tumor10 / 68959145
leukemia0 / 958420 
liver tumor7 / 9635972
lung tumor6 / 10312758
lymphoma1 / 7175513
non-neoplasia4 / 9725041
normal234 / 336030769
ovarian tumor1 / 7668213
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor12 / 12519195
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites2 / 4001549
bladder1 / 2975733
blood2 / 12347816
bone14 / 71655195
bone marrow2 / 4880140
brain64 / 110098958
cervix1 / 4817120
connective tissue22 / 149255147
ear5 / 16212308
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye6 / 21105428
heart5 / 8962655
intestine11 / 23447246
kidney25 / 211777118
larynx3 / 24145124
liver17 / 20774381
lung24 / 33697471
lymph0 / 442700 
lymph node1 / 9161010
mammary gland17 / 153271110
mouth7 / 67052104
muscle20 / 107715185
nerve2 / 15768126
ovary5 / 10205148
pancreas14 / 21481265
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta20 / 28082571
prostate7 / 18934536
salivary gland0 / 201550 
skin6 / 21057428
spleen6 / 53952111
stomach5 / 9661951
testis2 / 3304426
thymus11 / 81131135
thyroid2 / 4747342
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord3 / 13680219
uterus26 / 232878111
vascular23 / 51780444
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210510_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.1
Adipocyte8.75
AdrenalCortex7.15
Adrenalgland5.7
Amygdala6.8
Appendix7.45
AtrioventricularNode4.9
BDCA4+_DentriticCells15.9
Bonemarrow6.75
BronchialEpithelialCells6.4
CD105+_Endothelial6.4
CD14+_Monocytes6.8
CD19+_BCells(neg._sel.)6.95
CD33+_Myeloid7.75
CD34+8.25
CD4+_Tcells6.5
CD56+_NKCells7.1
CD71+_EarlyErythroid6.05
CD8+_Tcells5.7
CardiacMyocytes141.6
Caudatenucleus5.85
Cerebellum5.3
CerebellumPeduncles7.7
CiliaryGanglion5.05
CingulateCortex6.6
Colorectaladenocarcinoma6.45
DorsalRootGanglion4.95
FetalThyroid6.35
Fetalbrain6.45
Fetalliver6
Fetallung8.75
GlobusPallidus4.85
Heart8.6
Hypothalamus7.1
Kidney5.75
Leukemia_chronicMyelogenousK-5625.9
Leukemia_promyelocytic-HL-605.75
Leukemialymphoblastic(MOLT-4)5.15
Liver9.2
Lung8.65
Lymphnode5.65
Lymphoma_burkitts(Daudi)8.3
Lymphoma_burkitts(Raji)9.25
MedullaOblongata6
OccipitalLobe5.85
OlfactoryBulb5.1
Ovary5.55
Pancreas5.2
PancreaticIslet6.95
ParietalLobe6.95
Pituitary7.6
Placenta19.55
Pons6.25
PrefrontalCortex8.05
Prostate7.55
Salivarygland5.25
SkeletalMuscle8.1
Skin4.95
SmoothMuscle127.85
Spinalcord6.95
SubthalamicNucleus5.9
SuperiorCervicalGanglion7.6
TemporalLobe5.95
Testis5.65
TestisGermCell5.4
TestisIntersitial5.4
TestisLeydigCell6.45
TestisSeminiferousTubule5.6
Thalamus6.7
Thymus5.2
Thyroid8.2
Tongue6.6
Tonsil6.35
Trachea5.5
TrigeminalGanglion6.4
Uterus5.4
UterusCorpus6.3
WholeBlood7.05
Wholebrain5.25
colon6.5
pineal_day7.98
pineal_night7.64
retina8
small_intestine6.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P86390
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.09 ± 0.63
Basal Forebrain7.89 ± 0.39
Basal Part of Pons7.84 ± 0.36
Cerebellar Cortex7.47 ± 0.63
Cerebellar Nuclei7.82 ± 0.54
Claustrum7.95 ± 0.65
Epithalamus7.15 ± 0.58
Frontal Lobe8.1 ± 0.72
Globus Pallidus8.99 ± 0.54
Hypothalamus7.36 ± 0.36
Insula8.02 ± 0.56
Limbic Lobe8.66 ± 0.66
Mesencephalon7.76 ± 0.55
Myelencephalon8.1 ± 0.67
Occipital Lobe7.96 ± 0.8
Parietal Lobe8 ± 0.66
Pontine Tegmentum7.96 ± 0.65
Striatum8.03 ± 0.77
Subthalamus7.04 ± 0.59
Temporal Lobe7.83 ± 0.7
Thalamus8.03 ± 0.47
White Matter8.23 ± 0.19
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nrp1CBCerebellum1.15
2.46
Nrp1CTXCerebral cortex4.3
3.52
Nrp1HIPHippocampal region39.45
76.32
Nrp1HPFHippocampal formation30.23
48.24
Nrp1HYHypothalamus1.05
0.83
Nrp1LSXLateral septal complex8.03
6.3
Nrp1MBMidbrain1.06
1.54
Nrp1MYMedulla3.01
5.45
Nrp1OLFOlfactory bulb3.54
3.45
Nrp1PPons1.84
3.61
Nrp1PALPallidum0.66
0.49
Nrp1RHPRetrohippocampal region18.44
18.09
Nrp1sAMYStriatum-like amygdalar nuclei1.79
1.67
Nrp1STRStriatum1.05
0.87
Nrp1STRdStriatum dorsal region0.24
0.22
Nrp1STRvStriatum ventral region0.65
0.52
Nrp1THThalamus3.17
5.99
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000954 13 54 66 CEWLIQAPDPYQR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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