AutismKB 2.0

Annotation Detail for WISP3


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Basic Information Top
Gene Symbol:WISP3 ( CCN6,LIBC,MGC125987,MGC125988,MGC125989,PPAC,PPD )
Gene Full Name: WNT1 inducible signaling pathway protein 3
Band: 6q21
Quick LinksEntrez ID:8838; OMIM: 603400; Uniprot ID:WISP3_HUMAN; ENSEMBL ID: ENSG00000112761; HGNC ID: 12771
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult2 / 19391211
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal5 / 33603071
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder3 / 29757100
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue2 / 14925513
ear2 / 16212123
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210861_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.9
Adipocyte6
AdrenalCortex7.3
Adrenalgland5.45
Amygdala6.15
Appendix7.95
AtrioventricularNode5.6
BDCA4+_DentriticCells6.1
Bonemarrow6.55
BronchialEpithelialCells6.05
CD105+_Endothelial6.1
CD14+_Monocytes6.5
CD19+_BCells(neg._sel.)6.35
CD33+_Myeloid7.65
CD34+7.55
CD4+_Tcells6.4
CD56+_NKCells6.9
CD71+_EarlyErythroid5.8
CD8+_Tcells5.55
CardiacMyocytes9
Caudatenucleus5.45
Cerebellum4.95
CerebellumPeduncles7.4
CiliaryGanglion4.9
CingulateCortex6.45
Colorectaladenocarcinoma6.2
DorsalRootGanglion6.05
FetalThyroid6.1
Fetalbrain5.95
Fetalliver5.45
Fetallung4.8
GlobusPallidus4.75
Heart9.15
Hypothalamus6.4
Kidney5.45
Leukemia_chronicMyelogenousK-5625.5
Leukemia_promyelocytic-HL-605.45
Leukemialymphoblastic(MOLT-4)4.8
Liver8.9
Lung6.7
Lymphnode5.15
Lymphoma_burkitts(Daudi)8.9
Lymphoma_burkitts(Raji)9.4
MedullaOblongata5.75
OccipitalLobe5.45
OlfactoryBulb4.8
Ovary4.4
Pancreas5.05
PancreaticIslet6.7
ParietalLobe6.9
Pituitary7.15
Placenta6.15
Pons6.05
PrefrontalCortex7.3
Prostate7.05
Salivarygland5.7
SkeletalMuscle8.2
Skin5.85
SmoothMuscle6.9
Spinalcord6.55
SubthalamicNucleus5.8
SuperiorCervicalGanglion23.6
TemporalLobe5.7
Testis5.25
TestisGermCell5.6
TestisIntersitial5.3
TestisLeydigCell6.45
TestisSeminiferousTubule5.3
Thalamus6.35
Thymus4.7
Thyroid7.5
Tongue6.5
Tonsil6.1
Trachea5.1
TrigeminalGanglion7.05
Uterus4.95
UterusCorpus6.05
WholeBlood6.7
Wholebrain4.95
colon6.2
pineal_day7.48
pineal_night7.38
retina7.45
small_intestine5.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5623_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.71 ± 1.06
Basal Forebrain2.42 ± 0.17
Basal Part of Pons1.95 ± 0.33
Cerebellar Cortex2.04 ± 0.69
Cerebellar Nuclei2.75 ± 0.93
Claustrum3.23 ± 0.81
Epithalamus2.02 ± 0.82
Frontal Lobe2.13 ± 0.65
Globus Pallidus2.84 ± 0.44
Hypothalamus2.43 ± 0.71
Insula2.18 ± 0.53
Limbic Lobe2.3 ± 0.66
Mesencephalon2.52 ± 0.78
Myelencephalon2.34 ± 0.7
Occipital Lobe2.39 ± 0.56
Parietal Lobe2.3 ± 0.75
Pontine Tegmentum2.43 ± 0.72
Striatum3.22 ± 0.95
Subthalamus2.55 ± 0.81
Temporal Lobe2.19 ± 0.63
Thalamus2.31 ± 0.63
White Matter2.59 ± 0.15
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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