AutismKB 2.0

Annotation Detail for PROM1


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Basic Information Top
Gene Symbol:PROM1 ( AC133,CD133,CORD12,MCDR2,PROML1,RP41,STGD4 )
Gene Full Name: prominin 1
Band: 4p15.32
Quick LinksEntrez ID:8842; OMIM: 604365; Uniprot ID:PROM1_HUMAN; ENSEMBL ID: ENSG00000007062; HGNC ID: 9454
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst9 / 62319144
fetus24 / 56401242
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult90 / 193912146
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor8 / 11424670
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor48 / 263845181
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal109 / 336030732
ovarian tumor3 / 7668239
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain30 / 110098927
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue16 / 21572274
esophagus0 / 202090 
eye11 / 21105452
heart0 / 896260 
intestine14 / 23447259
kidney3 / 21177714
larynx1 / 2414541
liver2 / 2077439
lung9 / 33697426
lymph0 / 442700 
lymph node0 / 916100 
mammary gland11 / 15327171
mouth1 / 6705214
muscle5 / 10771546
nerve1 / 1576863
ovary3 / 10205129
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta9 / 28082532
prostate0 / 1893450 
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach4 / 9661941
testis50 / 330442151
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea96 / 524131831
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204304_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.2
Adipocyte6.45
AdrenalCortex8.4
Adrenalgland6.2
Amygdala7
Appendix8.5
AtrioventricularNode9.25
BDCA4+_DentriticCells6.55
Bonemarrow7.4
BronchialEpithelialCells6.5
CD105+_Endothelial6.8
CD14+_Monocytes7.15
CD19+_BCells(neg._sel.)6.8
CD33+_Myeloid8.4
CD34+319.85
CD4+_Tcells6.85
CD56+_NKCells7.3
CD71+_EarlyErythroid6.35
CD8+_Tcells5.75
CardiacMyocytes10.25
Caudatenucleus7.85
Cerebellum5.7
CerebellumPeduncles8.25
CiliaryGanglion5.55
CingulateCortex7
Colorectaladenocarcinoma6.75
DorsalRootGanglion5.7
FetalThyroid6.65
Fetalbrain109.9
Fetalliver6.1
Fetallung12
GlobusPallidus5.6
Heart10.55
Hypothalamus7.15
Kidney11.6
Leukemia_chronicMyelogenousK-5626.1
Leukemia_promyelocytic-HL-605.9
Leukemialymphoblastic(MOLT-4)5.2
Liver10.15
Lung7.45
Lymphnode5.55
Lymphoma_burkitts(Daudi)8.95
Lymphoma_burkitts(Raji)9.95
MedullaOblongata6.05
OccipitalLobe6.1
OlfactoryBulb5.3
Ovary4.9
Pancreas18.05
PancreaticIslet33.65
ParietalLobe7.65
Pituitary7.9
Placenta10.75
Pons6.85
PrefrontalCortex8.25
Prostate7.8
Salivarygland86.1
SkeletalMuscle9.65
Skin8.35
SmoothMuscle7.55
Spinalcord7.5
SubthalamicNucleus6.5
SuperiorCervicalGanglion12.1
TemporalLobe6.5
Testis5.95
TestisGermCell6.75
TestisIntersitial8.65
TestisLeydigCell7.7
TestisSeminiferousTubule6
Thalamus7.2
Thymus5.1
Thyroid22.75
Tongue7.55
Tonsil6.8
Trachea168.3
TrigeminalGanglion8.8
Uterus5.6
UterusCorpus6.8
WholeBlood7.05
Wholebrain5.6
colon147.8
pineal_day8.4
pineal_night8.46
retina86.85
small_intestine32.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16071_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.93 ± 1.02
Basal Forebrain2.58 ± 0.44
Basal Part of Pons2.24 ± 0.5
Cerebellar Cortex2.49 ± 0.83
Cerebellar Nuclei3.1 ± 0.74
Claustrum3.4 ± 0.81
Epithalamus3.58 ± 0.53
Frontal Lobe2.57 ± 0.72
Globus Pallidus3.14 ± 0.46
Hypothalamus2.45 ± 0.79
Insula2.36 ± 0.74
Limbic Lobe2.55 ± 0.64
Mesencephalon2.75 ± 0.66
Myelencephalon2.65 ± 0.7
Occipital Lobe2.66 ± 0.8
Parietal Lobe2.52 ± 0.68
Pontine Tegmentum2.79 ± 0.77
Striatum2.84 ± 0.59
Subthalamus3.04 ± 0.82
Temporal Lobe2.51 ± 0.74
Thalamus2.62 ± 0.66
White Matter2.77 ± 0.15
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00803420 13 321 333 LSLSQLNSNPELR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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